Erschienen in:
01.02.2006 | Editorial
A Weight Loss Trial for Breast Cancer Recurrence: Pre-Menopausal, Post-Menopausal, Both, or Neither?
verfasst von:
Tim Byers, Rebecca L. Sedjo
Erschienen in:
Cancer Causes & Control
|
Ausgabe 1/2006
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Excerpt
Because the link between adiposity (overweight and obesity) and breast cancer outcomes has been apparent for many years, it seems that a randomized controlled trial to test the effects of weight loss on breast cancer recurrence is long overdue. In this commentary we will review the rationale for such a trial and comment on how emerging changes in clinical practice and surprising observations from recent research would suggest that if we had already begun such a trial we might well have designed it incorrectly. Perhaps, then, it is fortunate that such a large-scale trial has not yet been initiated. Our bottom line: whether such a trial should now be done among pre-menopausal breast cancer survivors, among post-menopausal survivors, among both, or perhaps among neither, is not clear. …