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Erschienen in: Journal of Neuro-Oncology 2/2008

01.09.2008 | Clinical-Patient Study

Radio-induced gliomas: 20-year experience and critical review of the pathology

verfasst von: Maurizio Salvati, Alessandro D’Elia, Graziella Angelina Melone, Christian Brogna, Alessandro Frati, Antonino Raco, Roberto Delfini

Erschienen in: Journal of Neuro-Oncology | Ausgabe 2/2008

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Abstract

The authors report their personal experience with a surgical series of 16 cases of cerebral radiation-induced gliomas, defining diagnostic criteria and surgical and clinical characteristics. There were ten males and six females, with a median age of 45.9 years. Irradiation had initially been given for acute lymphoblastic leukemia (ALL) in six cases, tinea capitis in four cases, scalp hemangioma in three cases, cutaneous hemangioma, cavernous angioma, and medulloblastoma in one case each. There were 14 cases of glioblastoma (grade IV WHO) and 2 cases of astrocytoma (grade II WHO), with a mean latency time of 17 years (range: 6–26 years). For glioblastomas mean survival time was 10.4 months, accounting for 1–3% of all the glioblastomas treated. A thorough revision of the pertinent literature revealed some clinical–biological peculiarities.
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Metadaten
Titel
Radio-induced gliomas: 20-year experience and critical review of the pathology
verfasst von
Maurizio Salvati
Alessandro D’Elia
Graziella Angelina Melone
Christian Brogna
Alessandro Frati
Antonino Raco
Roberto Delfini
Publikationsdatum
01.09.2008
Verlag
Springer US
Erschienen in
Journal of Neuro-Oncology / Ausgabe 2/2008
Print ISSN: 0167-594X
Elektronische ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-008-9565-x

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