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01.03.2012 | Case Report

Ganglioneuroblastic Transformation in Olfactory Neuroblastoma

verfasst von: Timothy Bates, Daniel Du Plessis, Tuomo Polvikoski, Philip Sloan, Andrew McQueen, David Meikle, Charles Kelly, Max Robinson

Erschienen in: Head and Neck Pathology | Ausgabe 1/2012

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Abstract

Ganglioneuroblastic transformation in olfactory neuroblastoma (ONB) is an exceptionally rare phenomenon. We document the case of a patient with a poorly differentiated sinonasal malignancy that recurred following treatment with chemoradiotherapy and showed ganglioneuroblastic transformation. Although the index tumour showed neuroendocrine differentiation, it did not have the typical clinico-pathological features associated with ONB. We highlight the diagnostic difficulties in establishing an accurate diagnosis for undifferentiated sinonasal tumours and present evidence that the index tumour was an ONB. The current report is only the third case of ONB showing complete ganglioneuroblastic transformation.

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Titel: Ganglioneuroblastic Transformation in Olfactory Neuroblastoma
verfasst von: Timothy Bates
Daniel Du Plessis
Tuomo Polvikoski
Philip Sloan
Andrew McQueen
David Meikle
Charles Kelly
Max Robinson
Publikationsdatum: 01.03.2012
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2012
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-011-0293-8

Springer Medizin

Ganglioneuroblastic Transformation in Olfactory Neuroblastoma

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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