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Head and Neck Pathology

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01.09.2008 | Case Report

Hybrid Central Odontogenic Fibroma with Giant Cell Granuloma-like Component: Case Report and Review of Literature

verfasst von: Rania H. Younis, Mark A. Scheper, C. C. Lindquist, Bernard Levy

Erschienen in: Head and Neck Pathology | Ausgabe 3/2008

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Abstract

Central odontogenic fibroma (COF) is a rare benign ectomesenchymal tumor of the jaws. Only 12 cases of COF with giant cell granuloma (GCG)-like lesion have been reported in the English literature. Here, we present a new case of COF epithelium rich type with a GCG-like component. Radiographically, this lesion presented as a well defined unilocular radiolucency in the body of the mandible. Histologically, the lesion showed a unique confluence of odontogenic epithelial rests with multinucleated giant cells (MNGCs) in a highly cellular fibrous connective tissue stroma, with osteoid and cementoid deposits. A distinct area showed the typical histological picture of each component separately. Immunohistochemical staining with pancytokeratin (CK) highlighted the odontogenic epithelial component merging with the GCG component throughout most of the lesion. The significance of GCG-like areas within COF is the reported increased risk of recurrence following curettage, possibly necessitating more aggressive therapy.

Barnes EL, Eveson JW, Reichart P, Sidransky D, editors. Pathology and genetics of head and neck tumors. Philipsen HP, Reichart PA, Sciubba JJ, Van der Waal I, series editors. Odontogenic tumors World Health Organization classification of tumors. Lyon, France: IARC Press, 2005. p. 315.

Neville BW, Damm DD, Allen CM, Bouquot JE, editors. Oral and maxillofacial pathology. Philadelphia: Saunders: 2002. p. 633–4.

Kim J, Ellis GL. Dental follicular tissue misinterpretation as odontogenic tumors. J Oral Maxillofac Surg. 1993;51:762–7.PubMedCrossRef

Brannon RB. Central odontogenic fibroma, myxoma (odontogenic myxoma, fibromyxoma), and central odontogenic granular cell tumor. Oral Maxillofac Surg Clin North Am. 2004;16:359–74.PubMedCrossRef

Wesley RK, Wysocki GP, Mintz SM. The central odontogenic fibroma. Clinical and morphologic studies. Oral Surg Oral Med Oral Pathol. 1975;40:235–45.CrossRef

Shafer WG, Hine MK, Levy BM, editors. A text book of oral pathology. Philadelphia: Saunders: 1983. p. 294–5.

Gardner DG. The central odontogenic fibroma: an attempt at clarification. Oral Surg Oral Med Oral Pathol. 1980;50:425–32.PubMedCrossRef

Kramer IRH, Pindborg JJ, Shear M, editors. Histological typing of odontogenic tumors: international histological classification of tumors World Health Organization. Berlin: Springer-Verlag: 1992. p. 22.

Dunlap CL, Barker BF. Central odontogenic fibroma of the WHO type. Oral Surg Oral Med Oral Pathol. 1984;57:390–4.PubMedCrossRef

10.

Gardner DG. Central odontogenic fibroma current concepts. J Oral Pathol Med. 1996;25(10):556–61.PubMedCrossRef

11.

Regezi JA, Scuibba JJ, Jordan RCK, editors. Oral pathology: clinical pathologic correlations. Missouri: Saunders: 2003. p. 280–1.

12.

Ramer M, Buonocore P, Krost B. Central odontogenic fibroma. Report of a case and review of literature. Periodontal clin investing. 2002;24:27–30.

13.

Drebber U, Scheer M, Zöller JE, et al. The central odontogenic fibroma a rare tumor. Pathologe. 2003;24:136–40.PubMed

14.

Daniels JS. Central odontogenic fibroma of mandible a case report and review of the literature. Oral Surg Oral Med Oral Pathol. 2004;98:295–300.

15.

Covani U, Crespi R, Perrini N, et al. Central odontogenic fibroma: a case report. Med Oral Patol Oral Cir Bucal. 2005.10 Suppl2:E154–7.

16.

Ikeshima A, Utsunomiya T. Case report of intraosseous fibroma: a study on odontogenic and desmoplastic fibromas with a review of the literature. J oral Sci. 2005;47:149–57.PubMedCrossRef

17.

Cicconetti A, Bartoli A, Tallarico M, et al. Central odontogenic fibroma interesting the maxillary sinus a case report and literature survey. Minerva Stomatol. 2006;55:229–39.PubMed

18.

Cercadillo-Ibarguren I, Berini-Aytés L, Marco-Molina V, et al. Locally aggressive central odontogenic fibroma associated to an inflammatory cyst: a clinical, histological and immunohistochemical study. J Oral Pathol Med. 2006;35:513–6.PubMedCrossRef

19.

Buchner A, Merrell PW, Carpenter WM. Relative frequency of central odontogenic tumors: a study of 1, 088 cases from northern California and comparison to studies from other parts of the world. J Oral Maxillofac Surg. 2006;64:1343–52.PubMedCrossRef

20.

Silva CO, Sallum AW, do Couto-Filho CE, et al. Localized gingival enlargement associated with alveolar process expansion: peripheral ossifying fibroma coincident with central odontogenic fibroma. J Periodontol. 2007;78:1354–59.PubMedCrossRef

21.

Kaffe I, Buchner A. Radiologic features of central odontogenic fibroma. Oral Surg Oral Med Oral Pathol. 1994;78:811–8.PubMedCrossRef

22.

Allen CM, Hammond HL, Stimson PG. Central odontogenic fibroma, WHO type. A report of three cases with an unusual associated giant cell reaction. Oral Surg Oral Med Oral Pathol. 1992;73:62–6.PubMedCrossRef

23.

Odell EW, Lombardi T, Barrett AW, et al. Hybrid central giant cell granuloma and central odontogenic fibroma-like lesions of the jaws. Histopathology. 1997;30:165–71.PubMedCrossRef

24.

Mosqueda TA, Bermúdez FV, Díaz Franco MA. Combined central odontogenic fibroma and giant cell granuloma-like lesion of the mandible: report of a case and review of the literature. J Oral Maxillofac Surg. 1999;57:1258–62.CrossRef

25.

Calvo N, Alonso D, Prieto M, et al. Central odontogenic fibroma granular cell variant: a case report and review of the literature. J Oral Maxillofac Surg. 2002;60:1192–4.PubMedCrossRef

26.

Günhan O, Gürbüzer B, Gardner DG, et al. A central odontogenic fibroma exhibiting pleomorphic fibroblasts and numerous calcifications. Br J Oral Maxillofac Surg. 1991;29:42–3.PubMedCrossRef

27.

Dunlap CL. Odontogenic fibroma. Semin Diagn Pathol. 1999;16(4):293–6.PubMed

28.

Handlers JP, Abrams AM, Melrose RJ, et al. Central odontogenic fibroma: clinicopathologic features of 19 cases and review of the literature. J Oral Maxillofac Surg. 1991;49:46–54.PubMedCrossRef

29.

Heimdal A, Isacsson G, Nilsson L. Recurrent central odontogenic fibroma. Oral Surg Oral Med Oral Pathol. 1980;50:140–5.PubMedCrossRef

30.

Kaffe I, Ardekian L, Taicher S, et al. Radiologic features of central giant cell granuloma of the jaws. Oral Surg Oral Med Oral Pathol. 1996;81:720–6.

31.

Bataineh AB, Al-Khateeb T, Rawashdeh MA. The surgical treatment of central giant cell granuloma of the mandible. J Oral Maxillofac Surg. 2002;60:756–61.PubMedCrossRef

32.

Rawashdeh MA, Bataineh AB, Al-Khateeb T. Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla. Int J Oral Maxillofac Surg. 2006;35:60–6.PubMedCrossRef

33.

Regezi JA. Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws. Mod Pathol. 2002;15:331–41.PubMedCrossRef

34.

Sciubba JJ, Fantasia JE, Kahn LB, editors. Atlas of tumor pathology: tumors and cysts of the jaw. Washington, DC: Armed Forces Institute of Pathology: 2001. p. 161–6.

35.

Ide F, Sakashita H, Kusama K. Ameloblastomatoid, central odontogenic fibroma: an epithelium-rich variant. J Oral Pathol Med. 2002;31(10):612–4.PubMedCrossRef

36.

Wolvius EB, De Lange J, Smeets EE, et al. Noonan-like/multiple giant cell lesion syndrome. Report of a case and review of the literature. J oral maxillofac surg. 2006;64:1289–92.PubMedCrossRef

37.

Stypulkowska J. Odontogenic tumors and neoplastic-like changes of the jaw bone. Clinical study and evalutation of treatment results. Folia Med Cracov. 1998;39(1–2):35–141.PubMed

38.

Ficarra G, Sapp JP, Eversole LR. Multiple peripheral odontogenic fibroma, World Health Organization type, and central giant cell granuloma: a case report of an unusual association. J Oral Maxillofac Surg. 1993;51:325–8.PubMedCrossRef

39.

Larbcharoensub N, Pongtippan A, Tuntiyatorn L, et al. Giant cell reparative granuloma concurrent with squamous cell carcinoma of the temporal bone: a case report and review of the literature. J Med Assoc Thai. 2007;90:369–75.PubMed

40.

Sciubba JJ, Fantasia JE, Kahn LB, editors. Atlas of tumor pathology: tumors and cysts of the jaw. Washington DC: Armed Forces Institute of Pathology: 2001. p. 170–3.

41.

Sholapurkar AA, Pai KM, Ahsan A. Central giant cell granuloma of the anterior maxilla. Indian J Dent Res. 2008;19:78–82.PubMedCrossRef

Titel: Hybrid Central Odontogenic Fibroma with Giant Cell Granuloma-like Component: Case Report and Review of Literature
verfasst von: Rania H. Younis
Mark A. Scheper
C. C. Lindquist
Bernard Levy
Publikationsdatum: 01.09.2008
Verlag: Humana Press Inc
Erschienen in: Head and Neck Pathology / Ausgabe 3/2008
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-008-0063-4

Springer Medizin

Hybrid Central Odontogenic Fibroma with Giant Cell Granuloma-like Component: Case Report and Review of Literature

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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