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01.03.2005 | Review

Impact of inflammation and oxidative stress on vascular calcifications in chronic kidney disease

verfasst von: Z. A. Massy, C. Mazière, S. Kamel, M. Brazier, G. Choukroun, C. Tribouilloy, M. Slama, M. Andrejak, J. C. Mazière

Erschienen in: Pediatric Nephrology | Ausgabe 3/2005

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Abstract

Vascular and/or valvular calcifications in patients with chronic kidney disease (CKD) appear to indicate a poor prognosis in terms of overall survival and cardiovascular morbidity and mortality. Inflammation and oxidative stress represent new features of the arterial and/or valvular calcification process. However, only limited observational and epidemiological data are available in these areas. Therefore, the link between inflammation, oxidation and vascular and/or valvular calcifications deserves careful consideration in CKD patients, since they may become targets for the development of new therapeutic strategies.

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Titel: Impact of inflammation and oxidative stress on vascular calcifications in chronic kidney disease
verfasst von: Z. A. Massy
C. Mazière
S. Kamel
M. Brazier
G. Choukroun
C. Tribouilloy
M. Slama
M. Andrejak
J. C. Mazière
Publikationsdatum: 01.03.2005
Verlag: Springer-Verlag
Erschienen in: Pediatric Nephrology / Ausgabe 3/2005
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-004-1623-9

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