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Neurosurgical Review

Erschienen in:

16.01.2022 | Review

Traumatic optic neuropathy: a review of current studies

verfasst von: Bin Chen, Hengsen Zhang, Qing Zhai, Huaipeng Li, Chunxia Wang, Yong Wang

Erschienen in: Neurosurgical Review | Ausgabe 3/2022

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Abstract

Traumatic optic neuropathy (TON) is a serious complication of craniofacial trauma that directly or indirectly damages the optic nerve and can cause severe vision loss. The incidence of TON has been gradually increasing in recent years. Research on the protection and regeneration of the optic nerve after the onset of TON is still at the level of laboratory studies and which is insufficient to support clinical treatment of TON. And, due to without clear guidelines, there is much ambiguity regarding its diagnosis and management. Clinical interventions for TON include observation only, treatment with corticosteroids alone, or optic canal (OC) decompression (with or without steroids). There is controversy in clinical practice concerning which treatment is the best. A review of available studies shows that the visual acuity of patients with TON can be significantly improved after OC decompression surgery (especially endoscopic transnasal/transseptal optic canal decompression (ETOCD)) with or without the use of corticosteroids. And new findings of laboratory studies such as mitochondrial therapy, lipid change studies, and other studies in favor of TON therapy have also been identified. In this review, we discuss the evolving perspective of surgical treatment and experimental study.

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Titel: Traumatic optic neuropathy: a review of current studies
verfasst von: Bin Chen
Hengsen Zhang
Qing Zhai
Huaipeng Li
Chunxia Wang
Yong Wang
Publikationsdatum: 16.01.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Neurosurgical Review / Ausgabe 3/2022
Print ISSN: 0344-5607
Elektronische ISSN: 1437-2320
DOI: https://doi.org/10.1007/s10143-021-01717-9

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