Skip to main content
Erschienen in: Surgical Endoscopy 1/2012

01.01.2012

Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies

verfasst von: Kfir Ben-David, George A. Sarosi, Juan C. Cendan, Drew Howard, Georgios Rossidis, Steven N. Hochwald

Erschienen in: Surgical Endoscopy | Ausgabe 1/2012

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Esophagectomy is a complex invasive procedure that requires exploration of multiple body cavities for removal and subsequent restoration of gastrointestinal continuity. In many institutions, esophagectomy morbidity and mortality rates remain high despite improvement of intensive care treatment. We reviewed our minimally invasive esophagectomy (MIE) experience of a consecutive series of 100 patients to analyze trends in morbidity and mortality as we transitioned from open to MIE.

Methods

A total of 105 consecutive patients who underwent operative exploration for esophagectomy from August 2007 to January 2011 were reviewed. The preoperative evaluation, operative technique, and postoperative care of these cases were evaluated and analyzed for 100 patients who have had a MIE and compared with 32 open esophagectomies 2 years prior.

Results

During the time frame of the study, 105 patients underwent an exploration for attempted esophagectomy. Resection was completed in 100 patients and was done for malignant disease in 95 patients and benign disease in 5 patients. There was one in hospital mortality due to a pulmonary embolism. There was no significant difference in postoperative complications consisting of transient left recurrent nerve injury (7 vs. 12.5%) or pneumonia (9 vs. 15.6%) in those who underwent MIE compared with open resection. However, wound infections were significantly less in patients who underwent MIE compared with open esophagectomy (1 vs. 12.5%, respectively, p = 0.01). Anastomotic leak (4 vs. 12.5%, p = 0.05) also was lower in those who underwent MIE. Median length of stay (LOS) was significantly less in patients who underwent MIE compared with open esophagectomy (7.5 vs. 14 days, p < 0.05). Finally, there was a trend toward improvement in median LOS in the 30 patients who underwent MIE during the most recent time period compared with the initial 17 patients who underwent MIE (7.5 vs. 10 days, p = 0.05)

Conclusions

Our results support the continued safe use of esophagectomy for selected esophageal diseases, including malignancy. Morbidity, especially wound infection, anastomotic leak, and length of stay is decreasing with the incorporation of minimally invasive techniques.
Literatur
1.
Zurück zum Zitat Atkins BZ, Shah AS, Hutcheson KA, Mangum JH, Pappas TN, Harpole DH Jr, D’Amico TA (2004) Reducing hospital morbidity and mortality following esophagectomy. Ann Thorac Surg 78:1170–1176 (discussion 1170–1176)PubMedCrossRef Atkins BZ, Shah AS, Hutcheson KA, Mangum JH, Pappas TN, Harpole DH Jr, D’Amico TA (2004) Reducing hospital morbidity and mortality following esophagectomy. Ann Thorac Surg 78:1170–1176 (discussion 1170–1176)PubMedCrossRef
2.
Zurück zum Zitat Collard JM, Lengele B, Otte JB, Kestens PJ (1993) En bloc and standard esophagectomies by thoracoscopy. Ann Thorac Surg 56:675–679PubMedCrossRef Collard JM, Lengele B, Otte JB, Kestens PJ (1993) En bloc and standard esophagectomies by thoracoscopy. Ann Thorac Surg 56:675–679PubMedCrossRef
3.
Zurück zum Zitat Millikan KW, Silverstein J, Hart V, Blair K, Bines S, Roberts J, Doolas A (1995) A 15-year review of esophagectomy for carcinoma of the esophagus and cardia. Arch Surg 130:617–624PubMedCrossRef Millikan KW, Silverstein J, Hart V, Blair K, Bines S, Roberts J, Doolas A (1995) A 15-year review of esophagectomy for carcinoma of the esophagus and cardia. Arch Surg 130:617–624PubMedCrossRef
4.
Zurück zum Zitat Orringer MB, Marshall B, Chang AC, Lee J, Pickens A, Lau CL (2007) Two thousand transhiatal esophagectomies: changing trends, lessons learned. Ann Surg 246:363–372 (discussion 372–364)PubMedCrossRef Orringer MB, Marshall B, Chang AC, Lee J, Pickens A, Lau CL (2007) Two thousand transhiatal esophagectomies: changing trends, lessons learned. Ann Surg 246:363–372 (discussion 372–364)PubMedCrossRef
5.
Zurück zum Zitat Brooks JA, Kesler KA, Johnson CS, Ciaccia D, Brown JW (2002) Prospective analysis of quality of life after surgical resection for esophageal cancer: preliminary results. J Surg Oncol 81:185–194PubMedCrossRef Brooks JA, Kesler KA, Johnson CS, Ciaccia D, Brown JW (2002) Prospective analysis of quality of life after surgical resection for esophageal cancer: preliminary results. J Surg Oncol 81:185–194PubMedCrossRef
6.
Zurück zum Zitat Ku GY, Ilson DH (2009) Role of neoadjuvant therapy for esophageal adenocarcinoma. Surg Oncol Clin N Am 18:533–546PubMedCrossRef Ku GY, Ilson DH (2009) Role of neoadjuvant therapy for esophageal adenocarcinoma. Surg Oncol Clin N Am 18:533–546PubMedCrossRef
7.
Zurück zum Zitat Lv J, Cao XF, Zhu B, Ji L, Tao L, Wang DD (2009) Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma. World J Gastroenterol 15:4962–4968PubMedCrossRef Lv J, Cao XF, Zhu B, Ji L, Tao L, Wang DD (2009) Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma. World J Gastroenterol 15:4962–4968PubMedCrossRef
8.
Zurück zum Zitat Roof KS, Coen J, Lynch TJ, Wright C, Fidias P, Willett CG, Choi NC (2006) Concurrent cisplatin, 5-FU, paclitaxel, and radiation therapy in patients with locally advanced esophageal cancer. Int J Radiat Oncol Biol Phys 65:1120–1128PubMedCrossRef Roof KS, Coen J, Lynch TJ, Wright C, Fidias P, Willett CG, Choi NC (2006) Concurrent cisplatin, 5-FU, paclitaxel, and radiation therapy in patients with locally advanced esophageal cancer. Int J Radiat Oncol Biol Phys 65:1120–1128PubMedCrossRef
9.
Zurück zum Zitat Butler N, Collins S, Memon B, Memon MA (2011) Minimally invasive oesophagectomy: current status and future direction. Surg Endosc 25:2071–2083PubMedCrossRef Butler N, Collins S, Memon B, Memon MA (2011) Minimally invasive oesophagectomy: current status and future direction. Surg Endosc 25:2071–2083PubMedCrossRef
10.
Zurück zum Zitat Biere SS, Cuesta MA, van der Peet DL (2009) Minimally invasive versus open esophagectomy for cancer: a systematic review and meta-analysis. Minerva Chir 64:121–133PubMed Biere SS, Cuesta MA, van der Peet DL (2009) Minimally invasive versus open esophagectomy for cancer: a systematic review and meta-analysis. Minerva Chir 64:121–133PubMed
11.
Zurück zum Zitat Sgourakis G, Gockel I, Radtke A, Musholt TJ, Timm S, Rink A, Tsiamis A, Karaliotas C, Lang H (2010) Minimally invasive versus open esophagectomy: meta-analysis of outcomes. Dig Dis Sci 55:3031–3040PubMedCrossRef Sgourakis G, Gockel I, Radtke A, Musholt TJ, Timm S, Rink A, Tsiamis A, Karaliotas C, Lang H (2010) Minimally invasive versus open esophagectomy: meta-analysis of outcomes. Dig Dis Sci 55:3031–3040PubMedCrossRef
12.
Zurück zum Zitat Ben-David K, Sarosi GA, Cendan JC, Hochwald SN (2010) Technique of minimally invasive Ivor Lewis esophagogastrectomy with intrathoracic stapled side-to-side anastomosis. J Gastrointest Surg 14:1613–1618PubMedCrossRef Ben-David K, Sarosi GA, Cendan JC, Hochwald SN (2010) Technique of minimally invasive Ivor Lewis esophagogastrectomy with intrathoracic stapled side-to-side anastomosis. J Gastrointest Surg 14:1613–1618PubMedCrossRef
13.
Zurück zum Zitat DePaula AL, Hashiba K, Ferreira EA, de Paula RA, Grecco E (1995) Laparoscopic transhiatal esophagectomy with esophagogastroplasty. Surg Laparosc Endosc 5:1–5PubMed DePaula AL, Hashiba K, Ferreira EA, de Paula RA, Grecco E (1995) Laparoscopic transhiatal esophagectomy with esophagogastroplasty. Surg Laparosc Endosc 5:1–5PubMed
14.
Zurück zum Zitat Luketich JD, Alvelo-Rivera M, Buenaventura PO, Christie NA, McCaughan JS, Litle VR, Schauer PR, Close JM, Fernando HC (2003) Minimally invasive esophagectomy: outcomes in 222 patients. Ann Surg 238:486–494 (discussion 494–485)PubMed Luketich JD, Alvelo-Rivera M, Buenaventura PO, Christie NA, McCaughan JS, Litle VR, Schauer PR, Close JM, Fernando HC (2003) Minimally invasive esophagectomy: outcomes in 222 patients. Ann Surg 238:486–494 (discussion 494–485)PubMed
15.
Zurück zum Zitat Swanstrom LL (2002) Minimally invasive surgical approaches to esophageal cancer. J Gastrointest Surg 6:522–526PubMedCrossRef Swanstrom LL (2002) Minimally invasive surgical approaches to esophageal cancer. J Gastrointest Surg 6:522–526PubMedCrossRef
16.
Zurück zum Zitat Rice TW (2006) Pro: esophagectomy is the treatment of choice for high-grade dysplasia in Barrett’s esophagus. Am J Gastroenterol 101:2177–2179PubMedCrossRef Rice TW (2006) Pro: esophagectomy is the treatment of choice for high-grade dysplasia in Barrett’s esophagus. Am J Gastroenterol 101:2177–2179PubMedCrossRef
17.
Zurück zum Zitat Siewert JR, Lordick F, Ott K, Stein HJ, Weber WA, Becker K, Peschel C, Fink U, Schwaiger M (2007) Induction chemotherapy in Barrett cancer: influence on surgical risk and outcome. Ann Surg 246:624–628 (discussion 628–631)PubMedCrossRef Siewert JR, Lordick F, Ott K, Stein HJ, Weber WA, Becker K, Peschel C, Fink U, Schwaiger M (2007) Induction chemotherapy in Barrett cancer: influence on surgical risk and outcome. Ann Surg 246:624–628 (discussion 628–631)PubMedCrossRef
18.
Zurück zum Zitat Ben-David K, Rossidis G, Zlotecki RA, Grobmyer SR, Cendan JC, Sarosi GA, Hochwald SN (2011) Minimally invasive esophagectomy is safe and effective following neoadjuvant chemoradiation therapy. Ann Surg Oncol. Apr 9. [Epub ahead of print] Ben-David K, Rossidis G, Zlotecki RA, Grobmyer SR, Cendan JC, Sarosi GA, Hochwald SN (2011) Minimally invasive esophagectomy is safe and effective following neoadjuvant chemoradiation therapy. Ann Surg Oncol. Apr 9. [Epub ahead of print]
19.
Zurück zum Zitat Lopes J, Hochwald SN, Lancia N, Dixon LR, Ben-David K (2010) Autoimmune esophagitis: IgG4-related tumors of the esophagus. J Gastrointest Surg 14:1031–1034PubMedCrossRef Lopes J, Hochwald SN, Lancia N, Dixon LR, Ben-David K (2010) Autoimmune esophagitis: IgG4-related tumors of the esophagus. J Gastrointest Surg 14:1031–1034PubMedCrossRef
20.
Zurück zum Zitat Rossidis G, Kissane N, Hochwald SN, Zingarelli W, Sarosi GA, Ben-David K (2011) Overcoming challenges in implementing a minimally invasive esophagectomy program at a Veterans Administration Medical Center. Am J Surg. May 10. [Epub ahead of print] Rossidis G, Kissane N, Hochwald SN, Zingarelli W, Sarosi GA, Ben-David K (2011) Overcoming challenges in implementing a minimally invasive esophagectomy program at a Veterans Administration Medical Center. Am J Surg. May 10. [Epub ahead of print]
21.
Zurück zum Zitat Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE (2009) Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol 27:5062–5067PubMedCrossRef Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE (2009) Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol 27:5062–5067PubMedCrossRef
22.
Zurück zum Zitat Juergens RA, Forastiere A (2008) Combined modality therapy of esophageal cancer. J Natl Compr Canc Netw 6:851–860 (quiz 861)PubMed Juergens RA, Forastiere A (2008) Combined modality therapy of esophageal cancer. J Natl Compr Canc Netw 6:851–860 (quiz 861)PubMed
23.
Zurück zum Zitat Birkmeyer JD, Stukel TA, Siewers AE, Goodney PP, Wennberg DE, Lucas FL (2003) Surgeon volume and operative mortality in the United States. N Engl J Med 349:2117–2127PubMedCrossRef Birkmeyer JD, Stukel TA, Siewers AE, Goodney PP, Wennberg DE, Lucas FL (2003) Surgeon volume and operative mortality in the United States. N Engl J Med 349:2117–2127PubMedCrossRef
24.
Zurück zum Zitat Boudourakis LD, Wang TS, Roman SA, Desai R, Sosa JA (2009) Evolution of the surgeon-volume, patient-outcome relationship. Ann Surg 250:159–165PubMedCrossRef Boudourakis LD, Wang TS, Roman SA, Desai R, Sosa JA (2009) Evolution of the surgeon-volume, patient-outcome relationship. Ann Surg 250:159–165PubMedCrossRef
25.
Zurück zum Zitat Eloubeidi MA, Mason AC, Desmond RA, El-Serag HB (2003) Temporal trends (1973–1997) in survival of patients with esophageal adenocarcinoma in the United States: a glimmer of hope? Am J Gastroenterol 98:1627–1633PubMed Eloubeidi MA, Mason AC, Desmond RA, El-Serag HB (2003) Temporal trends (1973–1997) in survival of patients with esophageal adenocarcinoma in the United States: a glimmer of hope? Am J Gastroenterol 98:1627–1633PubMed
26.
Zurück zum Zitat Pohl H, Welch HG (2005) The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 97:142–146PubMedCrossRef Pohl H, Welch HG (2005) The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 97:142–146PubMedCrossRef
27.
Zurück zum Zitat Forman D (2005) Re: the role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 97:1013–1014 (author reply 1014)PubMedCrossRef Forman D (2005) Re: the role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 97:1013–1014 (author reply 1014)PubMedCrossRef
28.
Zurück zum Zitat Merry AH, Schouten LJ, Goldbohm RA, van den Brandt PA (2007) Body mass index, height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study. Gut 56:1503–1511PubMedCrossRef Merry AH, Schouten LJ, Goldbohm RA, van den Brandt PA (2007) Body mass index, height and risk of adenocarcinoma of the oesophagus and gastric cardia: a prospective cohort study. Gut 56:1503–1511PubMedCrossRef
29.
Zurück zum Zitat Falk J, Carstens H, Lundell L, Albertsson M (2007) Incidence of carcinoma of the oesophagus and gastric cardia. Changes over time and geographical differences. Acta Oncol 46:1070–1074PubMedCrossRef Falk J, Carstens H, Lundell L, Albertsson M (2007) Incidence of carcinoma of the oesophagus and gastric cardia. Changes over time and geographical differences. Acta Oncol 46:1070–1074PubMedCrossRef
30.
Zurück zum Zitat Bashash M, Shah A, Hislop G, Brooks-Wilson A, Le N, Bajdik C (2008) Incidence and survival for gastric and esophageal cancer diagnosed in British Columbia, 1990 to 1999. Can J Gastroenterol 22:143–148PubMed Bashash M, Shah A, Hislop G, Brooks-Wilson A, Le N, Bajdik C (2008) Incidence and survival for gastric and esophageal cancer diagnosed in British Columbia, 1990 to 1999. Can J Gastroenterol 22:143–148PubMed
31.
Zurück zum Zitat Wouters MW, Karim-Kos HE, le Cessie S, Wijnhoven BP, Stassen LP, Steup WH, Tilanus HW, Tollenaar RA (2009) Centralization of esophageal cancer surgery: does it improve clinical outcome? Ann Surg Oncol 16:1789–1798PubMedCrossRef Wouters MW, Karim-Kos HE, le Cessie S, Wijnhoven BP, Stassen LP, Steup WH, Tilanus HW, Tollenaar RA (2009) Centralization of esophageal cancer surgery: does it improve clinical outcome? Ann Surg Oncol 16:1789–1798PubMedCrossRef
32.
Zurück zum Zitat Wouters MW, Krijnen P, Le Cessie S, Gooiker GA, Guicherit OR, Marinelli AW, Kievit J, Tollenaar RA (2009) Volume- or outcome-based referral to improve quality of care for esophageal cancer surgery in The Netherlands. J Surg Oncol 99:481–487PubMedCrossRef Wouters MW, Krijnen P, Le Cessie S, Gooiker GA, Guicherit OR, Marinelli AW, Kievit J, Tollenaar RA (2009) Volume- or outcome-based referral to improve quality of care for esophageal cancer surgery in The Netherlands. J Surg Oncol 99:481–487PubMedCrossRef
33.
Zurück zum Zitat Rindani R, Martin CJ, Cox MR (1999) Transhiatal versus Ivor-Lewis oesophagectomy: is there a difference? Aust N Z J Surg 69:187–194PubMedCrossRef Rindani R, Martin CJ, Cox MR (1999) Transhiatal versus Ivor-Lewis oesophagectomy: is there a difference? Aust N Z J Surg 69:187–194PubMedCrossRef
34.
Zurück zum Zitat Yamasaki M, Miyata H, Fujiwara Y, Takiguchi S, Nakajima K, Kurokawa Y, Mori M, Doki Y (2011) Minimally invasive esophagectomy for esophageal cancer: comparative analysis of open and hand-assisted laparoscopic abdominal lymphadenectomy with gastric conduit reconstruction. J Surg Oncol. doi:10.1002/jso.21991 Yamasaki M, Miyata H, Fujiwara Y, Takiguchi S, Nakajima K, Kurokawa Y, Mori M, Doki Y (2011) Minimally invasive esophagectomy for esophageal cancer: comparative analysis of open and hand-assisted laparoscopic abdominal lymphadenectomy with gastric conduit reconstruction. J Surg Oncol. doi:10.​1002/​jso.​21991
35.
Zurück zum Zitat Singh RK, Pham TH, Diggs BS, Perkins S, Hunter JG (2011) Minimally invasive esophagectomy provides equivalent oncologic outcomes to open esophagectomy for locally advanced (stage II or III) esophageal carcinoma. Arch Surg 146:711–714PubMedCrossRef Singh RK, Pham TH, Diggs BS, Perkins S, Hunter JG (2011) Minimally invasive esophagectomy provides equivalent oncologic outcomes to open esophagectomy for locally advanced (stage II or III) esophageal carcinoma. Arch Surg 146:711–714PubMedCrossRef
36.
Zurück zum Zitat Berger AC, Bloomenthal A, Weksler B, Evans N, Chojnacki KA, Yeo CJ, Rosato EL (2011) Oncologic efficacy is not compromised, and may be improved with minimally invasive esophagectomy. J Am Coll Surg 212:560–566 (discussion 566–568)PubMedCrossRef Berger AC, Bloomenthal A, Weksler B, Evans N, Chojnacki KA, Yeo CJ, Rosato EL (2011) Oncologic efficacy is not compromised, and may be improved with minimally invasive esophagectomy. J Am Coll Surg 212:560–566 (discussion 566–568)PubMedCrossRef
Metadaten
Titel
Decreasing morbidity and mortality in 100 consecutive minimally invasive esophagectomies
verfasst von
Kfir Ben-David
George A. Sarosi
Juan C. Cendan
Drew Howard
Georgios Rossidis
Steven N. Hochwald
Publikationsdatum
01.01.2012
Verlag
Springer-Verlag
Erschienen in
Surgical Endoscopy / Ausgabe 1/2012
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-011-1846-3

Weitere Artikel der Ausgabe 1/2012

Surgical Endoscopy 1/2012 Zur Ausgabe

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

23.04.2024 Ablationstherapie Nachrichten

Nach der Katheterablation von Vorhofflimmern kommt es bei etwa einem Drittel der Patienten zu Rezidiven, meist binnen eines Jahres. Wie sich spätere Rückfälle auf die Erfolgschancen einer erneuten Ablation auswirken, haben Schweizer Kardiologen erforscht.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

23.04.2024 Operationsvorbereitung Nachrichten

Derzeit wird empfohlen, eine Therapie mit GLP-1-Rezeptoragonisten präoperativ zu unterbrechen. Eine neue Studie nährt jedoch Zweifel an der Notwendigkeit der Maßnahme.

Ureterstriktur: Innovative OP-Technik bewährt sich

19.04.2024 EAU 2024 Kongressbericht

Die Ureterstriktur ist eine relativ seltene Komplikation, trotzdem bedarf sie einer differenzierten Versorgung. In komplexen Fällen wird dies durch die roboterassistierte OP-Technik gewährleistet. Erste Resultate ermutigen.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.