Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Typ-2-Diabetes und Adipositas Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende

Die Highlights vom Kongress des American College of Cardiology 2024

Im April diskutierten die Herz-Kreislauf-Spezialisten aus der ganzen Welt auf dem  Kongress des American College of Cardiology (ACC) u.a. neue Therapieansätze bei akutem Myokardinfarkt, koronarer Herzerkrankung, kardiogenem Schock oder Aortenklappenstenose. In unserem Kongress-Dossier haben wir für Sie Berichte über die „Late-Breaking Trials“ und andere wichtige Studien zusammengestellt. 
Erweiterte Suche
Anmelden
nach oben
Current Cardiology Reports
Erschienen in: Current Cardiology Reports 2/2015

01.02.2015 | Echocardiography (JM Gardin, Section Editor)

Echocardiographic Evaluation of Left Ventricular Diastolic Function: an Update

verfasst von: Dimitrios Maragiannis, Sherif F. Nagueh

Erschienen in: Current Cardiology Reports | Ausgabe 2/2015

Einloggen, um Zugang zu erhalten

Abstract

Echocardiographic evaluation of diastolic properties and assessment of hemodynamic status of the right and the left ventricle have been traditionally applied for many years in clinical practice. Establishment of diagnosis of diastolic dysfunction, grading, and estimation of filling pressures noninvasively adds prognostic information to the clinician, which may affect treatment management. Novel methods, including left atrium strain, left ventricular diastolic strain rate, and left ventricular untwisting rate, have been imported in clinical practice attempting to provide a more comprehensive and more accurate understanding of the mechanisms and diagnosis of diastolic dysfunction.
Literatur
1.
Nagueh SF, Appleton CP, Gillebert TC, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr. 2009;22:107–33.CrossRefPubMed
2.
Redfield MM, Jacobsen SJ, Burnett JC, et al. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003;289:194–202.CrossRefPubMed
3.
4.•
Aljaroudi W, Alraies MC, Halley C, et al. Impact of progression of diastolic dysfunction on mortality in patients with normal ejection fraction. Circulation. 2012;125:782–8. Important study showing the adverse effects of progression of diastolic dysfunction with an increase in total mortality.CrossRefPubMed
5.•
Kuznetsova T, Thijs L, Knez J, et al. Prognostic value of left ventricular diastolic dysfunction in a general population. J Am Heart Assoc. 2014;3:e000789. An interesting study showing the prognostic power of a simple diastolic measurement in a general population.CrossRefPubMedCentralPubMed
6.
Oki T, Tabata T, Yamada H, et al. Clinical application of pulsed Doppler tissue imaging for assessing abnormal left ventricular relaxation. Am J Cardiol. 1997;79:921–8.CrossRefPubMed
7.
Hillis GS, Moller JE, Pellikka PA, et al. Noninvasive estimation of left ventricular filling pressure by E/e’ is a powerful predictor of survival after acute myocardial infarction. J Am Coll Cardiol. 2004;43:360–7.CrossRefPubMed
8.
Wang M, Yip GW, Wang AY, et al. Tissue Doppler imaging provides incremental prognostic value in patients with systemic hypertension and left ventricular hypertrophy. J Hypertens. 2005;23:183–91.CrossRefPubMed
9.
Bruch C, Klem I, Breithardt G, et al. Diagnostic usefulness and prognostic implications of the mitral E/E’ ratio in patients with heart failure and severe secondary mitral regurgitation. Am J Cardiol. 2007;100:860–5.CrossRefPubMed
10.
Wang M, Yip G, Yu CM, et al. Independent and incremental prognostic value of early mitral annulus velocity in patients with impaired left ventricular systolic function. J Am Coll Cardiol. 2005;45:272–7.CrossRefPubMed
11.
Sharma R, Pellerin D, Gaze DC, et al. Mitral peak Doppler E-wave to peak mitral annulus velocity ratio is an accurate estimate of left ventricular filling pressure and predicts mortality in end-stage renal disease. J Am Soc Echocardiogr. 2006;19:266–73.CrossRefPubMed
12.
Okura H, Takada Y, Kubo T, et al. Tissue Doppler-derived index of left ventricular filling pressure, E/E’, predicts survival of patients with non-valvular atrial fibrillation. Heart. 2006;92:1248–52.CrossRefPubMedCentralPubMed
13.
McMahon CJ, Nagueh SF, Eapen RS, et al. Echocardiographic predictors of adverse clinical events in children with dilated cardiomyopathy: a prospective clinical study. Heart. 2004;90:908–15.CrossRefPubMedCentralPubMed
14.
McMahon CJ, Nagueh SF, Pignatelli RH, et al. Characterization of left ventricular diastolic function by tissue Doppler imaging and clinical status in children with hypertrophic cardiomyopathy. Circulation. 2004;109:1756–62.CrossRefPubMed
15.
Chang SA, Park PW, Sung K, et al. Noninvasive estimate of left ventricular filling pressure correlated with early and midterm postoperative cardiovascular events after isolated aortic valve replacement in patients with severe aortic stenosis. J Thorac Cardiovasc Surg. 2010;140:1361–6.CrossRefPubMed
16.
Nagueh SF, Middleton KJ, Kopelen HA, et al. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol. 1997;30:1527–33.CrossRefPubMed
17.
Sohn DW, Song JM, Zo JH, et al. Mitral annulus velocity in the evaluation of left ventricular diastolic function in atrial fibrillation. J Am Soc Echocardiogr. 1999;12:927–31.CrossRefPubMed
18.
Nagueh SF, Mikati I, Kopelen HA, et al. Doppler estimation of left ventricular filling pressure in sinus tachycardia. A new application of tissue Doppler imaging. Circulation. 1998;98:1644–50.CrossRefPubMed
19.
Sohn DW, Kim YJ, Kim HC, et al. Evaluation of left ventricular diastolic function when mitral E and A waves are completely fused: role of assessing mitral annulus velocity. J Am Soc Echocardiogr. 1999;12:203–8.CrossRefPubMed
20.
Ommen SR, Nishimura RA, Appleton CP, et al. Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: a comparative simultaneous Doppler-catheterization study. Circulation. 2000;102:1788–94.CrossRefPubMed
21.
Kim YJ, Sohn DW. Mitral annulus velocity in the estimation of left ventricular filling pressure: prospective study in 200 patients. J Am Soc Echocardiogr. 2000;13:980–5.CrossRefPubMed
22.
Kasner M, Westermann D, Steendijk P, et al. Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study. Circulation. 2007;116:637–47.CrossRefPubMed
23.
Rivas-Gotz C, Manolios M, Thohan V, et al. Impact of left ventricular ejection fraction on estimation of left ventricular filling pressures using tissue Doppler and flow propagation velocity. Am J Cardiol. 2003;91:780–4.CrossRefPubMed
24.
Mullens W, Borowski AG, Curtin RJ, et al. Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure. Circulation. 2009;119:62–70.CrossRefPubMedCentralPubMed
25.
Nagueh SF, Bhatt R, Vivo RP, et al. Echocardiographic evaluation of hemodynamics in patients with decompensated systolic heart failure. Circ Cardiovasc Imaging. 2011;4:220–7.CrossRefPubMed
26.
Ritzema JL, Richards AM, Crozier IJ, et al. Serial Doppler echocardiography and tissue Doppler imaging in the detection of elevated directly measured left atrial pressure in ambulant subjects with chronic heart failure. JACC Cardiovasc Imaging. 2011;4:927–34.CrossRefPubMed
27.
Rafique AM, Phan A, Tehrani F, et al. Transthoracic echocardiographic parameters in the estimation of pulmonary capillary wedge pressure in patients with present or previous heart failure. Am J Cardiol. 2012;110:689–94.CrossRefPubMed
28.
Rivas-Gotz C, Khoury DS, Manolios M, et al. Time interval between onset of mitral inflow and onset of early diastolic velocity by tissue Doppler: a novel index of left ventricular relaxation: experimental studies and clinical application. J Am Coll Cardiol. 2003;42:1463–70.CrossRefPubMed
29.
Diwan A, McCulloch M, Lawrie GM, et al. Doppler estimation of left ventricular filling pressures in patients with mitral valve disease. Circulation. 2005;111:3281–9.CrossRefPubMed
30.
Nagueh SF, Kopelen HA, Quinones MA. Assessment of left ventricular filling pressures by Doppler in the presence of atrial fibrillation. Circulation. 1996;94:2138–45.CrossRefPubMed
31.
Chirillo F, Brunazzi MC, Barbiero M, et al. Estimating mean pulmonary wedge pressure in patients with chronic atrial fibrillation from transthoracic Doppler indexes of mitral and pulmonary venous flow velocity. J Am Coll Cardiol. 1997;30:19–26.CrossRefPubMed
32.
Wada Y, Murata K, Tanaka T, et al. Simultaneous Doppler tracing of transmitral inflow and mitral annular velocity as an estimate of elevated left ventricular filling pressure in patients with atrial fibrillation. Circ J. 2012;76:675–81.CrossRefPubMed
33.
Kusunose K, Yamada H, Nishio S, et al. Clinical utility of single-beat E/e’ obtained by simultaneous recording of flow and tissue Doppler velocities in atrial fibrillation with preserved systolic function. JACC Cardiovasc Imaging. 2009;2:1147–56.CrossRefPubMed
34.
Ha JW, Choi D, Park S, et al. Left ventricular diastolic functional reserve during exercise in patients with impaired myocardial relaxation at rest. Heart. 2009;95:399–404.CrossRefPubMed
35.
Talreja DR, Nishimura RA, Oh JK. Estimation of left ventricular filling pressure with exercise by Doppler echocardiography in patients with normal systolic function: a simultaneous echocardiographic-cardiac catheterization study. J Am Soc Echocardiogr. 2007;20:477–9.CrossRefPubMed
36.
Burgess MI, Jenkins C, Sharman JE, et al. Diastolic stress echocardiography: hemodynamic validation and clinical significance of estimation of ventricular filling pressure with exercise. J Am Coll Cardiol. 2006;47:1891–900.CrossRefPubMed
37.
Holland DJ, Prasad SB, Marwick TH. Prognostic implications of left ventricular filling pressure with exercise. Circ Cardiovasc Imaging. 2010;3:149–56.CrossRefPubMed
38.
Duncan AM, Lim E, Gibson DC, et al. Effect of dobutamine stress on left ventricular filling in ischemic dilated cardiomyopathy: pathophysiology and prognostic implications. J Am Coll Cardiol. 2005;46:488–96.CrossRefPubMed
39.
Kato T, Noda A, Izawa H, et al. Myocardial velocity gradient as a noninvasively determined index of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 2003;42:278–85.CrossRefPubMed
40.
Wang J, Khoury DS, Thohan V, et al. Global diastolic strain rate for the assessment of left ventricular relaxation and filling pressures. Circulation. 2007;115:1376–83.CrossRefPubMed
41.
Wakami K, Ohte N, Sakata S, et al. Myocardial radial strain in early diastole is useful for assessing left ventricular early diastolic function: comparison with invasive parameters. J Am Soc Echocardiogr. 2008;21:446–51.CrossRefPubMed
42.
Abraham TP, Belohlavek M, Thomson HL, et al. Time to onset of regional relaxation: feasibility, variability and utility of a novel index of regional myocardial function by strain rate imaging. J Am Coll Cardiol. 2002;39:1531–7.CrossRefPubMed
43.
Park SM, Miyazaki C, Prasad A, et al. Feasibility of prediction of myocardial viability with Doppler tissue imaging following percutaneous coronary intervention for ST elevation anterior myocardial infarction. J Am Soc Echocardiogr. 2009;22:183–9.CrossRefPubMed
44.
Hoffmann R, Altiok E, Nowak B, et al. Strain rate analysis allows detection of differences in diastolic function between viable and nonviable myocardial segments. J Am Soc Echocardiogr. 2005;18:330–5.CrossRefPubMed
45.
Ishii K, Suyama T, Imai M, et al. Abnormal regional left ventricular systolic and diastolic function in patients with coronary artery disease undergoing percutaneous coronary intervention: clinical significance of post-ischemic diastolic stunning. J Am Coll Cardiol. 2009;54:1589–97.CrossRefPubMed
46.
Shanks M, Ng AC, van de Veire NR, et al. Incremental prognostic value of novel left ventricular diastolic indexes for prediction of clinical outcome in patients with ST-elevation myocardial infarction. Am J Cardiol. 2010;105:592–7.CrossRefPubMed
47.
Kimura K, Takenaka K, Ebihara A, et al. Speckle tracking global strain rate E/E’ predicts LV filling pressure more accurately than traditional tissue Doppler E/E’. Echocardiography. 2012;29:404–10.CrossRefPubMed
48.
Kasner M, Gaub R, Sinning D, et al. Global strain rate imaging for the estimation of diastolic function in HFNEF compared with pressure-volume loop analysis. Eur J Echocardiogr. 2010;11:743–51.CrossRefPubMed
49.
Dokainish H, Sengupta R, Pillai M, et al. Usefulness of new diastolic strain and strain rate indexes for the estimation of left ventricular filling pressure. Am J Cardiol. 2008;101:1504–9.CrossRefPubMed
50.
Meluzin J, Spinarova L, Hude P, et al. Estimation of left ventricular filling pressures by speckle tracking echocardiography in patients with idiopathic dilated cardiomyopathy. Eur J Echocardiogr. 2011;12:11–8.CrossRefPubMed
51.•
Hsu PC, Lee WH, Chu CY, et al. The ratio of early mitral inflow velocity to global diastolic strain rate as a useful predictor of cardiac outcomes in patients with atrial fibrillation. J Am Soc Echocardiogr. 2014;27:717–25. Interesting study showing the prognostic power of diastolic strain rate measurements in patients with atrial fibrillation.CrossRefPubMed
52.•
Ersboll M, Andersen MJ, Valeur N, et al. Early diastolic strain rate in relation to systolic and diastolic function and prognosis in acute myocardial infarction: a two-dimensional speckle-tracking study. Eur Heart J. 2014;35:648–56. Interesting study showing the prognostic power of diastolic strain rate measurements in patients with acute myocardial infarction.CrossRefPubMed
53.
Sengupta PP, Tajik AJ, Chandrasekaran K, et al. Twist mechanics of the left ventricle: principles and application. JACC Cardiovasc Imaging. 2008;1:366–76.CrossRefPubMed
54.
Notomi Y, Setser RM, Shiota T, et al. Assessment of left ventricular torsional deformation by Doppler tissue imaging: validation study with tagged magnetic resonance imaging. Circulation. 2005;111:1141–7.CrossRefPubMed
55.
Notomi Y, Lysyansky P, Setser RM, et al. Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging. J Am Coll Cardiol. 2005;45:2034–41.CrossRefPubMed
56.
Pacileo G, Baldini L, Limongelli G, et al. Prolonged left ventricular twist in cardiomyopathies: a potential link between systolic and diastolic dysfunction. Eur J Echocardiogr. 2011;12:841–9.CrossRefPubMed
57.
Takeuchi M, Borden WB, Nakai H, et al. Reduced and delayed untwisting of the left ventricle in patients with hypertension and left ventricular hypertrophy: a study using two-dimensional speckle tracking imaging. Eur Heart J. 2007;28:2756–62.CrossRefPubMed
58.
Notomi Y, Martin-Miklovic MG, Oryszak SJ, et al. Enhanced ventricular untwisting during exercise: a mechanistic manifestation of elastic recoil described by Doppler tissue imaging. Circulation. 2006;113:2524–33.CrossRefPubMed
59.
Dong SJ, Hees PS, Siu CO, et al. MRI assessment of LV relaxation by untwisting rate: a new isovolumic phase measure of tau. Am J Physiol Heart Circ Physiol. 2001;281:H2002–9.PubMed
60.••
Opdahl A, Remme EW, Helle-Valle T, et al. Myocardial relaxation, restoring forces, and early-diastolic load are independent determinants of left ventricular untwisting rate. Circulation. 2012;126:1441–51. An important study looking at the hemodynamic determinants of LV untwisting rate.CrossRefPubMed
61.
Wang J, Khoury DS, Yue Y, et al. Left ventricular untwisting rate by speckle tracking echocardiography. Circulation. 2007;116:2580–6.CrossRefPubMed
62.
Abhayaratna WP, Seward JB, Appleton CP, et al. Left atrial size: physiologic determinants and clinical applications. J Am Coll Cardiol. 2006;47:2357–63.CrossRefPubMed
63.
Pritchett AM, Mahoney DW, Jacobsen SJ, et al. Diastolic dysfunction and left atrial volume: a population-based study. J Am Coll Cardiol. 2005;45:87–92.CrossRefPubMed
64.
Tsang TS, Abhayaratna WP, Barnes ME, et al. Prediction of cardiovascular outcomes with left atrial size: is volume superior to area or diameter? J Am Coll Cardiol. 2006;47:1018–23.CrossRefPubMed
65.••
Mor-Avi V, Yodwut C, Jenkins C, et al. Real-time 3D echocardiographic quantification of left atrial volume: multicenter study for validation with CMR. JACC Cardiovasc Imaging. 2012;5:769–77. Important study looking at multicenter LA volume measurements with validation against CMR.CrossRefPubMed
66.
Kurt M, Wang J, Torre-Amione G, et al. Left atrial function in diastolic heart failure. Circ Cardiovasc Imaging. 2009;2:10–5.CrossRefPubMed
67.
Wakami K, Ohte N, Asada K, et al. Correlation between left ventricular end-diastolic pressure and peak left atrial wall strain during left ventricular systole. J Am Soc Echocardiogr. 2009;22:847–51.CrossRefPubMed
68.
Di Salvo G, Caso P, Lo Piccolo R, et al. Atrial myocardial deformation properties predict maintenance of sinus rhythm after external cardioversion of recent-onset lone atrial fibrillation: a color Doppler myocardial imaging and transthoracic and transesophageal echocardiographic study. Circulation. 2005;112:387–95.CrossRefPubMed
Metadaten
Titel
Echocardiographic Evaluation of Left Ventricular Diastolic Function: an Update
verfasst von
Dimitrios Maragiannis
Sherif F. Nagueh
Publikationsdatum
01.02.2015
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 2/2015
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-014-0561-9

Weitere Artikel der Ausgabe 2/2015

Current Cardiology Reports 2/2015 Zur Ausgabe

Ischemic Heart Disease (D Mukherjee, Section Editor)

Statins and Cognitive Function: an Updated Review

Ischemic Heart Disease (D Mukherjee, Section Editor)

Bypass Grafting Versus Percutaneous Intervention in Multivessel Coronary Disease: the Current State

Ischemic Heart Disease (D Mukherjee, Section Editor)

Health Resource Variability in the Achievement of Optimal Performance and Clinical Outcome in Ischemic Heart Disease

Hypertension (WB White and AJ Peixoto, Section Editors)

Managing Hypertension with Ambulatory Blood Pressure Monitoring

Echocardiography (JM Gardin, Section Editor)

The Role of Echocardiography in Hypertrophic Cardiomyopathy

Ischemic Heart Disease (D Mukherjee, Section Editor)

Chest Pain Characteristics and Gender in the Early Diagnosis of Acute Myocardial Infarction

Neu im Fachgebiet Kardiologie

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

17.05.2024 Plötzlicher Herztod Nachrichten

Ein signifikanter Anteil der Fälle von plötzlichem Herztod ist genetisch bedingt. Um ihre Verwandten vor diesem Schicksal zu bewahren, sollten jüngere Personen, die plötzlich unerwartet versterben, ausnahmslos einer Autopsie unterzogen werden.

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

17.05.2024 Vorhofflimmern Nachrichten

Nicht nur ein vergrößerter, sondern auch ein kleiner linker Ventrikel ist bei Vorhofflimmern mit einer erhöhten Komplikationsrate assoziiert. Der Zusammenhang besteht nach Daten aus China unabhängig von anderen Risikofaktoren.

Semaglutid bei Herzinsuffizienz: Wie erklärt sich die Wirksamkeit?

17.05.2024 Herzinsuffizienz Nachrichten

Bei adipösen Patienten mit Herzinsuffizienz des HFpEF-Phänotyps ist Semaglutid von symptomatischem Nutzen. Resultiert dieser Benefit allein aus der Gewichtsreduktion oder auch aus spezifischen Effekten auf die Herzinsuffizienz-Pathogenese? Eine neue Analyse gibt Aufschluss.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen
Bildnachweise