Skip to main content
Erschienen in: Head and Neck Pathology 4/2009

01.12.2009 | Case Report

Tumor-to-Tumor Metastasis: Renal Cell Carcinoma Metastatic to Papillary Carcinoma of Thyroid—Report of a Case and Review of the Literature

verfasst von: Olga L. Bohn, Luis E. De las Casas, Marino E. Leon

Erschienen in: Head and Neck Pathology | Ausgabe 4/2009

Einloggen, um Zugang zu erhalten

Abstract

Metastatic disease to thyroid gland is a rare event. Although renal cell carcinoma (RCC) has been reported to metastasize the thyroid gland, metastatic RCC to a thyroid neoplasm is very unusual. We report a case of a 68-year-old man with history of RCC who presented with a 2.5-cm thyroid nodule. Histologic examination demonstrates a renal cell carcinoma metastatic to a papillary carcinoma of the thyroid. The clinicopathologic features of metastatic disease into a thyroid gland neoplasm are shown, and a review of the literature is presented.
Literatur
1.
Zurück zum Zitat Shimaoka K, Sokal JE, Pickren JW. Metastatic neoplasms in the thyroid gland. Pathological and clinical findings. Cancer. 1962;15:557–65.CrossRefPubMed Shimaoka K, Sokal JE, Pickren JW. Metastatic neoplasms in the thyroid gland. Pathological and clinical findings. Cancer. 1962;15:557–65.CrossRefPubMed
2.
Zurück zum Zitat Rizzo M, Rossi RT, Bonaffini O, et al. Thyroid metastasis of clear cell renal carcinoma: report of a case. Diagn Cytopathol. 2009. Rizzo M, Rossi RT, Bonaffini O, et al. Thyroid metastasis of clear cell renal carcinoma: report of a case. Diagn Cytopathol. 2009.
3.
Zurück zum Zitat Lam KY, Lo CY. Metastatic tumors of the thyroid gland: a study of 79 cases in Chinese patients. Arch Pathol Lab Med. 1998;122(1):37–41.PubMed Lam KY, Lo CY. Metastatic tumors of the thyroid gland: a study of 79 cases in Chinese patients. Arch Pathol Lab Med. 1998;122(1):37–41.PubMed
4.
Zurück zum Zitat Lin JD, Weng HF, Ho YS. Clinical and pathological characteristics of secondary thyroid cancer. Thyroid. 1998;8(2):149–53.CrossRefPubMed Lin JD, Weng HF, Ho YS. Clinical and pathological characteristics of secondary thyroid cancer. Thyroid. 1998;8(2):149–53.CrossRefPubMed
5.
Zurück zum Zitat Haugen BR, Nawaz S, Cohn A, et al. Secondary malignancy of the thyroid gland: a case report and review of the literature. Thyroid. 1994;4(3):297–300.CrossRefPubMed Haugen BR, Nawaz S, Cohn A, et al. Secondary malignancy of the thyroid gland: a case report and review of the literature. Thyroid. 1994;4(3):297–300.CrossRefPubMed
6.
Zurück zum Zitat Heffess CS, Wenig BM, Thompson LD. Metastatic renal cell carcinoma to the thyroid gland: a clinicopathologic study of 36 cases. Cancer. 2002;95(9):1869–78.CrossRefPubMed Heffess CS, Wenig BM, Thompson LD. Metastatic renal cell carcinoma to the thyroid gland: a clinicopathologic study of 36 cases. Cancer. 2002;95(9):1869–78.CrossRefPubMed
7.
Zurück zum Zitat Green LK, Ro JY, Mackay B, Ayala AG, Luna MA. Renal cell carcinoma metastatic to the thyroid. Cancer. 1989;63(9):1810–5.CrossRefPubMed Green LK, Ro JY, Mackay B, Ayala AG, Luna MA. Renal cell carcinoma metastatic to the thyroid. Cancer. 1989;63(9):1810–5.CrossRefPubMed
8.
Zurück zum Zitat Czech JM, Lichtor TR, Carney JA, van Heerden JA. Neoplasms metastatic to the thyroid gland. Surg Gynecol Obstet. 1982;155(4):503–5.PubMed Czech JM, Lichtor TR, Carney JA, van Heerden JA. Neoplasms metastatic to the thyroid gland. Surg Gynecol Obstet. 1982;155(4):503–5.PubMed
9.
Zurück zum Zitat Elliott RH Jr, Frantz VK. Metastatic carcinoma masquerading as primary thyroid cancer: a report of authors’ 14 cases. Ann Surg. 1960;151:551–61.CrossRefPubMed Elliott RH Jr, Frantz VK. Metastatic carcinoma masquerading as primary thyroid cancer: a report of authors’ 14 cases. Ann Surg. 1960;151:551–61.CrossRefPubMed
10.
Zurück zum Zitat Ivy HK. Cancer metastatic to the thyroid: a diagnostic problem. Mayo Clin Proc. 1984;59(12):856–9.PubMed Ivy HK. Cancer metastatic to the thyroid: a diagnostic problem. Mayo Clin Proc. 1984;59(12):856–9.PubMed
11.
Zurück zum Zitat Carcangiu ML, Sibley RK, Rosai J. Clear cell change in primary thyroid tumors. A study of 38 cases. Am J Surg Pathol. 1985;9(10):705–22.CrossRefPubMed Carcangiu ML, Sibley RK, Rosai J. Clear cell change in primary thyroid tumors. A study of 38 cases. Am J Surg Pathol. 1985;9(10):705–22.CrossRefPubMed
12.
Zurück zum Zitat Rosai J, Carcangiu ML, DeLellis R. Tumors of the thyroid gland. Washington, DC: Armed Forces Institute of Pathology; 1992. p. 289–96. Rosai J, Carcangiu ML, DeLellis R. Tumors of the thyroid gland. Washington, DC: Armed Forces Institute of Pathology; 1992. p. 289–96.
13.
Zurück zum Zitat Ryska A, Cap J. Tumor-to-tumor metastasis of renal cell carcinoma into oncocytic carcinoma of the thyroid. Report of a case and review of the literature. Pathol Res Pract. 2003;199(2):101–6.PubMed Ryska A, Cap J. Tumor-to-tumor metastasis of renal cell carcinoma into oncocytic carcinoma of the thyroid. Report of a case and review of the literature. Pathol Res Pract. 2003;199(2):101–6.PubMed
14.
Zurück zum Zitat Qian L, Pucci R, Castro CY, Eltorky MA. Renal cell carcinoma metastatic to Hurthle cell adenoma of thyroid. Ann Diagn Pathol. 2004;8(5):305–8.CrossRefPubMed Qian L, Pucci R, Castro CY, Eltorky MA. Renal cell carcinoma metastatic to Hurthle cell adenoma of thyroid. Ann Diagn Pathol. 2004;8(5):305–8.CrossRefPubMed
15.
Zurück zum Zitat Koo HL, Jang J, Hong SJ, Shong Y, Gong G. Renal cell carcinoma metastatic to follicular adenoma of the thyroid gland. A case report. Acta Cytol. 2004;48(1):64–8.PubMed Koo HL, Jang J, Hong SJ, Shong Y, Gong G. Renal cell carcinoma metastatic to follicular adenoma of the thyroid gland. A case report. Acta Cytol. 2004;48(1):64–8.PubMed
16.
Zurück zum Zitat Baloch ZW, LiVolsi VA. Tumor-to-tumor metastasis to follicular variant of papillary carcinoma of thyroid. Arch Pathol Lab Med. 1999;123(8):703–6.PubMed Baloch ZW, LiVolsi VA. Tumor-to-tumor metastasis to follicular variant of papillary carcinoma of thyroid. Arch Pathol Lab Med. 1999;123(8):703–6.PubMed
17.
Zurück zum Zitat Wolf G, Aigner RM, Humer-Fuchs U, Schwarz T, Krippl P, Wehrschuetz M. Renal cell carcinoma metastasis in a microfollicular adenoma of the thyroid gland. Acta Med Austriaca. 2002;29(4):141–2.CrossRefPubMed Wolf G, Aigner RM, Humer-Fuchs U, Schwarz T, Krippl P, Wehrschuetz M. Renal cell carcinoma metastasis in a microfollicular adenoma of the thyroid gland. Acta Med Austriaca. 2002;29(4):141–2.CrossRefPubMed
18.
Zurück zum Zitat Rabson SM, Stier PL, Baumgartner JC, Rosenbaum D. Metastasis of cancer to cancer. Am J Clin Pathol. 1954;24(5):572–9.PubMed Rabson SM, Stier PL, Baumgartner JC, Rosenbaum D. Metastasis of cancer to cancer. Am J Clin Pathol. 1954;24(5):572–9.PubMed
19.
Zurück zum Zitat Campbell LV Jr, Gilbert E, Chamberlain CR Jr, Watne AL. Metastases of cancer to cancer. Cancer. 1968;22(3):635–43.CrossRefPubMed Campbell LV Jr, Gilbert E, Chamberlain CR Jr, Watne AL. Metastases of cancer to cancer. Cancer. 1968;22(3):635–43.CrossRefPubMed
20.
Zurück zum Zitat Dobbing J. Cancer to cancer. Guys Hosp Rep. 1958;107(1):60–5.PubMed Dobbing J. Cancer to cancer. Guys Hosp Rep. 1958;107(1):60–5.PubMed
21.
Zurück zum Zitat Holland JM. Proceedings: cancer of the kidney–natural history and staging. Cancer. 1973;32(5):1030–42.CrossRefPubMed Holland JM. Proceedings: cancer of the kidney–natural history and staging. Cancer. 1973;32(5):1030–42.CrossRefPubMed
22.
Zurück zum Zitat Nakhjavani MK, Gharib H, Goellner JR, van Heerden JA. Metastasis to the thyroid gland. A report of 43 cases. Cancer. 1997;79(3):574–8.CrossRefPubMed Nakhjavani MK, Gharib H, Goellner JR, van Heerden JA. Metastasis to the thyroid gland. A report of 43 cases. Cancer. 1997;79(3):574–8.CrossRefPubMed
23.
Zurück zum Zitat Wada N, Hirakawa S, Rino Y, et al. Solitary metachronous metastasis to the thyroid from renal clear cell carcinoma 19 years after nephrectomy: report of a case. Surg Today. 2005;35(6):483–7.CrossRefPubMed Wada N, Hirakawa S, Rino Y, et al. Solitary metachronous metastasis to the thyroid from renal clear cell carcinoma 19 years after nephrectomy: report of a case. Surg Today. 2005;35(6):483–7.CrossRefPubMed
24.
Zurück zum Zitat Iesalnieks I, Trupka A, Raab M, et al. Renal cell carcinoma metastases to the thyroid gland-8 cases reported. Thyroid. 2007;17(1):49–52.CrossRefPubMed Iesalnieks I, Trupka A, Raab M, et al. Renal cell carcinoma metastases to the thyroid gland-8 cases reported. Thyroid. 2007;17(1):49–52.CrossRefPubMed
25.
Zurück zum Zitat Hadjadj S, Geoffrois L, Aubert V, Weryha G, Leclere J. Thyroid metastases from cancer of the kidney. Two cases. Presse Med. 1995;24(30):1386–8.PubMed Hadjadj S, Geoffrois L, Aubert V, Weryha G, Leclere J. Thyroid metastases from cancer of the kidney. Two cases. Presse Med. 1995;24(30):1386–8.PubMed
26.
Zurück zum Zitat Watts NB. Carcinoma metastatic to the thyroid: prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci. 1987;293(1):13–7.CrossRefPubMed Watts NB. Carcinoma metastatic to the thyroid: prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci. 1987;293(1):13–7.CrossRefPubMed
27.
Zurück zum Zitat Schroder S, Bocker W. Clear-cell carcinomas of thyroid gland: a clinicopathological study of 13 cases. Histopathology. 1986;10(1):75–89.CrossRefPubMed Schroder S, Bocker W. Clear-cell carcinomas of thyroid gland: a clinicopathological study of 13 cases. Histopathology. 1986;10(1):75–89.CrossRefPubMed
Metadaten
Titel
Tumor-to-Tumor Metastasis: Renal Cell Carcinoma Metastatic to Papillary Carcinoma of Thyroid—Report of a Case and Review of the Literature
verfasst von
Olga L. Bohn
Luis E. De las Casas
Marino E. Leon
Publikationsdatum
01.12.2009
Verlag
Humana Press Inc
Erschienen in
Head and Neck Pathology / Ausgabe 4/2009
Elektronische ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-009-0147-9

Weitere Artikel der Ausgabe 4/2009

Head and Neck Pathology 4/2009 Zur Ausgabe

63rd Annual Meeting of the American Academy of Oral and Maxillofacial Pathology

Clinico-Pathologic Conference: Case 4

63rd Annual Meeting of the American Academy of Oral and Maxillofacial Pathology

Clinico-Pathologic Conference: Case 6

63rd Annual Meeting of the American Academy of Oral and Maxillofacial Pathology

Clinico-Pathologic Conference: Case 3

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Open Access Biomarker Leitthema

Um auch an kleinen Gewebeproben zuverlässige und reproduzierbare Ergebnisse zu gewährleisten ist eine strenge Qualitätskontrolle in jedem Schritt des Arbeitsablaufs erforderlich. Eine nicht ordnungsgemäße Prüfung oder Behandlung des …

Vergleichende Pathologie in der onkologischen Forschung

Pathologie Leitthema

Die vergleichende experimentelle Pathologie („comparative experimental pathology“) ist ein Fachbereich an der Schnittstelle von Human- und Veterinärmedizin. Sie widmet sich der vergleichenden Erforschung von Gemeinsamkeiten und Unterschieden von …

Gastrointestinale Stromatumoren

Open Access GIST CME-Artikel

Gastrointestinale Stromatumoren (GIST) stellen seit über 20 Jahren ein Paradigma für die zielgerichtete Therapie mit Tyrosinkinaseinhibitoren dar. Eine elementare Voraussetzung für eine mögliche neoadjuvante oder adjuvante Behandlung bei …

Personalisierte Medizin in der Onkologie

Aufgrund des erheblichen technologischen Fortschritts in der molekularen und genetischen Diagnostik sowie zunehmender Erkenntnisse über die molekulare Pathogenese von Krankheiten hat in den letzten zwei Jahrzehnten ein grundlegender …