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Erschienen in: World Journal of Urology 1/2017

19.05.2016 | Original Article

Robotic and open partial nephrectomy for complex renal tumors: a matched-pair comparison with a long-term follow-up

verfasst von: Yubin Wang, Jinkai Shao, Xin Ma, Qingshan Du, Huijie Gong, Xu Zhang

Erschienen in: World Journal of Urology | Ausgabe 1/2017

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Abstract

Objectives

To compare the surgical, functional and oncological outcomes of patients undergoing robotic partial nephrectomy (RPN) or open partial nephrectomy (OPN) for moderately or highly complex tumors (RENAL nephrometry score ≥7).

Methods

A retrospective, matched-pair analysis was performed for 380 patients who underwent either RPN (n = 190) or OPN (n = 190) for a complex renal mass in different institutions. Surgical data, pathological variables, complications and functional and oncological outcomes were reviewed.

Results

RPN is associated with less estimated blood loss (EBL) (196.8 vs 240.8 ml; p < 0.001), shorter length of hospital stay (7.8 vs 9.2 days; p < 0.001) and lower rate of postoperative complications (15.8 vs 28.9 %; p = 0.002). Patients undergoing RPN required more direct cost. In multivariable models, surgical approach was the significant predictor for the occurrence of postoperative minor complications and postoperative wound pain. Median follow-up for RPN and OPN was 49 months and 52 months, respectively. The decline of estimated glomerular filtration at the last available follow-up (RPN: 8.7 %; OPN: 10 %) was similar (p = 0.125). The 5-year recurrence-free survival rate was 95.1 % for RPN and 92.7 % for OPN (p = 0.48).

Conclusions

RPN provides acceptable and comparable results in terms of perioperative, functional and oncological outcomes compared to OPN for complex renal tumors with RENAL score ≥7. Moreover, RPN is a less invasive approach with the benefit of shorter length of hospital stay, less EBL and lower rate of postoperative complications.
Literatur
1.
Zurück zum Zitat Schiffmann J, Bianchi M, Sun M et al (2014) Trends in surgical management of T1 renal cell carcinoma. Curr Urol Rep 15:383–386CrossRefPubMed Schiffmann J, Bianchi M, Sun M et al (2014) Trends in surgical management of T1 renal cell carcinoma. Curr Urol Rep 15:383–386CrossRefPubMed
2.
Zurück zum Zitat Ljungberg B, Bensalah K, Canfield S et al (2015) EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol 67:913–924CrossRefPubMed Ljungberg B, Bensalah K, Canfield S et al (2015) EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol 67:913–924CrossRefPubMed
3.
Zurück zum Zitat MacLennan S, Imamura M, Lapitan MC et al (2012) Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer. Eur Urol 62:1097–1117CrossRefPubMed MacLennan S, Imamura M, Lapitan MC et al (2012) Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer. Eur Urol 62:1097–1117CrossRefPubMed
4.
Zurück zum Zitat White MA, Haber GP, Autorino R et al (2011) Outcomes of robotic partial nephrectomy for renal masses with nephrometry score of ≥7. Urology 77:809–813CrossRefPubMed White MA, Haber GP, Autorino R et al (2011) Outcomes of robotic partial nephrectomy for renal masses with nephrometry score of ≥7. Urology 77:809–813CrossRefPubMed
5.
Zurück zum Zitat Komninos C, Shin TY, Tuliao P et al (2014) Robotic partial nephrectomy for completely endophytic renal tumors: complications and functional and oncologic outcomes during a 4-year median period of follow-up. Urology 84:1367–1373CrossRefPubMed Komninos C, Shin TY, Tuliao P et al (2014) Robotic partial nephrectomy for completely endophytic renal tumors: complications and functional and oncologic outcomes during a 4-year median period of follow-up. Urology 84:1367–1373CrossRefPubMed
6.
Zurück zum Zitat Volpe A, Garrou D, Amparore D et al (2014) Perioperative and renal functional outcomes of elective robot-assisted partial nephrectomy (RPN) for renal tumours with high surgical complexity. BJU Int 114:903–909CrossRefPubMed Volpe A, Garrou D, Amparore D et al (2014) Perioperative and renal functional outcomes of elective robot-assisted partial nephrectomy (RPN) for renal tumours with high surgical complexity. BJU Int 114:903–909CrossRefPubMed
7.
Zurück zum Zitat Borghesi M, Schiavina R, Gan M et al (2013) Expanding utilization of robotic partial nephrectomy for clinical T1b and complex T1a renal masses. World J Urol 31:499–504CrossRefPubMed Borghesi M, Schiavina R, Gan M et al (2013) Expanding utilization of robotic partial nephrectomy for clinical T1b and complex T1a renal masses. World J Urol 31:499–504CrossRefPubMed
8.
Zurück zum Zitat Masson-Lecomte A, Bensalah K, Seringe E et al (2013) A prospective comparison of surgical and pathological outcomes obtained after robot-assisted or pure laparoscopic partial nephrectomy in moderate to complex renal tumours: results from a French multicentre collaborative study. BJU Int 111:256–263CrossRefPubMed Masson-Lecomte A, Bensalah K, Seringe E et al (2013) A prospective comparison of surgical and pathological outcomes obtained after robot-assisted or pure laparoscopic partial nephrectomy in moderate to complex renal tumours: results from a French multicentre collaborative study. BJU Int 111:256–263CrossRefPubMed
9.
Zurück zum Zitat Long JA, Yakoubi R, Lee B et al (2012) Robotic versus laparoscopic partial nephrectomy for complex tumors: comparison of perioperative outcomes. Eur Urol 61:1257–1262CrossRefPubMed Long JA, Yakoubi R, Lee B et al (2012) Robotic versus laparoscopic partial nephrectomy for complex tumors: comparison of perioperative outcomes. Eur Urol 61:1257–1262CrossRefPubMed
10.
Zurück zum Zitat Jang HJ, Song W, Suh YS et al (2014) Comparison of perioperative outcomes of robotic versus laparoscopic partial nephrectomy for complex renal tumors (RENAL nephrometry score of 7 or higher). Korean J Urol 55:808–813CrossRefPubMedPubMedCentral Jang HJ, Song W, Suh YS et al (2014) Comparison of perioperative outcomes of robotic versus laparoscopic partial nephrectomy for complex renal tumors (RENAL nephrometry score of 7 or higher). Korean J Urol 55:808–813CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Ficarra V, Minervini A, Antonelli A et al (2014) A multicentre matched-pair analysis comparing robot-assisted versus open partial nephrectomy. BJU Int 113:936–941CrossRefPubMed Ficarra V, Minervini A, Antonelli A et al (2014) A multicentre matched-pair analysis comparing robot-assisted versus open partial nephrectomy. BJU Int 113:936–941CrossRefPubMed
13.
Zurück zum Zitat Masson-Lecomte A, Yates DR, Hupertan V et al (2013) A prospective comparison of the pathologic and surgical outcomes obtained after elective treatment of renal cell carcinoma by open or robot-assisted partial nephrectomy. Urol Oncol 31:924–929CrossRefPubMed Masson-Lecomte A, Yates DR, Hupertan V et al (2013) A prospective comparison of the pathologic and surgical outcomes obtained after elective treatment of renal cell carcinoma by open or robot-assisted partial nephrectomy. Urol Oncol 31:924–929CrossRefPubMed
14.
Zurück zum Zitat Minervini A, Vittori G, Antonelli A et al (2014) Open versus robotic-assisted partial nephrectomy: a multicenter comparison study of perioperative results and complications. World J Urol 32:287–293CrossRefPubMed Minervini A, Vittori G, Antonelli A et al (2014) Open versus robotic-assisted partial nephrectomy: a multicenter comparison study of perioperative results and complications. World J Urol 32:287–293CrossRefPubMed
15.
Zurück zum Zitat Simhan J, Smaldone MC, Tsai KJ et al (2012) Perioperative outcomes of robotic and open partial nephrectomy for moderately and highly complex renal lesions. J Urol 187:2000–2004CrossRefPubMed Simhan J, Smaldone MC, Tsai KJ et al (2012) Perioperative outcomes of robotic and open partial nephrectomy for moderately and highly complex renal lesions. J Urol 187:2000–2004CrossRefPubMed
16.
Zurück zum Zitat Sprenkle PC, Power N, Ghoneim T et al (2012) Comparison of open and minimally invasive partial nephrectomy for renal tumors 4–7 centimeters. Eur Urol 61:593–599CrossRefPubMed Sprenkle PC, Power N, Ghoneim T et al (2012) Comparison of open and minimally invasive partial nephrectomy for renal tumors 4–7 centimeters. Eur Urol 61:593–599CrossRefPubMed
17.
Zurück zum Zitat Patton MW, Salevitz DA, Tyson MD 2nd et al (2016) Robot-assisted partial nephrectomy for complex renal masses. J Robot Surg. 10:27–31CrossRefPubMed Patton MW, Salevitz DA, Tyson MD 2nd et al (2016) Robot-assisted partial nephrectomy for complex renal masses. J Robot Surg. 10:27–31CrossRefPubMed
18.
Zurück zum Zitat Kutikov A, Uzzo RG (2009) The RENAL nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol 182:844–853CrossRefPubMed Kutikov A, Uzzo RG (2009) The RENAL nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol 182:844–853CrossRefPubMed
19.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Levey AS, Bosch JP, Lewis JB et al (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 16(130):461–470CrossRef Levey AS, Bosch JP, Lewis JB et al (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 16(130):461–470CrossRef
21.
Zurück zum Zitat National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39:S1–S266 National Kidney Foundation (2002) K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39:S1–S266
22.
Zurück zum Zitat Ebele JN, Sauter G, Epstein JI et al (2004) Pathology and genetics of tumours of the urinary system and male genital organs. IARC, Lyon, pp 12–43 Ebele JN, Sauter G, Epstein JI et al (2004) Pathology and genetics of tumours of the urinary system and male genital organs. IARC, Lyon, pp 12–43
23.
Zurück zum Zitat Edge SB, Byrd DR, Compton CC et al (2009) AJCC cancer staging manual, 7th edn. Springer, New York, pp 547–560 Edge SB, Byrd DR, Compton CC et al (2009) AJCC cancer staging manual, 7th edn. Springer, New York, pp 547–560
24.
Zurück zum Zitat Choi JE, You JH, Kim DK et al (2015) Comparison of perioperative outcomes between robotic and laparoscopic partial nephrectomy: a systematic review and meta-analysis. Eur Urol 67:891–901CrossRefPubMed Choi JE, You JH, Kim DK et al (2015) Comparison of perioperative outcomes between robotic and laparoscopic partial nephrectomy: a systematic review and meta-analysis. Eur Urol 67:891–901CrossRefPubMed
25.
Zurück zum Zitat Froghi S, Ahmed K, Khan MS, Dasgupta P, Challacombe B (2013) Evaluation of robotic and laparoscopic partial nephrectomy for small renal tumours (T1a). BJU Int 112:E322–E333CrossRefPubMed Froghi S, Ahmed K, Khan MS, Dasgupta P, Challacombe B (2013) Evaluation of robotic and laparoscopic partial nephrectomy for small renal tumours (T1a). BJU Int 112:E322–E333CrossRefPubMed
26.
Zurück zum Zitat Simmons MN, Fergany AF, Campbell SC (2011) Effect of parenchymal volume preservation on kidney function after partial nephrectomy. J Urol 186:405–410CrossRefPubMed Simmons MN, Fergany AF, Campbell SC (2011) Effect of parenchymal volume preservation on kidney function after partial nephrectomy. J Urol 186:405–410CrossRefPubMed
Metadaten
Titel
Robotic and open partial nephrectomy for complex renal tumors: a matched-pair comparison with a long-term follow-up
verfasst von
Yubin Wang
Jinkai Shao
Xin Ma
Qingshan Du
Huijie Gong
Xu Zhang
Publikationsdatum
19.05.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
World Journal of Urology / Ausgabe 1/2017
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-016-1849-8

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