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Erschienen in: Pituitary 1/2009

01.03.2009

Radiotherapy of nonfunctioning and gonadotroph adenomas

verfasst von: Andrew A. Kanner, Benjamin W. Corn, Yona Greenman

Erschienen in: Pituitary | Ausgabe 1/2009

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Abstract

Transsphenoidal surgery is the treatment of choice for NFPA but is seldom curative. The management of patients in whom residual tumor is detected after surgery is not clear-cut. Radiation therapy is effective in controlling tumor mass in the majority of patients, but is associated with long term complications that call for restriction of its use to patients at high risk for tumor growth. New radiation techniques may prove to be safer while retaining the effectiveness of conventional radiotherapy, however longer follow-up is necessary to confirm this assumption. For now, it appears to be safe to withhold radiation and carefully follow patients with small tumor remnants, whereas large remnants from invasive tumors should be considered for radiotherapy. Nevertheless, there are no prospective controlled studies that support this empirical approach.
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Metadaten
Titel
Radiotherapy of nonfunctioning and gonadotroph adenomas
verfasst von
Andrew A. Kanner
Benjamin W. Corn
Yona Greenman
Publikationsdatum
01.03.2009
Verlag
Springer US
Erschienen in
Pituitary / Ausgabe 1/2009
Print ISSN: 1386-341X
Elektronische ISSN: 1573-7403
DOI
https://doi.org/10.1007/s11102-008-0089-3

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