nach oben

Erschienen in:

01.04.2014 | Abdominal Radiology

Imaging findings of hepatic focal nodular hyperplasia in men and women: are they really different?

verfasst von: Tommaso Vincenzo Bartolotta, Adele Taibbi, Giuseppe Brancatelli, Domenica Matranga, Marisa Tumbarello, Massimo Midiri, Roberto Lagalla

Erschienen in: La radiologia medica | Ausgabe 4/2014

Einloggen, um Zugang zu erhalten

Abstract

Purpose

This study was undertaken to compare the imaging findings of focal nodular hyperplasia (FNH) in men and women, as seen on multidetector computed tomography (MDCT), magnetic resonance imaging (MRI) and contrast-enhanced ultrasound (CEUS).

Materials and methods

Two radiologists reviewed 195 imaging studies (17 MDCT, 81 MRI and 97 CEUS examinations) pertaining to 111 FNHs (mean size 3 cm) in 91 patients (mean age 39 years). For each lesion, the readers assessed size, location, echogenicity, attenuation, or signal intensity in comparison with adjacent liver parenchyma on both unenhanced and postcontrast images.

Results

Eighty-nine FNHs (mean size 3.1 cm) were observed in 73 women (mean age 37.9 years) and 22 FNHs (mean size 2.7 cm) in 18 men (mean age 41.2 years). No statistically significant differences were found between men and women in terms of age, FNH lesions per patient (1.22 and 1.21, respectively), size, baseline and enhancement pattern on MRI, CEUS and MDCT (p < 0.05). A central scar in FNHs was depicted in 4/18 (22.2 %) men and 16/63 (25.4 %) women on MRI (p < 0.05), and in 1/2 (50 %) men and 7/15 (46.7 %) women on MDCT (p < 0.05), whereas a spoke-wheel pattern, central scar, and/or feeding vessel were seen in 5/17 (29.4 %) men and 22/80 (27.5 %) women on CEUS (p < 0.05).

Conclusions

Our results did not show any differences in imaging features, age of occurrence and size of FNH between men and women.

Vilgrain V (2006) Focal nodular hyperplasia. Eur J Radiol 58:236–245PubMedCrossRef

Ros PR, Menu Y, Vilgrain V et al (2001) Liver neoplasms and tumor-like conditions. Eur Radiol 11(Suppl 2):S145–S165

Luciani A, Kobeiter H, Maison P et al (2002) Focal nodular hyperplasia of the liver in men: is presentation the same in men and women? Gut 50:877–880PubMedCentralPubMedCrossRef

Nguyen BN, Fléjou JF, Terris B et al (1999) Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol 23:1441–1454PubMedCrossRef

Bartolotta TV, Taibbi A, Matranga D et al (2010) Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity. Eur Radiol 20:2248–2256PubMedCrossRef

Hussain SH, Terkivatan T, Zondervan PE et al (2004) Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis. Radiographics 24:3–19PubMedCrossRef

Brancatelli G, Federle MP, Grazioli L et al (2001) Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. Radiology 219:61–68PubMedCrossRef

World Medical Association (2000) Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 284:3043–3045CrossRef

Bartolotta TV, Taibbi A, Midiri M et al (2009) Focal liver lesions: contrast-enhanced ultrasound. Abdom Imaging 34:193–209PubMedCrossRef

10.

Kim TK, Jang HJ, Burns PN et al (2008) Focal nodular hyperplasia and hepatic adenoma: differentiation with low-mechanical-index contrast-enhanced sonography. AJR Am J Roentgenol 190:58–66PubMedCrossRef

11.

Ungermann L, Eliás P, Zizka J et al (2007) Focal nodular hyperplasia: spoke-wheel arterial pattern and other signs on dynamic contrast-enhanced ultrasonography. Eur J Radiol 63:290–294PubMedCrossRef

12.

Grazioli L, Morana G, Kirchin MA et al (2005) Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study. Radiology 236:166–177PubMedCrossRef

13.

Grazioli L, Bondioni MP, Haradome H et al (2012) Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis. Radiology 262:520–529PubMedCrossRef

14.

Purysko AS, Remer EM, Coppa CP et al (2012) Characteristics and distinguishing features of hepatocellular adenoma and focal nodular hyperplasia on gadoxetate disodium-enhanced MRI. AJR Am J Roentgenol 198:115–123PubMedCrossRef

15.

Zech CJ, Grazioli L, Breuer J et al (2008) Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: results of a multicenter trial. Invest Radiol 43:504–511PubMedCrossRef

Titel: Imaging findings of hepatic focal nodular hyperplasia in men and women: are they really different?
verfasst von: Tommaso Vincenzo Bartolotta
Adele Taibbi
Giuseppe Brancatelli
Domenica Matranga
Marisa Tumbarello
Massimo Midiri
Roberto Lagalla
Publikationsdatum: 01.04.2014
Verlag: Springer Milan
Erschienen in: La radiologia medica / Ausgabe 4/2014
Print ISSN: 0033-8362
Elektronische ISSN: 1826-6983
DOI: https://doi.org/10.1007/s11547-013-0333-4

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Imaging findings of hepatic focal nodular hyperplasia in men and women: are they really different?