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Erschienen in: Aesthetic Plastic Surgery 4/2010

01.08.2010 | Original Article

Scar Prevention Using Laser-Assisted Skin Healing (LASH) in Plastic Surgery

verfasst von: Alexandre Capon, Gwen Iarmarcovai, David Gonnelli, Nathalie Degardin, Guy Magalon, Serge Mordon

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 4/2010

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Abstract

Background

The use of lasers has been proposed for scar revision. A recent pilot clinical study demonstrated that lasers could also be used immediately after surgery to reduce the appearance of scars. The LASH (Laser-Assisted Skin Healing) technique induces a temperature elevation in the skin which modifies the wound-healing process. We report a prospective comparative clinical trial aimed at evaluating an 810-nm diode-laser system to accelerate and improve the healing process in surgical scars immediately after skin closure.

Methods

Twenty-nine women and 1 man (mean age = 41.4 years; Fitzpatrick skin types I-IV) were included to evaluate the safety and performance of the laser system. The laser dose (or fluence in J/cm²) was selected as a function of phototype and skin thickness. Each surgical incision (e.g., abdominoplasty) was divided into two parts. An 8-cm segment was treated with the laser immediately after skin closure. A separate 8-cm segment was left untreated as a control. Clinical evaluations (overall appearance ratings, comparative scar scale) of all scars were conducted at 10 days, 3 months, and 12 months by both surgeon and patients. Profilometry analysis from silicone replicas of the skin was done at 12 months. Wilcoxon signed-rank test analyses were performed.

Results

Twenty-two patients were treated using a high dose (80–130 J/cm²) and 8 patients with a low dose (<80 J/cm²). At 12 months in the high-dose group, both surgeon and patients reported an improvement rate of the laser-treated segment over the control area of 72.73 and 59.10%, respectively. For these patients, profilometry results showed a decrease in scar height of 38.1% (p = 0.027) at 12 months for the laser-treated segment versus control. Three patients treated with higher doses (>115 J/cm²) experienced superficial burns on the laser-treated segment, which resolved in about 5–7 days. For the eight patients treated at low dosage (<80 J/cm²), there was no significant difference in the treated segment versus the control segment. No side effects were observed.

Conclusion

This prospective comparative trial demonstrates that an 810-nm diode laser treatment, performed immediately after surgery, can improve the appearance of a surgical scar. The dose plays a great role in scar improvement and must be well controlled. There is interest in LASH for hypertrophic scar revision. LASH can be used to prevent and reduce scars in plastic surgery.
Literatur
1.
Zurück zum Zitat Rhett JM, Ghatnekar GS, Palatinus JA, O’Quinn M, Yost MJ, Gourdie RG (2008) Novel therapies for scar reduction and regenerative healing of skin wounds. Trends Biotechnol 26:173–180CrossRefPubMed Rhett JM, Ghatnekar GS, Palatinus JA, O’Quinn M, Yost MJ, Gourdie RG (2008) Novel therapies for scar reduction and regenerative healing of skin wounds. Trends Biotechnol 26:173–180CrossRefPubMed
2.
Zurück zum Zitat Mustoe TA, Cooter RD, Gold MH, Hobbs FD, Ramelet AA et al (2002) International clinical recommendations on scar management. Plast Reconstr Surg 110:560–571CrossRefPubMed Mustoe TA, Cooter RD, Gold MH, Hobbs FD, Ramelet AA et al (2002) International clinical recommendations on scar management. Plast Reconstr Surg 110:560–571CrossRefPubMed
3.
Zurück zum Zitat Tierney E, Mahmoud BH, Srivastava D, Ozog D, Kouba DJ (2009) Treatment of surgical scars with nonablative fractional laser versus pulsed dye laser: a randomized controlled trial. Dermatol Surg 35(8):1172–1180CrossRefPubMed Tierney E, Mahmoud BH, Srivastava D, Ozog D, Kouba DJ (2009) Treatment of surgical scars with nonablative fractional laser versus pulsed dye laser: a randomized controlled trial. Dermatol Surg 35(8):1172–1180CrossRefPubMed
4.
Zurück zum Zitat Colwell AS, Longaker MT, Lorenz HP (2003) Fetal wound healing. Front Biosci 8:1240–1248CrossRef Colwell AS, Longaker MT, Lorenz HP (2003) Fetal wound healing. Front Biosci 8:1240–1248CrossRef
5.
Zurück zum Zitat West TB (1997) Laser resurfacing of atrophic scars. Dermatol Clin 15:449–457PubMed West TB (1997) Laser resurfacing of atrophic scars. Dermatol Clin 15:449–457PubMed
7.
Zurück zum Zitat Chan HH, Wong DS, Ho WS, Lam LK, Wei W (2004) The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons. Dermatol Surg 30:987–994 discussion 994CrossRefPubMed Chan HH, Wong DS, Ho WS, Lam LK, Wei W (2004) The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons. Dermatol Surg 30:987–994 discussion 994CrossRefPubMed
8.
Zurück zum Zitat Kye YC (2003) Laser therapy of skin diseases. Korean J Dermatol 2003:1–6 Kye YC (2003) Laser therapy of skin diseases. Korean J Dermatol 2003:1–6
9.
Zurück zum Zitat Nouri K, Jimenez GP, Harrison-Balestra C, Elgart GW (2003) 585-nm pulsed dye laser in the treatment of surgical scars starting on the suture removal day. Dermatol Surg 29:65–73CrossRefPubMed Nouri K, Jimenez GP, Harrison-Balestra C, Elgart GW (2003) 585-nm pulsed dye laser in the treatment of surgical scars starting on the suture removal day. Dermatol Surg 29:65–73CrossRefPubMed
10.
Zurück zum Zitat Conologue TD, Norwood C (2006) Treatment of surgical scars with the cryogen-cooled 595 nm pulsed dye laser starting on the day of suture removal. Dermatol Surg 32:13–20PubMed Conologue TD, Norwood C (2006) Treatment of surgical scars with the cryogen-cooled 595 nm pulsed dye laser starting on the day of suture removal. Dermatol Surg 32:13–20PubMed
11.
Zurück zum Zitat Choe JH, Park YL, Kim BJ, Kim MN, Rho NK et al (2009) Prevention of thyroidectomy scar using a new 1, 550-nm fractional erbium-glass laser. Dermatol Surg 35(8):1199–1205CrossRefPubMed Choe JH, Park YL, Kim BJ, Kim MN, Rho NK et al (2009) Prevention of thyroidectomy scar using a new 1, 550-nm fractional erbium-glass laser. Dermatol Surg 35(8):1199–1205CrossRefPubMed
12.
Zurück zum Zitat Capon A, Souil E, Gauthier B, Sumian C, Bachelet M et al (2001) Laser assisted skin closure (LASC) by using a 815-nm diode-laser system accelerates and improves wound healing. Lasers Surg Med 28:168–175CrossRefPubMed Capon A, Souil E, Gauthier B, Sumian C, Bachelet M et al (2001) Laser assisted skin closure (LASC) by using a 815-nm diode-laser system accelerates and improves wound healing. Lasers Surg Med 28:168–175CrossRefPubMed
13.
Zurück zum Zitat Capon AC, Gosse AR, Iarmarcovai GN, Cornil AH, Mordon SR (2008) Scar prevention by laser-assisted scar healing (LASH): a pilot study using an 810-nm diode-laser system. Lasers Surg Med 40:443–445CrossRefPubMed Capon AC, Gosse AR, Iarmarcovai GN, Cornil AH, Mordon SR (2008) Scar prevention by laser-assisted scar healing (LASH): a pilot study using an 810-nm diode-laser system. Lasers Surg Med 40:443–445CrossRefPubMed
14.
Zurück zum Zitat Capon A, Iarmarcovai G, Mordon S (2009) Laser-assisted skin healing (LASH) in hypertrophic scar revision. J Cosmet Laser Ther 11(4):220–223CrossRefPubMed Capon A, Iarmarcovai G, Mordon S (2009) Laser-assisted skin healing (LASH) in hypertrophic scar revision. J Cosmet Laser Ther 11(4):220–223CrossRefPubMed
15.
Zurück zum Zitat Souil E, Capon A, Mordon S, Dinh-Xuan AT, Polla BS, Bachelet M (2001) Treatment with 815-nm diode laser induces long-lasting expression of 72-kDa heat shock protein in normal rat skin. Br J Dermatol 144:260–266CrossRefPubMed Souil E, Capon A, Mordon S, Dinh-Xuan AT, Polla BS, Bachelet M (2001) Treatment with 815-nm diode laser induces long-lasting expression of 72-kDa heat shock protein in normal rat skin. Br J Dermatol 144:260–266CrossRefPubMed
16.
Zurück zum Zitat Capon A, Mordon S (2003) Can thermal lasers promote skin wound healing? Am J Clin Dermatol 4:1–12CrossRefPubMed Capon A, Mordon S (2003) Can thermal lasers promote skin wound healing? Am J Clin Dermatol 4:1–12CrossRefPubMed
17.
Zurück zum Zitat Shah M, Revis D, Herrick S, Baillie R, Thorgeirson S et al (1999) Role of elevated plasma transforming growth factor-beta1 levels in wound healing. Am J Pathol 154:1115–1124PubMed Shah M, Revis D, Herrick S, Baillie R, Thorgeirson S et al (1999) Role of elevated plasma transforming growth factor-beta1 levels in wound healing. Am J Pathol 154:1115–1124PubMed
18.
Zurück zum Zitat Dallon J, Sherratt J, Maini P, Ferguson M (2000) Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair. IMA J Math Appl Med Biol 17:379–393CrossRefPubMed Dallon J, Sherratt J, Maini P, Ferguson M (2000) Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair. IMA J Math Appl Med Biol 17:379–393CrossRefPubMed
19.
Zurück zum Zitat Dallon JC, Sherratt JA, Maini PK (2001) Modeling the effects of transforming growth factor-beta on extracellular matrix alignment in dermal wound repair. Wound Repair Regen 9:278–286CrossRefPubMed Dallon JC, Sherratt JA, Maini PK (2001) Modeling the effects of transforming growth factor-beta on extracellular matrix alignment in dermal wound repair. Wound Repair Regen 9:278–286CrossRefPubMed
20.
Zurück zum Zitat Alam M, Pon K, Van Laborde S, Kaminer MS, Arndt KA, Dover JS (2009) Clinical effect of a single pulsed dye laser treatment of fresh surgical scars: randomized controlled trial. Dermatol Surg 32(1):21–25CrossRef Alam M, Pon K, Van Laborde S, Kaminer MS, Arndt KA, Dover JS (2009) Clinical effect of a single pulsed dye laser treatment of fresh surgical scars: randomized controlled trial. Dermatol Surg 32(1):21–25CrossRef
Metadaten
Titel
Scar Prevention Using Laser-Assisted Skin Healing (LASH) in Plastic Surgery
verfasst von
Alexandre Capon
Gwen Iarmarcovai
David Gonnelli
Nathalie Degardin
Guy Magalon
Serge Mordon
Publikationsdatum
01.08.2010
Verlag
Springer-Verlag
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 4/2010
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-009-9469-y

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