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Erschienen in: Forensic Science, Medicine and Pathology 2/2014

01.06.2014 | Original Article

The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 2/2014

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Abstract

The clavicle plays an important role for forensic age estimation in living individuals, particularly with regard to the age of majority. The present prospective study aims to evaluate the age-dependent ossification process of the medial clavicular epiphysis in order to establish the clavicular sub-stages introduced in 2010 as well as the advantages and possibilities of thin-slice computed tomography (CT). For this purpose, 0.6 mm thin-slice CT scans of sternoclavicular joints of 572 bodies aged between 10 and 40 years were evaluated by means of two complementary classification systems: a five-stage system and a sub-staging system for the main stages 2 and 3. Assessment was possible in 493 cases. The results for stages 4 and 5 are in line with previous studies that found the ages of 21 years and 26 years, respectively, as minimum ages for these stages. Sub-stage 3c was first found at the age of 19 years in both sexes, thereby corroborating the value of this sub-stage as to statements about the age of majority. In comparison to other CT studies, stage 3a was first observed ~1 year earlier (16.4 years in males and 15.5 years in females). Stage 2c only occurred in 3 cases. In conclusion, the data corroborate the significance of diagnosing sub-stages as well as the value of thin-slice CT. For forensic practice, the concomitant and complementary use of both classification systems applied in this study can be recommended.
Literatur
1.
Zurück zum Zitat Schmeling A, Reisinger W, Geserick G, Olze A. The current state of forensic age estimation of live subjects for the purpose of criminal prosecution. Forensic Sci Med Pathol. 2005;1:239–46.CrossRef Schmeling A, Reisinger W, Geserick G, Olze A. The current state of forensic age estimation of live subjects for the purpose of criminal prosecution. Forensic Sci Med Pathol. 2005;1:239–46.CrossRef
2.
Zurück zum Zitat Olze A, van Niekerk P, Ishikawa T, Zhu BL, Schulz R, Maeda H, Schmeling A. Comparative study on the effect of ethnicity on wisdom tooth eruption. Int J Legal Med. 2007;121:445–8.PubMedCrossRef Olze A, van Niekerk P, Ishikawa T, Zhu BL, Schulz R, Maeda H, Schmeling A. Comparative study on the effect of ethnicity on wisdom tooth eruption. Int J Legal Med. 2007;121:445–8.PubMedCrossRef
3.
Zurück zum Zitat Thevissen PW, Kaur J, Willems G. Human age estimation combining third molar and skeletal development. Int J Legal Med. 2012;126:285–92.PubMedCrossRef Thevissen PW, Kaur J, Willems G. Human age estimation combining third molar and skeletal development. Int J Legal Med. 2012;126:285–92.PubMedCrossRef
4.
Zurück zum Zitat Olze A, van Niekerk P, Schulz R, Ribbecke S, Schmeling A. The influence of impaction on the rate of third molar mineralisation in male black Africans. Int J Legal Med. 2012;126:869–74.PubMedCrossRef Olze A, van Niekerk P, Schulz R, Ribbecke S, Schmeling A. The influence of impaction on the rate of third molar mineralisation in male black Africans. Int J Legal Med. 2012;126:869–74.PubMedCrossRef
5.
Zurück zum Zitat Cameriere R, Cingolani M, Giuliodori A, De Luca S, Ferrante L. Radiographic analysis of epiphyseal fusion at knee joint to assess likelihood of having attained 18 years of age. Int J Legal Med. 2012;126:889–99.PubMedCrossRef Cameriere R, Cingolani M, Giuliodori A, De Luca S, Ferrante L. Radiographic analysis of epiphyseal fusion at knee joint to assess likelihood of having attained 18 years of age. Int J Legal Med. 2012;126:889–99.PubMedCrossRef
6.
Zurück zum Zitat Wittschieber D, Schmeling A, Schmidt S, Heindel W, Pfeiffer H, Vieth V. The Risser sign for forensic age estimation in living individuals: a study of 643 pelvic radiographs. Forensic Sci Med Pathol. 2013;9:36–43.PubMedCrossRef Wittschieber D, Schmeling A, Schmidt S, Heindel W, Pfeiffer H, Vieth V. The Risser sign for forensic age estimation in living individuals: a study of 643 pelvic radiographs. Forensic Sci Med Pathol. 2013;9:36–43.PubMedCrossRef
7.
Zurück zum Zitat Wittschieber D, Vieth V, Wierer T, Pfeiffer H, Schmeling A. Cameriere’s approach modified for pelvic radiographs: a novel method to assess apophyseal iliac crest ossification for the purpose of forensic age diagnostics. Int J Legal Med. 2013;127:825–9.PubMedCrossRef Wittschieber D, Vieth V, Wierer T, Pfeiffer H, Schmeling A. Cameriere’s approach modified for pelvic radiographs: a novel method to assess apophyseal iliac crest ossification for the purpose of forensic age diagnostics. Int J Legal Med. 2013;127:825–9.PubMedCrossRef
8.
Zurück zum Zitat Schulz R, Schiborr M, Pfeiffer H, Schmidt S, Schmeling A. Sonographic assessment of the ossification of the medial clavicular epiphysis in 616 individuals. Forensic Sci Med Pathol. 2013; doi: 10.1007/s12024-013-9440-8. Schulz R, Schiborr M, Pfeiffer H, Schmidt S, Schmeling A. Sonographic assessment of the ossification of the medial clavicular epiphysis in 616 individuals. Forensic Sci Med Pathol. 2013; doi: 10.​1007/​s12024-013-9440-8.
9.
Zurück zum Zitat Schmidt S, Nitz I, Ribbecke S, Schulz R, Pfeiffer H, Schmeling A. Skeletal age determination of the hand: a comparison of methods. Int J Legal Med. 2013;127:691–8.PubMedCrossRef Schmidt S, Nitz I, Ribbecke S, Schulz R, Pfeiffer H, Schmeling A. Skeletal age determination of the hand: a comparison of methods. Int J Legal Med. 2013;127:691–8.PubMedCrossRef
10.
Zurück zum Zitat Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rösing FW, Rötzscher K, Geserick G. Criteria for age estimation in living individuals. Int J Legal Med. 2008;122:457–60.PubMedCrossRef Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rösing FW, Rötzscher K, Geserick G. Criteria for age estimation in living individuals. Int J Legal Med. 2008;122:457–60.PubMedCrossRef
11.
Zurück zum Zitat Gunst K, Mesotten K, Carbonez A, Willems G. Third molar root development in relation to chronological age: a large sample sized retrospective study. Forensic Sci Int. 2003;136:52–7.PubMedCrossRef Gunst K, Mesotten K, Carbonez A, Willems G. Third molar root development in relation to chronological age: a large sample sized retrospective study. Forensic Sci Int. 2003;136:52–7.PubMedCrossRef
12.
Zurück zum Zitat Knell B, Ruhstaller P, Prieels F, Schmeling A. Dental age diagnostics by means of radiographical evaluation of the growth stages of lower wisdom teeth. Int J Legal Med. 2009;123:465–9.PubMedCrossRef Knell B, Ruhstaller P, Prieels F, Schmeling A. Dental age diagnostics by means of radiographical evaluation of the growth stages of lower wisdom teeth. Int J Legal Med. 2009;123:465–9.PubMedCrossRef
13.
Zurück zum Zitat Tisè M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A. Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med. 2011;125:411–6.PubMedCrossRef Tisè M, Mazzarini L, Fabrizzi G, Ferrante L, Giorgetti R, Tagliabracci A. Applicability of Greulich and Pyle method for age assessment in forensic practice on an Italian sample. Int J Legal Med. 2011;125:411–6.PubMedCrossRef
14.
Zurück zum Zitat Schulz R, Mühler M, Reisinger W, Schmidt S, Schmeling A. Radiographic staging of ossification of the medial clavicular epiphysis. Int J Legal Med. 2008;122:55–8.PubMedCrossRef Schulz R, Mühler M, Reisinger W, Schmidt S, Schmeling A. Radiographic staging of ossification of the medial clavicular epiphysis. Int J Legal Med. 2008;122:55–8.PubMedCrossRef
15.
Zurück zum Zitat Mühler M, Schulz R, Schmidt S, Schmeling A, Reisinger W. The influence of slice thickness on assessment of clavicle ossification in forensic age diagnostics. Int J Legal Med. 2006;120:15–7.PubMedCrossRef Mühler M, Schulz R, Schmidt S, Schmeling A, Reisinger W. The influence of slice thickness on assessment of clavicle ossification in forensic age diagnostics. Int J Legal Med. 2006;120:15–7.PubMedCrossRef
16.
Zurück zum Zitat Kreitner KF, Schweden F, Schild HH, Riepert T, Nafe B. Computerized tomography of the epiphyseal union of the medial clavicle: an auxiliary method of age determination during adolescence and the 3rd decade of life? Rofo. 1997;166:481–6.PubMedCrossRef Kreitner KF, Schweden F, Schild HH, Riepert T, Nafe B. Computerized tomography of the epiphyseal union of the medial clavicle: an auxiliary method of age determination during adolescence and the 3rd decade of life? Rofo. 1997;166:481–6.PubMedCrossRef
17.
Zurück zum Zitat Schmeling A, Schulz R, Reisinger W, Mühler M, Wernecke KD, Geserick G. Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med. 2004;118:5–8.PubMedCrossRef Schmeling A, Schulz R, Reisinger W, Mühler M, Wernecke KD, Geserick G. Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med. 2004;118:5–8.PubMedCrossRef
18.
Zurück zum Zitat Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A. Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med. 2010;124:149–54.PubMedCrossRef Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A. Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med. 2010;124:149–54.PubMedCrossRef
19.
Zurück zum Zitat Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A. Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med. 2010;124:321–5.PubMedCrossRef Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A. Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med. 2010;124:321–5.PubMedCrossRef
20.
Zurück zum Zitat Bassed RB, Briggs C, Drummer OH. The incidence of asymmetrical left/right skeletal and dental development in an Australian population and the effect of this on forensic age estimations. Int J Legal Med. 2012;126:251–7.PubMedCrossRef Bassed RB, Briggs C, Drummer OH. The incidence of asymmetrical left/right skeletal and dental development in an Australian population and the effect of this on forensic age estimations. Int J Legal Med. 2012;126:251–7.PubMedCrossRef
21.
Zurück zum Zitat Schulz R, Mühler M, Mutze S, Schmidt S, Reisinger W, Schmeling A. Studies on the time frame for ossification of the medial epiphysis of the clavicle as revealed by CT scans. Int J Legal Med. 2005;119:142–5.PubMedCrossRef Schulz R, Mühler M, Mutze S, Schmidt S, Reisinger W, Schmeling A. Studies on the time frame for ossification of the medial epiphysis of the clavicle as revealed by CT scans. Int J Legal Med. 2005;119:142–5.PubMedCrossRef
22.
Zurück zum Zitat Kreitner KF, Schweden FJ, Riepert T, Nafe B, Thelen M. Bone age determination based on the study of the medial extremity of the clavicle. Eur Radiol. 1998;8:1116–22.PubMedCrossRef Kreitner KF, Schweden FJ, Riepert T, Nafe B, Thelen M. Bone age determination based on the study of the medial extremity of the clavicle. Eur Radiol. 1998;8:1116–22.PubMedCrossRef
23.
Zurück zum Zitat Jit I, Kullkarni M. Times of appearance and fusion of epiphysis at the medial end of the clavicle. Indian J Med Res. 1976;64:773–82.PubMed Jit I, Kullkarni M. Times of appearance and fusion of epiphysis at the medial end of the clavicle. Indian J Med Res. 1976;64:773–82.PubMed
24.
Zurück zum Zitat Owings Webb PA, Myers Suchey J. Epiphyseal union of the anterior iliac crest and medial clavicle in a modern multiracial sample of American males and females. Am J Phys Anthropol. 1985;68:457–66.CrossRef Owings Webb PA, Myers Suchey J. Epiphyseal union of the anterior iliac crest and medial clavicle in a modern multiracial sample of American males and females. Am J Phys Anthropol. 1985;68:457–66.CrossRef
25.
Zurück zum Zitat Bassed RB, Drummer OH, Briggs C, Valenzuela A. Age estimation and the medial clavicular epiphysis: analysis of the age of majority in an Australian population using computed tomography. Forensic Sci Med Pathol. 2011;7:148–54.PubMedCrossRef Bassed RB, Drummer OH, Briggs C, Valenzuela A. Age estimation and the medial clavicular epiphysis: analysis of the age of majority in an Australian population using computed tomography. Forensic Sci Med Pathol. 2011;7:148–54.PubMedCrossRef
26.
Zurück zum Zitat Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G. Effects of ethnicity on skeletal maturation: consequences for forensic age estimations. Int J Legal Med. 2000;113:253–8.PubMedCrossRef Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G. Effects of ethnicity on skeletal maturation: consequences for forensic age estimations. Int J Legal Med. 2000;113:253–8.PubMedCrossRef
27.
Zurück zum Zitat Meijerman L, Maat GJ, Schulz R, Schmeling A. Variables affecting the probability of complete fusion of the medial clavicular epiphysis. Int J Legal Med. 2007;121:463–8.PubMedCentralPubMedCrossRef Meijerman L, Maat GJ, Schulz R, Schmeling A. Variables affecting the probability of complete fusion of the medial clavicular epiphysis. Int J Legal Med. 2007;121:463–8.PubMedCentralPubMedCrossRef
28.
Zurück zum Zitat Schmeling A, Schulz R, Danner B, Rösing FW. The impact of economic progress and modernization in medicine on the ossification of hand and wrist. Int J Legal Med. 2006;120:121–6.PubMedCrossRef Schmeling A, Schulz R, Danner B, Rösing FW. The impact of economic progress and modernization in medicine on the ossification of hand and wrist. Int J Legal Med. 2006;120:121–6.PubMedCrossRef
29.
30.
Zurück zum Zitat Schmidt S, Mühler M, Schmeling A, Reisinger W, Schulz R. Magnetic resonance imaging of the clavicular ossification. Int J Legal Med. 2007;121:321–4.PubMedCrossRef Schmidt S, Mühler M, Schmeling A, Reisinger W, Schulz R. Magnetic resonance imaging of the clavicular ossification. Int J Legal Med. 2007;121:321–4.PubMedCrossRef
31.
Zurück zum Zitat Garamendi PM, Landa MI, Botella MC, Alemán I. Forensic age estimation on digital X-ray images: medial epiphyses of the clavicle and first rib ossification in relation to chronological age. J Forensic Sci. 2011;56(Suppl 1):S3–12.PubMedCrossRef Garamendi PM, Landa MI, Botella MC, Alemán I. Forensic age estimation on digital X-ray images: medial epiphyses of the clavicle and first rib ossification in relation to chronological age. J Forensic Sci. 2011;56(Suppl 1):S3–12.PubMedCrossRef
32.
Zurück zum Zitat Schulze D, Rother U, Fuhrmann A, Richel S, Faulmann G, Heiland M. Correlation of age and ossification of the medial clavicular epiphysis using computed tomography. Forensic Sci Int. 2006;158:184–9.PubMedCrossRef Schulze D, Rother U, Fuhrmann A, Richel S, Faulmann G, Heiland M. Correlation of age and ossification of the medial clavicular epiphysis using computed tomography. Forensic Sci Int. 2006;158:184–9.PubMedCrossRef
Metadaten
Titel
The value of sub-stages and thin slices for the assessment of the medial clavicular epiphysis: a prospective multi-center CT study
Publikationsdatum
01.06.2014
Erschienen in
Forensic Science, Medicine and Pathology / Ausgabe 2/2014
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-013-9511-x

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