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Erschienen in: Archives of Virology 6/2017

15.02.2017 | Brief Report

Genotype analysis of ORF 62 identifies varicella-zoster virus infections caused by a vaccine strain in children

verfasst von: Byung Ok Kwak, Hoan Jong Lee, Hyun Mi Kang, Chi Eun Oh, Eun Hwa Choi

Erschienen in: Archives of Virology | Ausgabe 6/2017

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Abstract

This study was performed to differentiate vaccine-type strains from wild-type strains and determine the genotype of varicella-zoster virus (VZV) in 51 Korean children. A sequencing analysis of ORF 62 identified two cases of herpes zoster caused by the vaccine-type virus, without a previous history of varicella, 22 months and 5 months after VZV vaccination. The wild-type strain was identified in the remaining children. A genotype analysis of ORF 22 amino acids revealed genotype J in all children except one. Genotype E was identified in an infant with varicella imported from Egypt.
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Metadaten
Titel
Genotype analysis of ORF 62 identifies varicella-zoster virus infections caused by a vaccine strain in children
verfasst von
Byung Ok Kwak
Hoan Jong Lee
Hyun Mi Kang
Chi Eun Oh
Eun Hwa Choi
Publikationsdatum
15.02.2017
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 6/2017
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-017-3276-6

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