Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Pediatric Radiology
Erschienen in: Pediatric Radiology 3/2015

01.09.2015 | Advances in Pediatric Neuroradiology

Review of diffusion tensor imaging and its application in children

verfasst von: Gregory A. Vorona, Jeffrey I. Berman

Erschienen in: Pediatric Radiology | Sonderheft 3/2015

Einloggen, um Zugang zu erhalten

Abstract

Diffusion MRI is an imaging technique that uses the random motion of water to probe tissue microstructure. Diffusion tensor imaging (DTI) can quantitatively depict the organization and connectivity of white matter. Given the non-invasiveness of the technique, DTI has become a widely used tool for researchers and clinicians to examine the white matter of children. This review covers the basics of diffusion-weighted imaging and diffusion tensor imaging and discusses examples of their clinical application in children.
Literatur
1.
Yang E, Nucifora PG, Melhem ER (2011) Diffusion MR imaging: basic principles. Neuroimaging Clin N Am 21:1–25CrossRefPubMed
2.
Einstein A (1905) On the movement of small particles suspended in stationary liquids required by the molecular-kinetic theory of heat. Ann Phys 17:549–560
3.
Basser PJ, Mattiello J, LeBihan D (1994) Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B 103:247–254CrossRefPubMed
4.
Huisman TA (2010) Diffusion-weighted and diffusion tensor imaging of the brain, made easy. Cancer Imaging 10A:S163–S171CrossRef
5.
Moseley ME, Cohen Y, Mintorovitch J et al (1990) Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 14:330–346CrossRefPubMed
6.
Tanner JE, Stejskal EO (1968) Restricted self-diffusion of protons in colloidal systems by the pulsed-gradient, spin-echo method. J Chem Phys 49:1768–1777CrossRef
7.
Mori S, Tournier JD (2014) Introduction to diffusion tensor imaging and higher order models. Elsevier/Academic Press, Amsterdam Boston
8.
Mukherjee P, Berman JI, Chung SW et al (2008) Diffusion tensor MR imaging and fiber tractography: theoretic underpinnings. AJNR Am J Neuroradiol 29:632–641CrossRefPubMed
9.
Beaulieu C (2002) The basis of anisotropic water diffusion in the nervous system — a technical review. NMR Biomed 15:435–455CrossRefPubMed
10.
Choudhri AF, Chin EM, Blitz AM et al (2014) Diffusion tensor imaging of cerebral white matter: technique, anatomy, and pathologic patterns. Radiol Clin N Am 52:413–425CrossRefPubMed
11.
12.
Mukherjee P, Chung SW, Berman JI et al (2008) Diffusion tensor MR imaging and fiber tractography: technical considerations. AJNR Am J Neuroradiol 29:843–852
13.
Wimberger DM, Roberts TP, Barkovich AJ et al (1995) Identification of ‘premyelination’ by diffusion-weighted MRI. J Comput Assist Tomogr 19:28–33CrossRefPubMed
14.
Counsell SJ, Maalouf EF, Fletcher AM et al (2002) MR imaging assessment of myelination in the very preterm brain. AJNR Am J Neuroradiol 23:872–881PubMed
15.
Garel C, Chantrel E, Elmaleh M et al (2003) Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination. Childs Nerv Syst 19:422–425CrossRefPubMed
16.
Welker KM, Patton A (2012) Assessment of normal myelination with magnetic resonance imaging. Semin Neurol 32:15–28CrossRefPubMed
17.
Oishi K, Faria AV, Yoshida S et al (2013) Quantitative evaluation of brain development using anatomical MRI and diffusion tensor imaging. Int J Dev Neurosci 31:512–524CrossRefPubMed
18.
19.
Mukherjee P, Miller JH, Shimony JS et al (2001) Normal brain maturation during childhood: developmental trends characterized with diffusion-tensor MR imaging. Radiology 221:349–358CrossRefPubMed
20.
Partridge SC, Mukherjee P, Henry RG et al (2004) Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns. Neuroimage 22:1302–1314CrossRefPubMed
21.
Hermoye L, Saint-Martin C, Cosnard G et al (2006) Pediatric diffusion tensor imaging: normal database and observation of the white matter maturation in early childhood. Neuroimage 29:493–504CrossRefPubMed
22.
Eluvathingal TJ, Hasan KM, Kramer L et al (2007) Quantitative diffusion tensor tractography of association and projection fibers in normally developing children and adolescents. Cereb Cortex 17:2760–2768CrossRefPubMedCentralPubMed
23.
Giorgio A, Watkins KE, Douaud G et al (2008) Changes in white matter microstructure during adolescence. Neuroimage 39:52–61CrossRefPubMed
24.
Wu M, Lu LH, Lowes A et al (2014) Development of superficial white matter and its structural interplay with cortical gray matter in children and adolescents. Hum Brain Mapp 35:2806–2816CrossRefPubMed
25.
Chokshi FH, Poretti A, Meoded A et al (2011) Normal and abnormal development of the cerebellum and brainstem as depicted by diffusion tensor imaging. Semin Ultrasound CT MR 32:539–554CrossRefPubMed
26.
Lee SK, Kim DI, Kim J et al (2005) Diffusion-tensor MR imaging and fiber tractography: a new method of describing aberrant fiber connections in developmental CNS anomalies. Radiographics 25:53–65, discussion 66–68CrossRefPubMed
27.
Poretti A, Meoded A, Rossi A et al (2013) Diffusion tensor imaging and fiber tractography in brain malformations. Pediatr Radiol 43:28–54CrossRefPubMed
28.
Rollins NK (2007) Clinical applications of diffusion tensor imaging and tractography in children. Pediatr Radiol 37:769–780CrossRefPubMed
29.
30.
Barkovich AJ, Raybaud C (2012) Pediatric neuroimaging. Lippincott, Williams & Wilkins/Wolters Kluwer Health, Philadelphia
31.
Lee SK, Mori S, Kim DJ et al (2004) Diffusion tensor MR imaging visualizes the altered hemispheric fiber connection in callosal dysgenesis. AJNR Am J Neuroradiol 25:25–28PubMed
32.
Nakata Y, Barkovich AJ, Wahl M et al (2009) Diffusion abnormalities and reduced volume of the ventral cingulum bundle in agenesis of the corpus callosum: a 3T imaging study. AJNR Am J Neuroradiol 30:1142–1148CrossRefPubMedCentralPubMed
33.
Tovar-Moll F, Moll J, de Oliveira-Souza R et al (2007) Neuroplasticity in human callosal dysgenesis: a diffusion tensor imaging study. Cereb Cortex 17:531–541CrossRefPubMed
34.
Utsunomiya H, Yamashita S, Takano K et al (2006) Arrangement of fiber tracts forming Probst bundle in complete callosal agenesis: report of two cases with an evaluation by diffusion tensor tractography. Acta Radiol 47:1063–1066CrossRefPubMed
35.
Wahl M, Strominger Z, Jeremy RJ et al (2009) Variability of homotopic and heterotopic callosal connectivity in partial agenesis of the corpus callosum: a 3T diffusion tensor imaging and Q-ball tractography study. AJNR Am J Neuroradiol 30:282–289CrossRefPubMed
36.
Aziz ZA, Saini J, Bindu PS et al (2013) Demonstration of different histological layers of the pachygyria/agyria cortex using diffusion tensor MR imaging. Surg Radiol Anat 35:427–433CrossRefPubMed
37.
Rollins N, Reyes T, Chia J (2005) Diffusion tensor imaging in lissencephaly. AJNR Am J Neuroradiol 26:1583–1586PubMed
38.
Kao YC, Peng SS, Weng WC et al (2011) Evaluation of white matter changes in agyria-pachygyria complex using diffusion tensor imaging. J Child Neurol 26:433–439CrossRefPubMed
39.
Colombo N, Salamon N, Raybaud C et al (2009) Imaging of malformations of cortical development. Epileptic Disord 11:194–205PubMed
40.
41.
Madan N, Grant PE (2009) New directions in clinical imaging of cortical dysplasias. Epilepsia 50:9–18CrossRefPubMed
42.
Blumcke I, Thom M, Aronica E et al (2011) The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc task force of the ILAE Diagnostic Methods Commission. Epilepsia 52:158–174CrossRefPubMedCentralPubMed
43.
Dumas de la Roque A, Oppenheim C, Chassoux F et al (2005) Diffusion tensor imaging of partial intractable epilepsy. Eur Radiol 15:279–285CrossRefPubMed
44.
Eriksson SH, Rugg-Gunn FJ, Symms MR et al (2001) Diffusion tensor imaging in patients with epilepsy and malformations of cortical development. Brain 124:617–626CrossRefPubMed
45.
Gross DW, Bastos A, Beaulieu C (2005) Diffusion tensor imaging abnormalities in focal cortical dysplasia. Can J Neurol Sci 32:477–482CrossRefPubMed
46.
Lee SK, Kim DI, Mori S et al (2004) Diffusion tensor MRI visualizes decreased subcortical fiber connectivity in focal cortical dysplasia. Neuroimage 22:1826–1829CrossRefPubMed
47.
Widjaja E, Blaser S, Miller E et al (2007) Evaluation of subcortical white matter and deep white matter tracts in malformations of cortical development. Epilepsia 48:1460–1469CrossRefPubMed
48.
Chen Q, Lui S, Li CX et al (2008) MRI-negative refractory partial epilepsy: role for diffusion tensor imaging in high field MRI. Epilepsy Res 80:83–89CrossRefPubMed
49.
Widjaja E, Zarei Mahmoodabadi S, Otsubo H et al (2009) Subcortical alterations in tissue microstructure adjacent to focal cortical dysplasia: detection at diffusion-tensor MR imaging by using magnetoencephalographic dipole cluster localization. Radiology 251:206–215CrossRefPubMed
50.
Diehl B, Tkach J, Piao Z et al (2010) Diffusion tensor imaging in patients with focal epilepsy due to cortical dysplasia in the temporo-occipital region: electro-clinico-pathological correlations. Epilepsy Res 90:178–187CrossRefPubMed
51.
Tuch DS, Reese TG, Wiegell MR et al (2003) Diffusion MRI of complex neural architecture. Neuron 40:885–895CrossRefPubMed
52.
Wedeen VJ, Hagmann P, Tseng W-YI et al (2005) Mapping complex tissue architecture with diffusion spectrum magnetic resonance imaging. Magn Res Med 54:1377–1386CrossRef
Metadaten
Titel
Review of diffusion tensor imaging and its application in children
verfasst von
Gregory A. Vorona
Jeffrey I. Berman
Publikationsdatum
01.09.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe Sonderheft 3/2015
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-015-3277-0

Weitere Artikel der Sonderheft 3/2015

Pediatric Radiology 3/2015 Zur Ausgabe

Advances in Pediatric Neuroradiology

Pediatric applications of functional magnetic resonance imaging

Advances in Pediatric Neuroradiology

Introduction to ‘Advances in Pediatric Neuroradiology’

Advances in Pediatric Neuroradiology

Pediatric brain tumors

Advances in Pediatric Neuroradiology

Congenital spine anomalies: the closed spinal dysraphisms

Advances in Pediatric Neuroradiology

Neurometabolic diseases of childhood

Advances in Pediatric Neuroradiology

Central nervous system injury in utero: selected entities

Neu im Fachgebiet Radiologie

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise