Skip to main content
Erschienen in: International Orthopaedics 6/2012

01.06.2012 | Original Paper

Bone mineral density is not related to heterotopic ossification after total hip arthroplasty

verfasst von: Kunihiko Okano, Kiyoshi Aoyagi, Makoto Osaki, Satoru Motokawa, Tomoko Matsumoto

Erschienen in: International Orthopaedics | Ausgabe 6/2012

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Heterotopic ossification (HO) after total hip arthroplasty (THA) is a frequent complication that compromises the success of this procedure; however, its precise pathogenesis is unknown. Patient-related risk factors have previously been investigated to predict patients likely to have HO. In this study, we compared bone mineral density (BMD) between patients with and without HO after THA.

Methods

We measured BMD of the lumbar spine, radius, and calcaneus using dual-energy X-ray absorptiometry in 98 females who were scheduled to undergo THA. Radiographs were graded for the presence of HO according to the criteria of Brooker at a minimum follow-up of two years following THA. BMD were compared between those with HO and those without.

Results

In total, HO was observed in 20 of 98 hips. There were no significant differences in age, height, weight, body mass index, and pre-operative total hip score between the HO and non-HO groups. No significant difference was observed in BMD of the lumbar spine, distal radius, mid-radius, and calcaneus between the two groups.

Conclusions

Our findings suggest that generalized BMD is not related to the occurrence of HO after THA in women.
Literatur
1.
Zurück zum Zitat Ahrengart L (1991) Periarticular heterotopic ossification after total hip arthroplasty. Risk factors and consequences. Clin Orthop Relat Res 263:49–58PubMed Ahrengart L (1991) Periarticular heterotopic ossification after total hip arthroplasty. Risk factors and consequences. Clin Orthop Relat Res 263:49–58PubMed
2.
Zurück zum Zitat Ahrengart L, Lindgren U (1993) Heterotopic bone after hip arthroplasty. Defining the patient at risk. Clin Orthop Relat Res 293:153–159PubMed Ahrengart L, Lindgren U (1993) Heterotopic bone after hip arthroplasty. Defining the patient at risk. Clin Orthop Relat Res 293:153–159PubMed
3.
Zurück zum Zitat Antoniades L, MacGregor AJ, Matson M, Spector TD (2000) A cotwin control study of the relationship between hip osteoarthritis and bone mineral density. Arthritis Rheum 43:1450–1455PubMedCrossRef Antoniades L, MacGregor AJ, Matson M, Spector TD (2000) A cotwin control study of the relationship between hip osteoarthritis and bone mineral density. Arthritis Rheum 43:1450–1455PubMedCrossRef
4.
Zurück zum Zitat Board TN, Karva A, Board RE, Gambhir AK, Porter ML (2007) The prophylaxis and treatment of heterotopic ossification following lower limb arthroplasty. J Bone Joint Surg Br 89:434–440PubMedCrossRef Board TN, Karva A, Board RE, Gambhir AK, Porter ML (2007) The prophylaxis and treatment of heterotopic ossification following lower limb arthroplasty. J Bone Joint Surg Br 89:434–440PubMedCrossRef
5.
Zurück zum Zitat Bolotin HH (2007) DXA in vivo BMD methodology: an erroneous and misleading research and clinical gauge of bone mineral status, bone fragility, and bone remodelling. Bone 41:138–154PubMedCrossRef Bolotin HH (2007) DXA in vivo BMD methodology: an erroneous and misleading research and clinical gauge of bone mineral status, bone fragility, and bone remodelling. Bone 41:138–154PubMedCrossRef
6.
Zurück zum Zitat Bombelli R (1983) Osteoarthritis of the hip: classification and pathogenesis, 2nd edn. Springer, Berlin Bombelli R (1983) Osteoarthritis of the hip: classification and pathogenesis, 2nd edn. Springer, Berlin
7.
Zurück zum Zitat Brooker AF, Bowerman JW, Robinson RA, Riley LH Jr (1973) Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am 55:1629–1632PubMed Brooker AF, Bowerman JW, Robinson RA, Riley LH Jr (1973) Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am 55:1629–1632PubMed
8.
Zurück zum Zitat Bruno RJ, Sauer PA, Rosenberg AG, Block J, Sumner DR (1999) The pattern of bone mineral density in the proximal femur and radiographic signs of early joint degeneration. J Rheumatol 26:636–640PubMed Bruno RJ, Sauer PA, Rosenberg AG, Block J, Sumner DR (1999) The pattern of bone mineral density in the proximal femur and radiographic signs of early joint degeneration. J Rheumatol 26:636–640PubMed
9.
Zurück zum Zitat Burger H, van Daele PL, Odding E, Valkenburg HA, Hofman A, Grobbee DE, Schutte HE, Birkenhager JC, Pols HA (1996) Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The Rotterdam Study. Arthritis Rheum 39:81–86PubMedCrossRef Burger H, van Daele PL, Odding E, Valkenburg HA, Hofman A, Grobbee DE, Schutte HE, Birkenhager JC, Pols HA (1996) Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The Rotterdam Study. Arthritis Rheum 39:81–86PubMedCrossRef
10.
Zurück zum Zitat DeLee J, Ferrari A, Charnley J (1976) Ectopic bone formation following low friction arthroplasty of the hip. Clin Orthop Relat Res 121:53–59PubMed DeLee J, Ferrari A, Charnley J (1976) Ectopic bone formation following low friction arthroplasty of the hip. Clin Orthop Relat Res 121:53–59PubMed
11.
Zurück zum Zitat Gotfredsen A, Riis BJ, Christiansen C, Rodbro P (1990) Does a single local absorptiometric bone measurement indicate the overall skeletal status? Implications for osteoporosis and osteoarthritis of the hip. Clin Rheumatol 9:193–203PubMedCrossRef Gotfredsen A, Riis BJ, Christiansen C, Rodbro P (1990) Does a single local absorptiometric bone measurement indicate the overall skeletal status? Implications for osteoporosis and osteoarthritis of the hip. Clin Rheumatol 9:193–203PubMedCrossRef
12.
Zurück zum Zitat Hannan MT, Anderson JJ, Zhang Y, Levy D, Felson DT (1993) Bone mineral density and knee osteoarthritis in elderly men and women. The Framingham Study. Arthritis Rheum 36:1671–1680PubMedCrossRef Hannan MT, Anderson JJ, Zhang Y, Levy D, Felson DT (1993) Bone mineral density and knee osteoarthritis in elderly men and women. The Framingham Study. Arthritis Rheum 36:1671–1680PubMedCrossRef
13.
Zurück zum Zitat Higo T, Mawatari M, Shigematsu M, Hotokebuchi T (2006) The incidence of heterotopic ossification after cementless total hip arthroplasty. J Arthroplasty 21:852–856PubMedCrossRef Higo T, Mawatari M, Shigematsu M, Hotokebuchi T (2006) The incidence of heterotopic ossification after cementless total hip arthroplasty. J Arthroplasty 21:852–856PubMedCrossRef
14.
Zurück zum Zitat Jordan GR, Loveridge N, Bell KL, Power J, Dickson GR, Vedi S, Rushton N, Clarke MT, Reeve J (2003) Increased femoral neck cancellous bone and connectivity in coxarthrosis (hip osteoarthritis). Bone 32:86–95PubMedCrossRef Jordan GR, Loveridge N, Bell KL, Power J, Dickson GR, Vedi S, Rushton N, Clarke MT, Reeve J (2003) Increased femoral neck cancellous bone and connectivity in coxarthrosis (hip osteoarthritis). Bone 32:86–95PubMedCrossRef
15.
Zurück zum Zitat Lim LS, Hoeksema LJ, Sherin K (2009) Screening for osteoporosis in the adult U.S. population: ACPM position statement on preventive practice. Am J Prev Med 36:366–375PubMedCrossRef Lim LS, Hoeksema LJ, Sherin K (2009) Screening for osteoporosis in the adult U.S. population: ACPM position statement on preventive practice. Am J Prev Med 36:366–375PubMedCrossRef
16.
Zurück zum Zitat Makinen TJ, Alm JJ, Laine H, Svedstrom E, Aro HT (2007) The incidence of osteopenia and osteoporosis in women with hip osteoarthritis scheduled for cementless total joint replacement. Bone 40:1041–1047PubMedCrossRef Makinen TJ, Alm JJ, Laine H, Svedstrom E, Aro HT (2007) The incidence of osteopenia and osteoporosis in women with hip osteoarthritis scheduled for cementless total joint replacement. Bone 40:1041–1047PubMedCrossRef
17.
Zurück zum Zitat Merle D’Aubigne R, Postel M (1954) Function al results of hip arthroplasty with acrylic prosthesis. J Bone Joint Surg Am 36-A:451–475 Merle D’Aubigne R, Postel M (1954) Function al results of hip arthroplasty with acrylic prosthesis. J Bone Joint Surg Am 36-A:451–475
18.
Zurück zum Zitat Nevitt MC, Lane NE, Scott JC, Hochberg MC, Pressman AR, Genant HK, Cummings SR (1995) Radiographic osteoarthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group. Arthritis Rheum 38:907–916PubMedCrossRef Nevitt MC, Lane NE, Scott JC, Hochberg MC, Pressman AR, Genant HK, Cummings SR (1995) Radiographic osteoarthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group. Arthritis Rheum 38:907–916PubMedCrossRef
19.
Zurück zum Zitat Pai VS (1994) Heterotopic ossification in total hip arthroplasty. The influence of the approach. J Arthroplasty 9:199–202PubMedCrossRef Pai VS (1994) Heterotopic ossification in total hip arthroplasty. The influence of the approach. J Arthroplasty 9:199–202PubMedCrossRef
20.
Zurück zum Zitat Ritter MA, Vaughan RB (1977) Ectopic ossification after total hip arthroplasty. Predisposing factors, frequency, and effect on results. J Bone Joint Surg Am 59:345–351PubMed Ritter MA, Vaughan RB (1977) Ectopic ossification after total hip arthroplasty. Predisposing factors, frequency, and effect on results. J Bone Joint Surg Am 59:345–351PubMed
21.
Zurück zum Zitat Sambrook P, Naganathan V (1997) What is the relationship between osteoarthritis and osteoporosis? Baillieres Clin Rheumatol 11:695–710PubMedCrossRef Sambrook P, Naganathan V (1997) What is the relationship between osteoarthritis and osteoporosis? Baillieres Clin Rheumatol 11:695–710PubMedCrossRef
22.
Zurück zum Zitat Schnitzler CM, Mesquita JM, Wane L (1992) Bone histomorphometry of the iliac crest, and spinal fracture prevalence in atrophic and hypertrophic osteoarthritis of the hip. Osteoporos Int 2:186–194PubMedCrossRef Schnitzler CM, Mesquita JM, Wane L (1992) Bone histomorphometry of the iliac crest, and spinal fracture prevalence in atrophic and hypertrophic osteoarthritis of the hip. Osteoporos Int 2:186–194PubMedCrossRef
23.
Zurück zum Zitat Sneath RJ, Bindi FD, Davies J, Parnell EJ (2001) The effect of pulsed irrigation on the incidence of heterotopic ossification after total hip arthroplasty. J Arthroplasty 16:547–551PubMedCrossRef Sneath RJ, Bindi FD, Davies J, Parnell EJ (2001) The effect of pulsed irrigation on the incidence of heterotopic ossification after total hip arthroplasty. J Arthroplasty 16:547–551PubMedCrossRef
24.
Zurück zum Zitat Sundaram NA, Murphy JC (1986) Heterotopic bone formation following total hip arthroplasty in ankylosing spondylitis. Clin Orthop Relat Res 207:223–226PubMed Sundaram NA, Murphy JC (1986) Heterotopic bone formation following total hip arthroplasty in ankylosing spondylitis. Clin Orthop Relat Res 207:223–226PubMed
25.
Zurück zum Zitat Xue D, Zheng Q, Li H, Qian S, Zhang B, Pan Z (2011) Selective COX-2 inhibitor versus nonselective COX-1 and COX-2 inhibitor in the prevention of heterotopic ossification after total hip arthroplasty: a meta-analysis of randomised trials. Int Orthop 35:3–8PubMedCrossRef Xue D, Zheng Q, Li H, Qian S, Zhang B, Pan Z (2011) Selective COX-2 inhibitor versus nonselective COX-1 and COX-2 inhibitor in the prevention of heterotopic ossification after total hip arthroplasty: a meta-analysis of randomised trials. Int Orthop 35:3–8PubMedCrossRef
Metadaten
Titel
Bone mineral density is not related to heterotopic ossification after total hip arthroplasty
verfasst von
Kunihiko Okano
Kiyoshi Aoyagi
Makoto Osaki
Satoru Motokawa
Tomoko Matsumoto
Publikationsdatum
01.06.2012
Verlag
Springer-Verlag
Erschienen in
International Orthopaedics / Ausgabe 6/2012
Print ISSN: 0341-2695
Elektronische ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-011-1446-9

Weitere Artikel der Ausgabe 6/2012

International Orthopaedics 6/2012 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

TEP mit Roboterhilfe führt nicht zu größerer Zufriedenheit

15.05.2024 Knie-TEP Nachrichten

Der Einsatz von Operationsrobotern für den Einbau von Totalendoprothesen des Kniegelenks hat die Präzision der Eingriffe erhöht. Für die postoperative Zufriedenheit der Patienten scheint das aber unerheblich zu sein, wie eine Studie zeigt.

Lever-Sign-Test hilft beim Verdacht auf Kreuzbandriss

15.05.2024 Vordere Kreuzbandruptur Nachrichten

Mit dem Hebelzeichen-Test lässt sich offenbar recht zuverlässig feststellen, ob ein vorderes Kreuzband gerissen ist. In einer Metaanalyse war die Vorhersagekraft vor allem bei positivem Testergebnis hoch.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Klinik aktuell Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

03.05.2024 Fibromyalgiesyndrom Nachrichten

Bewegungs-, Dehnungs- und Entspannungsübungen im Wasser lindern die Beschwerden von Patientinnen mit Fibromyalgie besser als das Üben auf trockenem Land. Das geht aus einer spanisch-brasilianischen Vergleichsstudie hervor.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.