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Erschienen in: Clinical and Experimental Nephrology 2/2010

01.04.2010 | Original Article

Chronic kidney disease management in an academic internal medicine clinic

verfasst von: Benjamin D. Morrow, Ian J. Stewart, Eric W. Barnes, Casey L. Cotant

Erschienen in: Clinical and Experimental Nephrology | Ausgabe 2/2010

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Abstract

Objective

We sought to evaluate the current state of chronic kidney disease (CKD) management in our academic internal medicine clinic.

Methods

A retrospective review was carried out involving all patients with laboratory evidence of CKD enrolled in our clinic. We evaluated the rate of CKD recognition as well as compliance with standard guidelines. We further subdivided our results based on physician training level, presence of diabetes, recognition of CKD, age, and race.

Results

Factors that significantly improved recognition and treatment of CKD in our study included presence of diabetes (p < 0.001), black race (p = 0.013), younger age (p = 0.004), and treatment by a resident physician (p = 0.009). Recognition of stage 3 CKD was associated with significant increases in urine protein analysis (p < 0.001) and nephrology consultation (p < 0.001).

Conclusion

Chronic kidney disease remains under-recognized and undertreated despite well-publicized guidelines and widespread use of routine eGFR reporting.
Literatur
1.
Zurück zum Zitat Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298(17):2038–47.CrossRefPubMed Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298(17):2038–47.CrossRefPubMed
2.
Zurück zum Zitat Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C-y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351(13):1296–305.CrossRefPubMed Go AS, Chertow GM, Fan D, McCulloch CE, Hsu C-y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351(13):1296–305.CrossRefPubMed
3.
Zurück zum Zitat Young JH, Klag MJ, Muntner P, Whyte JL, Pahor M, Coresh J. Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP). J Am Soc Nephrol. 2002;13(11):2776–82.CrossRefPubMed Young JH, Klag MJ, Muntner P, Whyte JL, Pahor M, Coresh J. Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP). J Am Soc Nephrol. 2002;13(11):2776–82.CrossRefPubMed
4.
Zurück zum Zitat Bakris GL, Weir MR, Shanifar S, et al. Effects of blood pressure level on progression of diabetic nephropathy: results from the RENAAL study. Arch Intern Med. 2003;163(13):1555–65.CrossRefPubMed Bakris GL, Weir MR, Shanifar S, et al. Effects of blood pressure level on progression of diabetic nephropathy: results from the RENAAL study. Arch Intern Med. 2003;163(13):1555–65.CrossRefPubMed
5.
Zurück zum Zitat Hillege HL, Fidler V, Diercks GFH, et al. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation. 2002;106(14):1777–82.CrossRefPubMed Hillege HL, Fidler V, Diercks GFH, et al. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation. 2002;106(14):1777–82.CrossRefPubMed
6.
Zurück zum Zitat Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):145–53.CrossRefPubMed Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342(3):145–53.CrossRefPubMed
7.
Zurück zum Zitat Investigators O, Yusuf S, Teo KK, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008;358(15):1547–59.CrossRef Investigators O, Yusuf S, Teo KK, et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008;358(15):1547–59.CrossRef
8.
Zurück zum Zitat Jafar TH, Stark PC, Schmid CH, et al. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med. 2003;139(4):244–52.PubMed Jafar TH, Stark PC, Schmid CH, et al. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med. 2003;139(4):244–52.PubMed
9.
Zurück zum Zitat Jones C, Roderick P, Harris S, Rogerson M. Decline in kidney function before and after nephrology referral and the effect on survival in moderate to advanced chronic kidney disease. Nephrol Dial Transplant. 2006;21(8):2133–43.CrossRefPubMed Jones C, Roderick P, Harris S, Rogerson M. Decline in kidney function before and after nephrology referral and the effect on survival in moderate to advanced chronic kidney disease. Nephrol Dial Transplant. 2006;21(8):2133–43.CrossRefPubMed
10.
Zurück zum Zitat John R, Webb M, Young A, Stevens PE. Unreferred chronic kidney disease: a longitudinal study. Am J Kidney Dis. 2004;43(5):825–35.CrossRefPubMed John R, Webb M, Young A, Stevens PE. Unreferred chronic kidney disease: a longitudinal study. Am J Kidney Dis. 2004;43(5):825–35.CrossRefPubMed
11.
Zurück zum Zitat Tseng C-L, Kern EFO, Miller DR, et al. Survival benefit of nephrologic care in patients with diabetes mellitus and chronic kidney disease. Arch Intern Med. 2008;168(1):55–62.CrossRefPubMed Tseng C-L, Kern EFO, Miller DR, et al. Survival benefit of nephrologic care in patients with diabetes mellitus and chronic kidney disease. Arch Intern Med. 2008;168(1):55–62.CrossRefPubMed
12.
Zurück zum Zitat Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461–70.PubMed Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461–70.PubMed
13.
Zurück zum Zitat Wyatt C, Konduri V, Eng J, Rohatgi R. Reporting of estimated GFR in the primary care clinic. Am J Kidney Dis. 2007;49(5):634–41.CrossRefPubMed Wyatt C, Konduri V, Eng J, Rohatgi R. Reporting of estimated GFR in the primary care clinic. Am J Kidney Dis. 2007;49(5):634–41.CrossRefPubMed
14.
Zurück zum Zitat Ryan TP, Sloand JA, Winters PC, Corsetti JP, Fisher SG. Chronic kidney disease prevalence and rate of diagnosis. Am J Med. 2007;120(11):981–6.CrossRefPubMed Ryan TP, Sloand JA, Winters PC, Corsetti JP, Fisher SG. Chronic kidney disease prevalence and rate of diagnosis. Am J Med. 2007;120(11):981–6.CrossRefPubMed
15.
Zurück zum Zitat Minutolo R, DeNicola L, Mazzaglia G, et al. Detection and awareness of moderate to advanced CKD by primary care practitioners: a cross-sectional study from Italy. Am J Kidney Dis. 2008;52(3):444–53.CrossRefPubMed Minutolo R, DeNicola L, Mazzaglia G, et al. Detection and awareness of moderate to advanced CKD by primary care practitioners: a cross-sectional study from Italy. Am J Kidney Dis. 2008;52(3):444–53.CrossRefPubMed
16.
Zurück zum Zitat Rothberg M, Kehoe E, Courtemanche A, et al. Recognition and management of chronic kidney disease in an elderly ambulatory population. J Gen Intern Med. 2008;23(8):1125–30.CrossRefPubMed Rothberg M, Kehoe E, Courtemanche A, et al. Recognition and management of chronic kidney disease in an elderly ambulatory population. J Gen Intern Med. 2008;23(8):1125–30.CrossRefPubMed
17.
Zurück zum Zitat Akbari A, Swedko PJ, Clark HD, et al. Detection of chronic kidney disease with laboratory reporting of estimated glomerular filtration rate and an educational program. Arch Intern Med. 2004;164(16):1788–92.CrossRefPubMed Akbari A, Swedko PJ, Clark HD, et al. Detection of chronic kidney disease with laboratory reporting of estimated glomerular filtration rate and an educational program. Arch Intern Med. 2004;164(16):1788–92.CrossRefPubMed
18.
Zurück zum Zitat Navaneethan SD, Nigwekar S, Sengodan M, et al. Referral to nephrologists for chronic kidney disease care: is non-diabetic kidney disease ignored? Nephron. 2007;106(3):c113–8.PubMed Navaneethan SD, Nigwekar S, Sengodan M, et al. Referral to nephrologists for chronic kidney disease care: is non-diabetic kidney disease ignored? Nephron. 2007;106(3):c113–8.PubMed
19.
Zurück zum Zitat Kinchen KS, Sadler J, Fink N, et al. The timing of specialist evaluation in chronic kidney disease and mortality. Ann Intern Med. 2002;137(6):479–86.PubMed Kinchen KS, Sadler J, Fink N, et al. The timing of specialist evaluation in chronic kidney disease and mortality. Ann Intern Med. 2002;137(6):479–86.PubMed
20.
Zurück zum Zitat Ifudu O, Dawood M, Iofel Y, Valcourt JS, Friedman EA. Delayed referral of black, Hispanic, and older patients with chronic renal failure. Am J Kidney Dis. 1999;33(4):728–33.CrossRefPubMed Ifudu O, Dawood M, Iofel Y, Valcourt JS, Friedman EA. Delayed referral of black, Hispanic, and older patients with chronic renal failure. Am J Kidney Dis. 1999;33(4):728–33.CrossRefPubMed
21.
Zurück zum Zitat Steel J, Ellis P. Do demographic variables affect the timing of referral to the nephrologist? Edtna-Erca J. 2002;28(4):185–7.PubMed Steel J, Ellis P. Do demographic variables affect the timing of referral to the nephrologist? Edtna-Erca J. 2002;28(4):185–7.PubMed
22.
Zurück zum Zitat Gao SW, Oliver DK, Das N, et al. Assessment of racial disparities in chronic kidney disease stage 3 and 4 care in the department of defense health system. Clin J Am Soc Nephrol. 2008;3(2):442–9.CrossRefPubMed Gao SW, Oliver DK, Das N, et al. Assessment of racial disparities in chronic kidney disease stage 3 and 4 care in the department of defense health system. Clin J Am Soc Nephrol. 2008;3(2):442–9.CrossRefPubMed
23.
Zurück zum Zitat Sisson SD, Rastegar DA, Rice TN, Hughes MT. Multicenter implementation of a shared graduate medical education resource. Arch Intern Med. 2007;167(22):2476–80.CrossRefPubMed Sisson SD, Rastegar DA, Rice TN, Hughes MT. Multicenter implementation of a shared graduate medical education resource. Arch Intern Med. 2007;167(22):2476–80.CrossRefPubMed
24.
Zurück zum Zitat Winkelmayer WC, Glynn RJ, Levin R, Owen WF Jr, Avorn J. Determinants of delayed nephrologist referral in patients with chronic kidney disease. Am J Kidney Dis. 2001;38(6):1178–84.CrossRefPubMed Winkelmayer WC, Glynn RJ, Levin R, Owen WF Jr, Avorn J. Determinants of delayed nephrologist referral in patients with chronic kidney disease. Am J Kidney Dis. 2001;38(6):1178–84.CrossRefPubMed
25.
Zurück zum Zitat Ouseph R, Hendricks P, Hollon JA, Bhimani BD, Lederer ED. Under-recognition of chronic kidney disease in elderly outpatients. Clin Nephrol. 2007;68(6):373–8.PubMed Ouseph R, Hendricks P, Hollon JA, Bhimani BD, Lederer ED. Under-recognition of chronic kidney disease in elderly outpatients. Clin Nephrol. 2007;68(6):373–8.PubMed
26.
Zurück zum Zitat Raymond NT, Zehnder D, Smith SCH, Stinson JA, Lehnert H, Higgins RM. Elevated relative mortality risk with mild-to-moderate chronic kidney disease decreases with age. Nephrol Dial Transplant. 2007;22(11):3214–20.CrossRefPubMed Raymond NT, Zehnder D, Smith SCH, Stinson JA, Lehnert H, Higgins RM. Elevated relative mortality risk with mild-to-moderate chronic kidney disease decreases with age. Nephrol Dial Transplant. 2007;22(11):3214–20.CrossRefPubMed
27.
Zurück zum Zitat O’Hare AM, Choi AI, Bertenthal D, et al. Age affects outcomes in chronic kidney disease. J Am Soc Nephrol. 2007;18(10):2758–65.CrossRefPubMed O’Hare AM, Choi AI, Bertenthal D, et al. Age affects outcomes in chronic kidney disease. J Am Soc Nephrol. 2007;18(10):2758–65.CrossRefPubMed
Metadaten
Titel
Chronic kidney disease management in an academic internal medicine clinic
verfasst von
Benjamin D. Morrow
Ian J. Stewart
Eric W. Barnes
Casey L. Cotant
Publikationsdatum
01.04.2010
Verlag
Springer Japan
Erschienen in
Clinical and Experimental Nephrology / Ausgabe 2/2010
Print ISSN: 1342-1751
Elektronische ISSN: 1437-7799
DOI
https://doi.org/10.1007/s10157-009-0247-6

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