Erschienen in:
12.05.2017 | Neuro
Comparison of 3D magnetic resonance imaging and digital subtraction angiography for intracranial artery stenosis
verfasst von:
Ji Eun Park, Seung Chai Jung, Sang Hun Lee, Ji Young Jeon, Ji Ye Lee, Ho Sung Kim, Choong-Gon Choi, Sang Joon Kim, Deok Hee Lee, Seon-Ok Kim, Sun U. Kwon, Dong-Wha Kang, Jong S. Kim
Erschienen in:
European Radiology
|
Ausgabe 11/2017
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Abstract
Objectives
To compare three-dimensional high-resolution magnetic resonance imaging (3D HR-MRI) and digital subtraction angiography (DSA) for diagnosing and evaluating stenosis in the entire circle of Willis.
Methods
The study included 516 intracranial arteries from 43 patients with intracranial artery stenosis (ICAS) who underwent both 3D HR-MRI and DSA within 1 month. Two readers independently diagnosed atherosclerosis, dissection, moyamoya disease and vasculitis, rated their diagnostic confidence for each vessel and measured the luminal diameters. Reference standard was made from clinico-radiologic diagnosis. Diagnostic accuracy, diagnostic confidence, the degree of stenosis and luminal diameter were assessed and compared between both modalities.
Results
For atherosclerosis, 3D HR-MRI showed better diagnostic accuracy (P = .03–.003), sensitivity (P = .006–.01) and positive predictive value (P ≤ .001–.006) compared to DSA. Overall, the readers were more confident of their diagnosis of ICAS when using 3D HR-MRI (reader 1, P ≤ .001–.007; reader 2, P ≤ .001–.015). 3D HR-MRI showed similar degree of stenosis (P > .05) and higher luminal diameter (P < .05) compared to DSA.
Conclusions
3D HR-MRI might be useful to evaluate atherosclerosis, with better diagnostic confidence and comparable stenosis measurement compared to DSA in the entire circle of Willis.
Key Points
• 3D HR-MRI showed better diagnostic accuracy for atherosclerosiscompared to DSA
• 3D HR-MRI showed better overall diagnostic confidence for stenosiscompared to DSA
• 3D HR-MRI and DSA showed similar degree of stenosis