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01.07.2015 | Letter to the Editor

Diphenidine and its metabolites in blood and urine analyzed by MALDI-Q-TOF mass spectrometry

verfasst von: Kayoko Minakata, Itaru Yamagishi, Hideki Nozawa, Koutaro Hasegawa, Amin Wurita, Kunio Gonmori, Masako Suzuki, Kanako Watanabe, Osamu Suzuki

Erschienen in: Forensic Toxicology | Ausgabe 2/2015

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Dear Editor …

Uchiyama N, Shimokawa Y, Kawamura M, Kikura-Hanajiri R, Hakamatsuka T (2014) Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products. Forensic Toxicol 32:266–281CrossRef

Wurita A, Hasegawa K, Minakata K, Watanabe K, Suzuki O (2014) A large amount of new designer drug diphenidine coexisting with a synthetic cannabinoid 5-fluoro-AB-PINACA found in a dubious herbal product. Forensic Toxicol 32:331–337CrossRef

Hasegawa K, Wurita A, Minakata K, Gonmori K, Nozawa H, Yamagishi I, Watanabe K, Suzuki O (2015) Postmortem distribution of AB-CHMINACA, 5-fluoro-AMB, and diphenidine in body fluids and solid tissues in a fatal poisoning case: usefulness of the adipose tissue for detection of drugs in unchanged forms. Forensic Toxicol 33:45–53CrossRef

Berger ML, Schweifer A, Rebernik P, Hammerschmidt F (2009) NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenyl-ethyl) piperidine enantiomers and of related compounds. Bioorg Med Chem 17:3456–3462PubMedCrossRef

PsychonautWiki (2014) Diphenidine. http://psychonautwiki.org/wiki/Diphenidine. Accessed Dec 2014

Minakata K, Yamagishi I, Nozawa H, Hasegawa K, Wurita A, Gonmori K, Suzuki M, Watanabe K, Suzuki O (2015) Determination of new pyrrolidino cathinone derivatives, PVT, F-PVP, MPHP, PV8, PV9, and F-PV9, in human blood by MALDI-Q-TOF mass spectrometry. Forensic Toxicol 33:148–154CrossRef

Springer D, Fritschi G, Maurer HH (2003) Metabolism of the new designer drug α-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyl-α-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography–mass spectrometry. J Chromatogr B 796:253–266CrossRef

Shima N, Katagi M, Kamata H, Matsuta S, Sasaki K, Kamata T, Nishioka H, Miki A, Tatsuno M, Zaitsu K, Ishii A, Sato T, Tsuchihashi H, Suzuki K (2014) Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites. Forensic Toxicol 32:59–67CrossRef

Namera A, Konuma K, Kawamura M, Saito T, Nakamoto A, Yahata M, Ohta S, Miyazaki S, Shiraishi H, Nagao M (2014) Time-course profile of urinary excretion of intravenously administered α-pyrrolidinovalerophenone and α-pyrrolidinobutiophenone in human. Forensic Toxicol 32:68–74CrossRef

Titel: Diphenidine and its metabolites in blood and urine analyzed by MALDI-Q-TOF mass spectrometry
verfasst von: Kayoko Minakata
Itaru Yamagishi
Hideki Nozawa
Koutaro Hasegawa
Amin Wurita
Kunio Gonmori
Masako Suzuki
Kanako Watanabe
Osamu Suzuki
Publikationsdatum: 01.07.2015
Verlag: Springer Japan
Erschienen in: Forensic Toxicology / Ausgabe 2/2015
Print ISSN: 1860-8965
Elektronische ISSN: 1860-8973
DOI: https://doi.org/10.1007/s11419-015-0273-x

Springer Medizin

Diphenidine and its metabolites in blood and urine analyzed by MALDI-Q-TOF mass spectrometry

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Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

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