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Erschienen in: Pediatric Surgery International 5/2015

01.05.2015 | Review Article

Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

verfasst von: John M. Hutson, Lauren Dughetti, Lefteris Stathopoulos, Bridget R. Southwell

Erschienen in: Pediatric Surgery International | Ausgabe 5/2015

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Abstract

Slow-transit constipation (STC) is a newly described subtype of intractable constipation in children which we originally identified with deficiency of substance P in axons supplying the proximal colonic muscle. When nuclear transit studies became available, the patients were found to have slow proximal colonic transit, and responded to antegrade enemas. Using the appendicostomy, we found that there was reduced frequency in propagating sequences throughout the colon. We began testing whether transcutaneous electrical stimulation (TES) could improve motility and symptoms, and over several trials have now shown that TES is remarkably effective in treating children with STC, with long-lasting effects. TES holds promise for treating STC, as well as a range of gastrointestinal motility disorders.
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Metadaten
Titel
Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)
verfasst von
John M. Hutson
Lauren Dughetti
Lefteris Stathopoulos
Bridget R. Southwell
Publikationsdatum
01.05.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Surgery International / Ausgabe 5/2015
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-015-3681-4

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