nach oben

European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

01.06.2012 | Article

Detection of three human adenovirus species in adults with acute respiratory infection in China

verfasst von: L. Guo, R. Gonzalez, H. Zhou, C. Wu, G. Vernet, Z. Wang, J. Wang

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 6/2012

Einloggen, um Zugang zu erhalten

Abstract

Human adenoviruses (HAdVs) are recognized as causal agents in a wide range of human diseases. However, researchers lack sufficient data on the exact HAdV species and serotypes associated with adult acute respiratory tract infections (ARTIs). To detect and characterize HAdV infections in adults in China, clinical specimens were collected from 10,310 adults with ARTIs from May 2005 to July 2010. The partial HAdV hexon gene was amplified by polymerase chain reaction (PCR), sequenced, and phylogenetically analyzed. HAdVs were detected in 86 samples (0.8%), of which 67 (77.9%) were species B (HAdV-3, -7, -11, and -14), 7 (8.1%) were species C (HAdV-1, -2, and -6), and 12 (14%) were species E (HAdV-4). HAdV-3 was the most frequently detected serotype (41/86, 47.7%), followed by HAdV-7 (13/86, 15.1%), HAdV-4 (12/86, 14.0%), and HAdV-11 (11/86, 12.8%). Patients 14–25 years old (60.5%) exhibited a higher rate of adenovirus detection than older patients. Co-infections with other respiratory viruses were observed in samples positive for HAdV species B and E. Human rhinovirus was the most commonly found virus in patients with HAdV infection. These findings provide baseline data for the surveillance and control of HAdV infection in China.

Jones MS 2nd, Harrach B, Ganac RD, Gozum MM, Dela Cruz WP, Riedel B, Pan C, Delwart EL, Schnurr DP (2007) New adenovirus species found in a patient presenting with gastroenteritis. J Virol 81:5978–5984PubMedCrossRef

Robinson CM, Singh G, Henquell C, Walsh MP, Peigue-Lafeuille H, Seto D, Jones MS, Dyer DW, Chodosh J (2011) Computational analysis and identification of an emergent human adenovirus pathogen implicated in a respiratory fatality. Virology 409:141–147PubMedCrossRef

Shenk T (2001) Adenoviridae: the viruses and their replication. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (eds) Fundamental virology. Lippincott Williams & Wilkins, Baltimore, pp 1053–1088

Davison AJ, Benko M, Harrach B (2003) Genetic content and evolution of adenoviruses. J Gen Virol 84:2895–2908PubMedCrossRef

Louie JK, Kajon AE, Holodniy M, Guardia-LaBar L, Lee B, Petru AM, Hacker JK, Schnurr DP (2008) Severe pneumonia due to adenovirus serotype 14: a new respiratory threat? Clin Infect Dis 146:421–425CrossRef

Echavarria M, Sanchez JL, Kolavic-Gray SA, Polyak CS, Mitchell-Raymundo F, Innis BL, Vaughn D, Reynolds R, Binn LN (2003) Rapid detection of adenovirus in throat swab specimens by PCR during respiratory disease outbreaks among military recruits. J Clin Microbiol 41:810–812PubMedCrossRef

Metzgar D, Osuna M, Kajon AE, Hawksworth AW, Irvine M, Russell KL (2007) Abrupt emergence of diverse species B adenoviruses at US military recruit training centers. J Infect Dis 196:1465–1473PubMedCrossRef

Washington C, Metzgar D, Hazbón MH, Binn L, Lyons A, Coward C, Kuschner R (2010) Multiplexed Luminex xMAP assay for detection and identification of five adenovirus serotypes associated with epidemics of respiratory disease in adults. J Clin Microbiol 48:2217–2222PubMedCrossRef

Schmitz H, Wigand R, Heinrich W (1983) Worldwide epidemiology of human adenovirus infections. Am J Epidemiol 117:455–466PubMed

10.

Li QG, Zheng QJ, Liu YH, Wadell G (1996) Molecular epidemiology of adenovirus types 3 and 7 isolated from children with pneumonia in Beijing. J Med Virol 49:170–177PubMedCrossRef

11.

Zhang Q, Su X, Gong S, Zeng Q, Zhu B, Wu Z, Peng T, Zhang C, Zhou R (2006) Comparative genomic analysis of two strains of human adenovirus type 3 isolated from children with acute respiratory infection in southern China. J Gen Virol 87:1531–1541PubMedCrossRef

12.

Ou ZY, Zeng QY, Wang FH, Xia HM, Lu JP, Xia JQ, Gong ST, Deng L, Zhang JT, Zhou R (2008) Retrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China. BMC Infect Dis 8:122PubMedCrossRef

13.

Peng D, Zhao D, Liu J, Wang X, Yang K, Xicheng H, Li Y, Wang F (2009) Multipathogen infections in hospitalized children with acute respiratory infections. Virol J 6:155PubMedCrossRef

14.

Zhang HY, Li ZM, Zhang GL, Diao TT, Cao CX, Sun HQ (2009) Respiratory viruses in hospitalized children with acute lower respiratory tract infections in Harbin, China. Jpn J Infect Dis 62:458–460PubMed

15.

Wang W, Cavailler P, Ren P, Zhang J, Dong W, Yan H, Mardy S, Cailhol J, Buchy P, Sheng J, Fontanet A, Deubel V (2010) Molecular monitoring of causative viruses in child acute respiratory infection in endemo-epidemic situations in Shanghai. J Clin Virol 49:211–218PubMedCrossRef

16.

Kajon AE, Moseley JM, Metzgar D, Huong HS, Wadleigh A, Ryan MA, Russell KL (2007) Molecular epidemiology of adenovirus type 4 infections in US military recruits in the postvaccination era (1997–2003). J Infect Dis 196:67–75PubMedCrossRef

17.

Ren L, Gonzalez R, Wang Z, Xiang Z, Wang Y, Zhou H, Li J, Xiao Y, Yang Q, Zhang J, Chen L, Wang W, Li Y, Li T, Meng X, Zhang Y, Vernet G, Paranhos-Baccalà G, Chen J, Jin Q, Wang J (2009) Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005–2007. Clin Microbiol Infect 15:1146–1153PubMedCrossRef

18.

Allard A, Albinsson B, Wadell G (2001) Rapid typing of human adenoviruses by a general PCR combined with restriction endonuclease analysis. J Clin Microbiol 39:498–505PubMedCrossRef

19.

Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599PubMedCrossRef

20.

Cooper RJ, Hallett R, Tullo AB, Klapper PE (2000) The epidemiology of adenovirus infections in Greater Manchester, UK 1982–96. Epidemiol Infect 125:333–345PubMedCrossRef

21.

Zhu Z, Zhang Y, Xu S, Yu P, Tian X, Wang L, Liu Z, Tang L, Mao N, Ji Y, Li C, Yang Z, Wang S, Wang J, Li D, Xu W (2009) Outbreak of acute respiratory disease in China caused by B2 species of adenovirus type 11. J Clin Microbiol 47:697–703PubMedCrossRef

22.

Abd-Jamil J, Teoh BT, Hassan EH, Roslan N, Abubakar S (2010) Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center. BMC Pediatr 10:46PubMedCrossRef

23.

Hong JY, Lee HJ, Piedra PA, Choi EH, Park KH, Koh YY, Kim WS (2001) Lower respiratory tract infections due to adenovirus in hospitalized Korean children: epidemiology, clinical features, and prognosis. Clin Infect Dis 32:1423–1429PubMedCrossRef

24.

Ren L, Gonzalez R, Xu J, Xiao Y, Li Y, Zhou H, Li J, Yang Q, Zhang J, Chen L, Wang W, Vernet G, Paranhos-Baccalà G, Wang Z, Wang J (2011) Prevalence of human coronaviruses in adults with acute respiratory tract infections in Beijing, China. J Med Virol 83:291–297PubMedCrossRef

25.

Nokes DJ, Ngama M, Bett A, Abwao J, Munywoki P, English M, Scott JA, Cane PA, Medley GF (2009) Incidence and severity of respiratory syncytial virus pneumonia in rural Kenyan children identified through hospital surveillance. Clin Infect Dis 49:1341–1349PubMedCrossRef

26.

Yeung R, Eshaghi A, Lombos E, Blair J, Mazzulli T, Burton L, Drews SJ (2009) Characterization of culture-positive adenovirus serotypes from respiratory specimens in Toronto, Ontario, Canada: September 2007–June 2008. Virol J 6:11PubMedCrossRef

27.

Lin YC, Lin KH, Ke GM, Lee MS, Lin PC, Liu HF, Hsu LC, Lu PL (2010) Secular trend of genome types of respiratory adenovirus type 3 during 1983–2005: a study from Taiwan. Arch Virol 155:287–292PubMedCrossRef

28.

Tate JE, Bunning ML, Lott L, Lu X, Su J, Metzgar D, Brosch L, Panozzo CA, Marconi VC, Faix DJ, Prill M, Johnson B, Erdman DD, Fonseca V, Anderson LJ, Widdowson MA (2009) Outbreak of severe respiratory disease associated with emergent human adenovirus serotype 14 at a US air force training facility in 2007. J Infect Dis 199:1419–1426PubMedCrossRef

29.

Saitoh-Inagawa W, Aoki K, Uchio E, Itoh N, Ohno S (1999) Ten years’ surveillance of viral conjunctivitis in Sapporo, Japan. Graefes Arch Clin Exp Ophthalmol 237:35–38PubMedCrossRef

Titel: Detection of three human adenovirus species in adults with acute respiratory infection in China
verfasst von: L. Guo
R. Gonzalez
H. Zhou
C. Wu
G. Vernet
Z. Wang
J. Wang
Publikationsdatum: 01.06.2012
Verlag: Springer-Verlag
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 6/2012
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-011-1406-8

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

25.04.2024 Allergien und Intoleranzreaktionen Nachrichten

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 6/2012

Evaluation of the Determine Syphilis TP assay for the detection of antibodies against Treponema pallidum for the serodiagnosis of syphilis

Mycobacterial infections in adult patients with hematological malignancy

Evaluation of species-specific score cutoff values of routinely isolated clinically relevant bacteria using a direct smear preparation for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based bacterial identification

Evidence of significant synergism between antibiotics and the antipsychotic, antimicrobial drug flupenthixol

Comparison of the Etest and a rapid flow cytometry-based method with the reference CLSI broth microdilution protocol M27-A3 for the echinocandin susceptibility testing of Candida spp.

Differentiation between Shigella, enteroinvasive Escherichia coli (EIEC) and noninvasive Escherichia coli