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Pediatric Nephrology

Erschienen in:

30.11.2016 | Review

The role of fluid overload in the prediction of outcome in acute kidney injury

verfasst von: David T Selewski, Stuart L Goldstein

Erschienen in: Pediatric Nephrology | Ausgabe 1/2018

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Abstract

Our understanding of the epidemiology and the impact of acute kidney injury (AKI) and fluid overload on outcomes has improved significantly over the past several decades. Fluid overload occurs commonly in critically ill children with and without associated AKI. Researchers in pediatric AKI have been at the forefront of describing the impact of fluid overload on outcomes in a variety of populations. A full understanding of this topic is important as fluid overload represents a potentially modifiable risk factor and a target for intervention. In this state-of-the-art review, we comprehensively describe the definition of fluid overload, the impact of fluid overload on kidney function, the impact of fluid overload on the diagnosis of AKI, the association of fluid overload with outcomes, the targeted therapy of fluid overload, and the impact of the timing of renal replacement therapy on outcomes.

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Titel: The role of fluid overload in the prediction of outcome in acute kidney injury
verfasst von: David T Selewski
Stuart L Goldstein
Publikationsdatum: 30.11.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 1/2018
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-016-3539-6

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