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International Ophthalmology
Erschienen in: International Ophthalmology 4/2017

28.09.2016 | Original Paper

Optic nerve head slope-based quantitative parameters for identifying open-angle glaucoma on SPECTRALIS OCT images

verfasst von: Abdel-Razzak M. Al-Hinnawi, Bassam O. Al-Naami, Motasem M. Al-Latayfeh

Erschienen in: International Ophthalmology | Ausgabe 4/2017

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Abstract

Purpose

To investigate monitoring slope-based features of the optic nerve head (ONH) cup as open-angle glaucoma (OAG) occurs.

Method

A dataset of 46 retrospective OCT cases was acquired from the SPECTRALIS Heidelberg Engineering OCT device. A set of five parameters, which are based on the ONH cup-incline, are measured on the OAG and normal subjects in the dataset. Then, three new ONH cup-shape indices were deduced. The ONH cup-incline parameters and ONH cup-shape indices are analyzed to estimate their clinical value.

Results

The statistical difference between measurements on normal and glaucoma eyes was remarkably significant for all of the analyzed parameters and indices (p value < 0.001).

Conclusions

The geometric shape of the ONH cup can be transferred to numerical parameters and indices. The proposed ONH cup-incline parameters and ONH cup-shape indices have shown suggestive clinical value to identify the development of OAG. As OAG appears, the top ONH cup-incline parameters decrease while the bottom ONH cup-incline parameters increase. The ONH cup-shape indices suggest capability to discriminate OAG from normal eyes.
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Metadaten
Titel
Optic nerve head slope-based quantitative parameters for identifying open-angle glaucoma on SPECTRALIS OCT images
verfasst von
Abdel-Razzak M. Al-Hinnawi
Bassam O. Al-Naami
Motasem M. Al-Latayfeh
Publikationsdatum
28.09.2016
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 4/2017
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-016-0362-9

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