Skip to main content
Erschienen in: AIDS and Behavior 11/2015

01.11.2015 | Original Paper

Informal Caregiver Characteristics Associated with Viral Load Suppression Among Current or Former Injection Drug Users Living with HIV/AIDS

verfasst von: Mary M. Mitchell, Allysha C. Robinson, Trang Q. Nguyen, Amy R. Knowlton

Erschienen in: AIDS and Behavior | Ausgabe 11/2015

Einloggen, um Zugang zu erhalten

Abstract

Few studies have examined the association between having an informal (unpaid) caregiver and viral suppression among persons living with HIV/AIDS (PLHIV) who are on antiretroviral therapy. The current study examined relationships between caregivers’ individual and social network characteristics and care recipient viral suppression. Baseline data were from the BEACON study caregivers and their HIV seropositive former or current drug using care recipients, of whom 89 % were African American (N = 258 dyads). Using adjusted logistic regression, care recipient’s undetectable viral load was positively associated with caregiver’s limited physical functioning and negatively associated with caregivers having few family members to turn to for problem solving, a greater number of current drug users in their network, and poorer perceptions of the care recipient’s mental health. Results further understandings of interpersonal relationship factors important to PLHIV’s health outcomes, and the need for caregiving relationship-focused intervention to promote viral suppression among PLHIV.
Literatur
1.
Zurück zum Zitat Fisher M, Cooper V. HIV and ageing: premature ageing or premature conclusions? Curr Opin Infect Dis. 2012;25(1):1–3. Fisher M, Cooper V. HIV and ageing: premature ageing or premature conclusions? Curr Opin Infect Dis. 2012;25(1):1–3.
2.
Zurück zum Zitat Wolf MS, Davis TC, Osborn CY, et al. Literacy, self-efficacy, and HIV medication adherence. Patient Educ Couns. 2007;65(2):253–60.CrossRefPubMed Wolf MS, Davis TC, Osborn CY, et al. Literacy, self-efficacy, and HIV medication adherence. Patient Educ Couns. 2007;65(2):253–60.CrossRefPubMed
3.
Zurück zum Zitat Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis. 2002;34(8):1115–21.CrossRefPubMed Mannheimer S, Friedland G, Matts J, Child C, Chesney M. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis. 2002;34(8):1115–21.CrossRefPubMed
4.
Zurück zum Zitat Wood E, Hogg RS, Lima VD, et al. Highly active antiretroviral therapy and survival in HIV-infected injection drug users. JAMA. 2008;300:550–4. Wood E, Hogg RS, Lima VD, et al. Highly active antiretroviral therapy and survival in HIV-infected injection drug users. JAMA. 2008;300:550–4.
5.
Zurück zum Zitat Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;573–80. Tucker JS, Burnam MA, Sherbourne CD, Kung FY, Gifford AL. Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. Am J Med. 2003;573–80.
6.
Zurück zum Zitat Kimberlin C, Brushwood D, Allen W, Radson E, Wilson D. Cancer patient and caregiver experiences: communication and pain management issues. J Pain Symptom Manage. 2004;28(6):566–78.CrossRefPubMed Kimberlin C, Brushwood D, Allen W, Radson E, Wilson D. Cancer patient and caregiver experiences: communication and pain management issues. J Pain Symptom Manage. 2004;28(6):566–78.CrossRefPubMed
7.
Zurück zum Zitat Knowlton AR, Curry A, Hua W, Wissow L. Depression and social context: primary supporter relationship factors associated with depressive symptoms among a disadvantaged population with HIV/AIDS. J Community Psychol. 2009;526–41. Knowlton AR, Curry A, Hua W, Wissow L. Depression and social context: primary supporter relationship factors associated with depressive symptoms among a disadvantaged population with HIV/AIDS. J Community Psychol. 2009;526–41.
8.
9.
Zurück zum Zitat Bass DM, Judge KS, Snow AL, et al. Negative caregiving effects among caregivers of veterans with dementia. Am J Geriatr Psychiatry. 2012;20(3):239–47.CrossRefPubMed Bass DM, Judge KS, Snow AL, et al. Negative caregiving effects among caregivers of veterans with dementia. Am J Geriatr Psychiatry. 2012;20(3):239–47.CrossRefPubMed
10.
Zurück zum Zitat Knowlton AR, Latkin CA. Network financial support and conflict as predictors of depressive symptoms among a highly disadvantaged population. J Community Psychol. 2007;35(1):13–28.CrossRef Knowlton AR, Latkin CA. Network financial support and conflict as predictors of depressive symptoms among a highly disadvantaged population. J Community Psychol. 2007;35(1):13–28.CrossRef
11.
Zurück zum Zitat Edwards LV. Perceived social support and HIV/AIDS medication adherence among African American women. Qual Health Res. 2006;16:679–91.CrossRefPubMed Edwards LV. Perceived social support and HIV/AIDS medication adherence among African American women. Qual Health Res. 2006;16:679–91.CrossRefPubMed
12.
Zurück zum Zitat Beals KP, Wight RG, Aneshensel CS, Murphy DA, Miller-Martinez D. The role of family caregivers in HIV medication adherence. AIDS Care. 2006;18(6):589–96.CrossRefPubMed Beals KP, Wight RG, Aneshensel CS, Murphy DA, Miller-Martinez D. The role of family caregivers in HIV medication adherence. AIDS Care. 2006;18(6):589–96.CrossRefPubMed
13.
Zurück zum Zitat Knowlton AR, Arnsten JH, Gourevitch MN, Eldred L, Wilkinson JD, Rose CD, Buchanan A, Purcell DW. Microsocial environmental influences on highly active antiretroviral therapy outcomes among active injection drug users. J Acquir Immune Defic Syndr. 2007;46(2):S110–9.CrossRefPubMed Knowlton AR, Arnsten JH, Gourevitch MN, Eldred L, Wilkinson JD, Rose CD, Buchanan A, Purcell DW. Microsocial environmental influences on highly active antiretroviral therapy outcomes among active injection drug users. J Acquir Immune Defic Syndr. 2007;46(2):S110–9.CrossRefPubMed
14.
Zurück zum Zitat Knowlton AR, Yang C, Bohnert A, et al. Informal care and reciprocity of support are associated with HAART adherence among men in Baltimore, MD, USA. AIDS Behav. 2011;15:1429–36.PubMedCentralCrossRefPubMed Knowlton AR, Yang C, Bohnert A, et al. Informal care and reciprocity of support are associated with HAART adherence among men in Baltimore, MD, USA. AIDS Behav. 2011;15:1429–36.PubMedCentralCrossRefPubMed
15.
Zurück zum Zitat Bachner YG, Carmel S. Open communication between caregivers and terminally ill cancer patients: the role of caregivers’ characteristics and situational variables. Health Commun. 2009;24(6):524–31.CrossRefPubMed Bachner YG, Carmel S. Open communication between caregivers and terminally ill cancer patients: the role of caregivers’ characteristics and situational variables. Health Commun. 2009;24(6):524–31.CrossRefPubMed
16.
Zurück zum Zitat Wittenberg-Lyles E, Demiris G, Oliver DP, Burt S. Reciprocal suffering: caregiver concerns during hospice care. J Pain Symp Manage. 2011;41(2):383–93.CrossRef Wittenberg-Lyles E, Demiris G, Oliver DP, Burt S. Reciprocal suffering: caregiver concerns during hospice care. J Pain Symp Manage. 2011;41(2):383–93.CrossRef
18.
Zurück zum Zitat Arribas JR, Horban A, Gerstoft J, et al. The MONET trial: darunavir/ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml. AIDS. 2010;(2):223–30. Arribas JR, Horban A, Gerstoft J, et al. The MONET trial: darunavir/ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml. AIDS. 2010;(2):223–30.
19.
Zurück zum Zitat Lawton MP, Brody EM. Assessment of older people: Self-maintaining and instrumental activities of daily living activities of daily living. Gerontologist. 1969;9:179–86. Lawton MP, Brody EM. Assessment of older people: Self-maintaining and instrumental activities of daily living activities of daily living. Gerontologist. 1969;9:179–86.
20.
Zurück zum Zitat Radloff LS. CES-D scale: a self-report depression scale for research in the general populations. Appl Psych Meas. 1977;1:385–401.CrossRef Radloff LS. CES-D scale: a self-report depression scale for research in the general populations. Appl Psych Meas. 1977;1:385–401.CrossRef
21.
Zurück zum Zitat IBM Corporation. IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corporation; 1999. IBM Corporation. IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corporation; 1999.
22.
Zurück zum Zitat Stetz KM, Brown MA. Physical and psychosocial health in family caregiving: a comparison of AIDS and cancer caregivers. Public Health Nurs. 2004;21:533–40.CrossRefPubMed Stetz KM, Brown MA. Physical and psychosocial health in family caregiving: a comparison of AIDS and cancer caregivers. Public Health Nurs. 2004;21:533–40.CrossRefPubMed
23.
Zurück zum Zitat Dyer TP, Stein JA, Rice E, Rotheram-Borus MJ. Predicting depression in mothers with and without HIV: the role of social support and family dynamics. AIDS Behav. 2012;16(8):2198–208.PubMedCentralCrossRefPubMed Dyer TP, Stein JA, Rice E, Rotheram-Borus MJ. Predicting depression in mothers with and without HIV: the role of social support and family dynamics. AIDS Behav. 2012;16(8):2198–208.PubMedCentralCrossRefPubMed
24.
Zurück zum Zitat Mosack KE, Petroll A. Patients’ perspectives on informal caregiver involvement in HIV health care appointments. AIDS Patient Care STDS. 2009;23(12):1043–51.PubMedCentralCrossRefPubMed Mosack KE, Petroll A. Patients’ perspectives on informal caregiver involvement in HIV health care appointments. AIDS Patient Care STDS. 2009;23(12):1043–51.PubMedCentralCrossRefPubMed
25.
Zurück zum Zitat Mitchell MM, Robinson AC, Wolff JL, Knowlton AR. Perceived mental health status of injection drug users living with HIV/AIDS: concordance between informal HIV caregivers and care recipient self-reports and associations with caregiving burden and reciprocity. AIDS Behav. 2014;18(1):1103–13.PubMedCentralCrossRefPubMed Mitchell MM, Robinson AC, Wolff JL, Knowlton AR. Perceived mental health status of injection drug users living with HIV/AIDS: concordance between informal HIV caregivers and care recipient self-reports and associations with caregiving burden and reciprocity. AIDS Behav. 2014;18(1):1103–13.PubMedCentralCrossRefPubMed
26.
Zurück zum Zitat Carrico AW, Bangsberg DR, Weiser SD, et al. Psychiatric correlates of HAART utilization and viral load among HIV-positive impoverished persons. AIDS. 2011;25(8):1113–8.PubMedCentralCrossRefPubMed Carrico AW, Bangsberg DR, Weiser SD, et al. Psychiatric correlates of HAART utilization and viral load among HIV-positive impoverished persons. AIDS. 2011;25(8):1113–8.PubMedCentralCrossRefPubMed
27.
Zurück zum Zitat Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acq Immu Def Synd. 2011;58(2):181–7. Gonzalez JS, Batchelder AW, Psaros C, Safren SA. Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis. J Acq Immu Def Synd. 2011;58(2):181–7.
28.
Zurück zum Zitat Mehta S, Moore RD, Graham NM. Potential factors affecting adherence with HIV therapy. AIDS. 1997;11(14):1665–70. Mehta S, Moore RD, Graham NM. Potential factors affecting adherence with HIV therapy. AIDS. 1997;11(14):1665–70.
29.
Zurück zum Zitat Kaaya S, Eustache E, Lapidos-Salaiz I, et al. Grand challenges: improving HIV treatment outcomes by integrating interventions for co-morbid mental illness. PLoS Med. 2013;10(5):e1001447.PubMedCentralCrossRefPubMed Kaaya S, Eustache E, Lapidos-Salaiz I, et al. Grand challenges: improving HIV treatment outcomes by integrating interventions for co-morbid mental illness. PLoS Med. 2013;10(5):e1001447.PubMedCentralCrossRefPubMed
30.
Zurück zum Zitat Reich WA, Lounsbury DW, Zaid-Muhammad S, Rapkin BD. Forms of social support and their relationships to mental health in HIV-positive persons. Psychol Health Med. 2010;15(2):135–45.CrossRefPubMed Reich WA, Lounsbury DW, Zaid-Muhammad S, Rapkin BD. Forms of social support and their relationships to mental health in HIV-positive persons. Psychol Health Med. 2010;15(2):135–45.CrossRefPubMed
31.
Zurück zum Zitat Pearlin LI, Mullan JT, Semple SJ, Skaff MM. Caregiving and the stress process: an overview of concepts and their measures. Gerontologist. 1990;30(5):583–94.CrossRefPubMed Pearlin LI, Mullan JT, Semple SJ, Skaff MM. Caregiving and the stress process: an overview of concepts and their measures. Gerontologist. 1990;30(5):583–94.CrossRefPubMed
32.
Zurück zum Zitat Gross R, Bellamy SL, Chapman J, et al. Managed problem solving for antiretroviral therapy adherence. JAMA Intern Med. 2013;173(4):300–6. Gross R, Bellamy SL, Chapman J, et al. Managed problem solving for antiretroviral therapy adherence. JAMA Intern Med. 2013;173(4):300–6.
Metadaten
Titel
Informal Caregiver Characteristics Associated with Viral Load Suppression Among Current or Former Injection Drug Users Living with HIV/AIDS
verfasst von
Mary M. Mitchell
Allysha C. Robinson
Trang Q. Nguyen
Amy R. Knowlton
Publikationsdatum
01.11.2015
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 11/2015
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-015-1090-2

Weitere Artikel der Ausgabe 11/2015

AIDS and Behavior 11/2015 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.