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Erschienen in: Techniques in Coloproctology 4/2018

22.03.2018 | Original Article

Transanal total mesorectal excision for rectal cancer: evaluation of the learning curve

verfasst von: T. W. A. Koedam, M. Veltcamp Helbach, P. M. van de Ven, Ph. M. Kruyt, N. T. van Heek, H. J. Bonjer, J. B. Tuynman, C. Sietses

Erschienen in: Techniques in Coloproctology | Ausgabe 4/2018

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Abstract

Background

Transanal total mesorectal excision (TaTME) provides an excellent view of the resection margins for rectal cancer from below, but is challenging due to few anatomical landmarks. During implementation of this technique, patient safety and optimal outcomes need to be ensured. The aim of this study was to evaluate the learning curve of TaTME in patients with rectal cancer in order to optimize future training programs.

Methods

All consecutive patients after TaTME for rectal cancer between February 2012 and January 2017 were included in a single-center database. Influence of surgical experience on major postoperative complications, leakage rate and operating time was evaluated using cumulative sum charts and the splitting model. Correction for potential case-mix differences was performed.

Results

Over a period of 60 months, a total of 138 patients were included in this study. Adjusted for case-mix, improvement in postoperative outcomes was clearly seen after the first 40 patients, showing a decrease in major postoperative complications from 47.5 to 17.5% and leakage rate from 27.5 to 5%. Mean operating time (42 min) and conversion rate (from 10% to zero) was lower after transition to a two-team approach, but neither endpoint decreased with experience. Readmission and reoperation rates were not influenced by surgical experience.

Conclusions

The learning curve of TaTME affected major (surgical) postoperative complications for the first 40 patients. A two-team approach decreased operative time and conversion rate. When implementing this new technique, a thorough teaching and supervisory program is recommended to shorten the learning curve and improve the clinical outcomes of the first patients.
Literatur
1.
Zurück zum Zitat Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482CrossRefPubMed Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482CrossRefPubMed
2.
Zurück zum Zitat Kapiteijn E, Marijnen CA, Nagtegaal ID et al (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638–646CrossRefPubMed Kapiteijn E, Marijnen CA, Nagtegaal ID et al (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638–646CrossRefPubMed
3.
Zurück zum Zitat MacFarlane JK, Ryall RD, Heald RJ (1993) Mesorectal excision for rectal cancer. Lancet 341:457–460CrossRefPubMed MacFarlane JK, Ryall RD, Heald RJ (1993) Mesorectal excision for rectal cancer. Lancet 341:457–460CrossRefPubMed
4.
Zurück zum Zitat Bonjer HJ, Deijen CL, Abis GA et al (2015) A randomized trial of laparoscopic versus open surgery for rectal cancer (COLOR II trial). N Engl J Med 372:1324–1332CrossRefPubMed Bonjer HJ, Deijen CL, Abis GA et al (2015) A randomized trial of laparoscopic versus open surgery for rectal cancer (COLOR II trial). N Engl J Med 372:1324–1332CrossRefPubMed
5.
Zurück zum Zitat Jeong SY, Park JW, Nam BH et al (2014) Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial. Lancet Oncol 15:767–774CrossRefPubMed Jeong SY, Park JW, Nam BH et al (2014) Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial. Lancet Oncol 15:767–774CrossRefPubMed
6.
Zurück zum Zitat Green BL, Marshall HC, Collinson F et al (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100:75–82CrossRefPubMed Green BL, Marshall HC, Collinson F et al (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100:75–82CrossRefPubMed
7.
Zurück zum Zitat Van der Pas MHGM, Deijen CL, Abis GA et al (2017) Conversions in laparoscopic surgery for rectal cancer. Surg Endosc 31:2263–2270CrossRefPubMed Van der Pas MHGM, Deijen CL, Abis GA et al (2017) Conversions in laparoscopic surgery for rectal cancer. Surg Endosc 31:2263–2270CrossRefPubMed
8.
Zurück zum Zitat Lacy AM, Rattner DW, Adelsdorfer C et al (2013) Transanal natural orifice transluminal endoscopic surgery (NOTES) rectal resection: “down-to up” total mesorectal excision (TME)—short-term outcomes in the first 20 cases. Surg Endosc 27:3165–3172CrossRefPubMed Lacy AM, Rattner DW, Adelsdorfer C et al (2013) Transanal natural orifice transluminal endoscopic surgery (NOTES) rectal resection: “down-to up” total mesorectal excision (TME)—short-term outcomes in the first 20 cases. Surg Endosc 27:3165–3172CrossRefPubMed
9.
Zurück zum Zitat Lacy AM, Tasende MM, Delgado S et al (2015) Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients. J Am Coll Surg 221:415–423CrossRefPubMed Lacy AM, Tasende MM, Delgado S et al (2015) Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients. J Am Coll Surg 221:415–423CrossRefPubMed
10.
Zurück zum Zitat Veltcamp Helbach M, Deijen CL, Velthuis S et al (2016) Transanal total mesorectal excision for rectal carcinoma: short-term outcomes and experience after 80 cases. Surg Endosc 30(2):464–470CrossRefPubMed Veltcamp Helbach M, Deijen CL, Velthuis S et al (2016) Transanal total mesorectal excision for rectal carcinoma: short-term outcomes and experience after 80 cases. Surg Endosc 30(2):464–470CrossRefPubMed
11.
Zurück zum Zitat Deijen CL, Tsai A, Koedam TW et al (2016) Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review. Tech Coloproctol 20(12):811–824CrossRefPubMedPubMedCentral Deijen CL, Tsai A, Koedam TW et al (2016) Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review. Tech Coloproctol 20(12):811–824CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Penna M, Hompes R, Arnold S et al (2017) Transanal total mesorectal excision: international registry results of the first 720 cases. Ann Surg 266(1):111–117CrossRefPubMed Penna M, Hompes R, Arnold S et al (2017) Transanal total mesorectal excision: international registry results of the first 720 cases. Ann Surg 266(1):111–117CrossRefPubMed
13.
Zurück zum Zitat Francis N, Penna M, Mackenzie H et al (2017) Consensus on structured training curriculum for transanal total mesorectal excision (TaTME). Surg Endosc 31:2711–2719CrossRefPubMed Francis N, Penna M, Mackenzie H et al (2017) Consensus on structured training curriculum for transanal total mesorectal excision (TaTME). Surg Endosc 31:2711–2719CrossRefPubMed
14.
15.
Zurück zum Zitat Bege T, Lelong B, Esterni B et al (2010) The learning curve for the laparoscopic approach to conservative mesorectal excision for rectal cancer. Ann Surg 251:249–253CrossRefPubMed Bege T, Lelong B, Esterni B et al (2010) The learning curve for the laparoscopic approach to conservative mesorectal excision for rectal cancer. Ann Surg 251:249–253CrossRefPubMed
16.
Zurück zum Zitat McArdle CS, Hole D (1991) Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 302:1501–1505CrossRefPubMedPubMedCentral McArdle CS, Hole D (1991) Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 302:1501–1505CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Martling A, Cedermark B, Johansson H et al (2002) The surgeon as a prognostic factor after the introduction of total mesorectal excision in the treatment of rectal cancer. Br J Surg 89(8):1008–1013CrossRefPubMed Martling A, Cedermark B, Johansson H et al (2002) The surgeon as a prognostic factor after the introduction of total mesorectal excision in the treatment of rectal cancer. Br J Surg 89(8):1008–1013CrossRefPubMed
20.
Zurück zum Zitat Arroyave MC, DeLacy FB, Lacy AM (2016) Transanal total mesorectal excision (TaTME) for rectal cancer: step by step description of the surgical technique for a two-teams approach. Eur J Surg Oncol 2:502–505 Arroyave MC, DeLacy FB, Lacy AM (2016) Transanal total mesorectal excision (TaTME) for rectal cancer: step by step description of the surgical technique for a two-teams approach. Eur J Surg Oncol 2:502–505
21.
Zurück zum Zitat Nagtegaal I, van de Veld CJH, van der Worp E et al (2002) Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 20:1729–1734CrossRefPubMed Nagtegaal I, van de Veld CJH, van der Worp E et al (2002) Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 20:1729–1734CrossRefPubMed
22.
Zurück zum Zitat Rahbari NN, Weitz J, Hohenberger W (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147(3):339–351CrossRefPubMed Rahbari NN, Weitz J, Hohenberger W (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147(3):339–351CrossRefPubMed
23.
Zurück zum Zitat Park EJ, Kim CW, Cho MS et al (2014) Is the learning curve of robotic low anterior resection shorter than laparoscopic low anterior resection for rectal cancer? Medicine 93(25):109CrossRef Park EJ, Kim CW, Cho MS et al (2014) Is the learning curve of robotic low anterior resection shorter than laparoscopic low anterior resection for rectal cancer? Medicine 93(25):109CrossRef
24.
Zurück zum Zitat Kim CH, Kim HJ, Huh JW et al (2014) Learning curve of laparoscopic low anterior resection in terms of local recurrence. J Surg Oncol 110:989–996CrossRefPubMed Kim CH, Kim HJ, Huh JW et al (2014) Learning curve of laparoscopic low anterior resection in terms of local recurrence. J Surg Oncol 110:989–996CrossRefPubMed
25.
Zurück zum Zitat Khan N, Abboudi H, Khan MS et al (2014) Measuring the surgical ‘learning curve’: methods, variables and competency. BJU Int 113:504–508CrossRefPubMed Khan N, Abboudi H, Khan MS et al (2014) Measuring the surgical ‘learning curve’: methods, variables and competency. BJU Int 113:504–508CrossRefPubMed
26.
Zurück zum Zitat Chen W, Sailhamer E, Berger DL et al (2007) Operative time is a poor surrogate for the learning curve in laparoscopic colorectal surgery. Surg Endosc 21:238–243CrossRefPubMed Chen W, Sailhamer E, Berger DL et al (2007) Operative time is a poor surrogate for the learning curve in laparoscopic colorectal surgery. Surg Endosc 21:238–243CrossRefPubMed
Metadaten
Titel
Transanal total mesorectal excision for rectal cancer: evaluation of the learning curve
verfasst von
T. W. A. Koedam
M. Veltcamp Helbach
P. M. van de Ven
Ph. M. Kruyt
N. T. van Heek
H. J. Bonjer
J. B. Tuynman
C. Sietses
Publikationsdatum
22.03.2018
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 4/2018
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-018-1771-8

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