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Journal of Parasitic Diseases

Erschienen in:

23.10.2018 | Original Article

Seroepidemiological evaluation of Toxoplasma gondii immunity among the general population in southwest of Iran

verfasst von: Shahrzad Soltani, Masoud Foroutan, Hamed Afshari, Maryam Hezarian, Mehdi Sagha Kahvaz

Erschienen in: Journal of Parasitic Diseases | Ausgabe 4/2018

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Abstract

Toxoplasmosis is a cosmopolitan zoonotic infection, caused by a unicellular protozoan parasite known as Toxoplasma gondii (T. gondii) that belongs to the phylum Apicomplexa. The present investigation was aimed to evaluate the seroprevalence of T. gondii infection in the general population of Abadan city. In this cross-sectional study, a total of 496 subjects were participated. Anti-T. gondii IgG and IgM antibodies were tested using commercially available enzyme-linked immunosorbent assay (ELISA). Moreover, a structured questionnaire was completed for each person. Out of 496 subjects, 188 (37.9%) and 30 (6.05%) samples were seropositive for IgG and IgM, respectively. The more seroprevalence was found during spring season, among female subjects, in rural inhabitants, in persons with the education level of diploma or lower, from the subjects with a history of contact with cat, in individuals who consumed raw/undercooked meat, and amongst who drink unpurified water. The results showed that inhabitants of tropical areas, may be moderately exposed to T. gondii. Increase of knowledge of people about toxoplasmosis, certainly affects in reduction of the infection.

Belluco S, Mancin M, Conficoni D, Simonato G, Pietrobelli M, Ricci A (2016) Investigating the determinants of Toxoplasma gondii prevalence in meat: a systematic review and meta-regression. PLoS ONE 11(4):e0153856. https://doi.org/10.1371/journal.pone.0153856 CrossRefPubMedPubMedCentral

Cong W et al (2015) Toxoplasma gondii infection in pregnant women: a seroprevalence and case-control study in Eastern China. Biomed Res Int 2015:170278. https://doi.org/10.1155/2015/170278 CrossRefPubMedPubMedCentral

Daryani A et al (2014) Seroprevalence of Toxoplasma gondii in the Iranian general population: a systematic review and meta-analysis. Acta Trop 137:94–185. https://doi.org/10.1016/j.actatropica.2014.05.015 CrossRef

Dubey JP (2008) The history of Toxoplasma gondii—the first 100 years. J Eukaryot Microbiol 55(6):75–467. https://doi.org/10.1111/j.1550-7408.2008.00345.x CrossRef

Fallahi S, Rostami A, Birjandi M, Zebardast N, Kheirandish F, Spotin A (2017) Parkinson’s disease and Toxoplasma gondii infection: sero-molecular assess the possible link among patients. Acta Trop 173:97–101. https://doi.org/10.1016/j.actatropica.2017.06.002 CrossRefPubMed

Fallahi S, Rostami A, Nourollahpour Shiadeh M, Behniafar H, Paktinat S (2018) An updated literature review on maternal-fetal and reproductive disorders of Toxoplasma gondii infection. J Gynecol Obstet Hum Reprod 47(3):133–140. https://doi.org/10.1016/j.jogoh.2017.12.003 CrossRefPubMed

Fatollahzadeh M et al (2016) Study of anti-Toxoplasma IgG and IgM seropositivity among subjects referred to the central laboratory in Tabriz, Iran, 2013-2014. Avicenna J Clin Microbiol Infect 3(3):e35975. https://doi.org/10.17795/ajcmi-35975 CrossRef

Foroutan M, Ghaffarifar F (2018) Calcium-dependent protein kinases are potential targets for Toxoplasma gondii vaccine. Clin Exp Vaccine Res 7(1):24–36. https://doi.org/10.7774/cevr.2018.7.1.24 CrossRefPubMedPubMedCentral

Foroutan M, Majidiani H (2018) Toxoplasma gondii: are there any implications for routine blood screening? Int J Infect 5(1):e62886. https://doi.org/10.5812/iji.62886 CrossRef

Foroutan M et al (2018a) Rolling up the pieces of a puzzle: a systematic review and meta-analysis of the prevalence of toxoplasmosis in Iran. Alex J Med 54(3):189–196. https://doi.org/10.1016/j.ajme.2017.06.003 CrossRef

Foroutan M, Ghaffarifar F, Sharifi Z, Dalimi A, Pirestani M (2018b) Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii. Infect Genet Evol 62:193–204. https://doi.org/10.1016/j.meegid.2018.04.033 CrossRefPubMed

Foroutan M et al (2018c) A systematic review and meta-analysis of the prevalence of toxoplasmosis in hemodialysis patients in Iran. Epidemiol Health 40:e2018016. https://doi.org/10.4178/epih.e2018016 CrossRefPubMedPubMedCentral

Foroutan M, Zaki L, Ghaffarifar F (2018d) Recent progress in microneme-based vaccines development against Toxoplasma gondii. Clin Exp Vaccine Res 7(2):93–103. https://doi.org/10.7774/cevr.2018.7.2.93 CrossRefPubMedPubMedCentral

Foroutan-Rad M, Khademvatan S, Majidiani H, Aryamand S, Rahim F, Malehi AS (2016a) Seroprevalence of Toxoplasma gondii in the Iranian pregnant women: a systematic review and meta-analysis. Acta Trop 158:160–169. https://doi.org/10.1016/j.actatropica.2016.03.003 CrossRefPubMed

Foroutan-Rad M et al (2016b) Toxoplasmosis in blood donors: a systematic review and meta-analysis. Transfus Med Rev 30(3):22–116. https://doi.org/10.1016/j.tmrv.2016.03.002 CrossRef

Gebremedhin EZ, Tadesse G (2015) A meta-analysis of the prevalence of Toxoplasma gondii in animals and humans in Ethiopia. Parasit Vectors 8(1):291. https://doi.org/10.1186/s13071-015-0901-7 CrossRefPubMedPubMedCentral

Ghasemian M, Maraghi S, Saki J, Pedram M (2007) Determination of antibodies (IgG, IgM) against Toxoplasma gondii in patients with cancer. Iran J Parasitol 2(4):1–6

Keshavarz H, Nateghpour M, Zibaei M (1998) Seroepidemiologic survey of toxoplasmosis in Karaj district. Iran J Public Health 27(3–4):73–82

Khademvatan S et al (2017) Toxoplasmosis in rodents: a systematic review and meta-analysis in Iran. J Infect Public Health 10(5):487–493. https://doi.org/10.1016/j.jiph.2017.01.021 CrossRefPubMed

Majidiani H, Dalvand S, Daryani A, Galvan-Ramirez ML, Foroutan-Rad M (2016) Is chronic toxoplasmosis a risk factor for diabetes mellitus? A systematic review and meta-analysis of case-control studies. Braz J Infect Dis 20(6):605–609. https://doi.org/10.1016/j.bjid.2016.09.002 CrossRefPubMed

Manouchehri Naeini K, Mortazaei S, Zebardast N, Kheiri S (2012) Seroprevalence and some of risk factors affecting Toxoplasma infection in Chaharmahal va Bakhtiyari province, Iran. J Share Univ Med Sci 13(6):8–18 (In Persian)

Mansouri F, Hatami H, Mahdavian B, Hashemian AH (2003) Epidemiology of toxoplasmosis in Kermanshah province. J Kermanshah Univ Med Sci 7(2):12–19 (In Persian)

Mansouri A et al (2017) Epidemiology of Toxoplasma gondii among blood donors in Iran: a systematic review and meta-analysis. Transfus Apher Sci 56(3):404–409. https://doi.org/10.1016/j.transci.2017.03.011 CrossRefPubMed

Maraghi S, YadYad M, Sheikhi M, LatifiS M (2013a) Frequency of anti-Toxoplasma antibodies in midwifery and nursing students of Abadan Islamic Azad University students in 2011. Armaghane Dan 18(4):327–336 (In Persian)

Maraghi S, Yadyad MJ, Sheikhi M, Shamakhteh F, Latifi SM (2013b) Study the anti-Toxoplasma antibodies (IgG and IgM) in hemodialysis patients of Abadan and Khoramshahr cities Southwest Iran in 2011 using ELISA. Jundishapur J Microbiol 6(7):e7113. https://doi.org/10.5812/jjm.7113 CrossRef

Mostafavi SN, Ataei B, Nokhodian Z, Yaran M, Babak A (2011) Seroepidemiology of Toxoplasma gondii infection in Isfahan province, central Iran: a population based study. J Res Med Sci 16(4):496–501 (In Persian) PubMedPubMedCentral

Razavi S, Esnaashari H, Gheysari H (2003) Seroepidemiological survey of toxoplasmosis by IFA technique in the students of Faculty of Veterinary Medicine, University of Shiraz. J Vet Res 58(2):163–167

Rostami A et al (2016) Seroprevalence and risk factors associated with Toxoplasma gondii infection among rural communities in Northern Iran. Rev Inst Med Trop Sao Paulo 58:70. https://doi.org/10.1590/S1678-9946201658070 CrossRefPubMedPubMedCentral

Rostami A, Karanis P, Fallahi S (2018) Advances in serological, imaging techniques and molecular diagnosis of Toxoplasma gondii infection. Infection 46(3):303–315. https://doi.org/10.1007/s15010-017-1111-3 CrossRefPubMed

Saki J, Khademvatan S, Soltani S, Shahbazian H (2013) Detection of toxoplasmosis in patients with end-stage renal disease by enzyme-linked immunosorbent assay and polymerase chain reaction methods. Parasitol Res 112(1):8–163. https://doi.org/10.1007/s00436-012-3120-6 CrossRef

Saki J, Mohammadpour N, Moramezi F, Khademvatan S (2015) Seroprevalence of Toxoplasma gondii in women who have aborted in comparison with the women with normal delivery in Ahvaz, southwest of Iran. Sci World J 2015:764369. https://doi.org/10.1155/2015/764369 CrossRef

Saki J, Shafieenia S, Foroutan-Rad M (2016) Seroprevalence of toxoplasmosis in diabetic pregnant women in southwestern of Iran. J Parasit Dis 40(4):1586–1589. https://doi.org/10.1007/s12639-015-0735-4 CrossRefPubMedPubMedCentral

Saki J, Tavakoli S, Pedram M (2017) Seroprevalence and molecular evaluation of toxoplasmosis in children with cancer in Khuzestan province, Southwest of Iran. J Parasit Dis 41(4):947–951. https://doi.org/10.1007/s12639-017-0916-4 CrossRefPubMed

Salahi-Moghaddam A, Hafizi A (2009) A serological study on Toxoplasma gondii infection among people in south of Tehran, Iran. Korean J Parasitol 47(1):3–61. https://doi.org/10.3347/kjp.2009.47.1.61 CrossRef

Shahmoradi A, Daryani A, Hajizadeh A (1998) Seroepidemiological survey of toxoplasmosis in individuals referred to Health Center of Roodsar, Gilan. J Shahid Beheshti Univ Med Sci 4:7–12 (In Persian)

Soltan Mohammad Zadeh M, Keshavarz H, Mohebali M, Holakouie Naieni K, Arshi S (2003) Seroepidemiologic study of human Toxoplasma infection in residents of Meshkin-Shahr. J Sch Public Health Inst Public Health Res 1(4):57–72 (In Persian)

Soltani S, Khademvatan S, Saki J, Shahbazian H (2013) Detection of toxoplasmosis in renal transplant recipients by ELISA and PCR methods in Ahvaz, Southwest of Iran. Jundishapur J Microbiol 6(9):e7642. https://doi.org/10.5812/Jjm.7642 CrossRef

Wang ZD et al (2017) Toxoplasma gondii infection in immunocompromised patients: a systematic review and meta-analysis. Front Microbiol 8:389. https://doi.org/10.3389/fmicb.2017.00389 CrossRefPubMedPubMedCentral

Wang T, Han Y, Pan Z, Wang H, Yuan M, Lin H (2018) Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis. Parasite 25:36. https://doi.org/10.1051/parasite/2018037 CrossRefPubMedPubMedCentral

Yad Yad MJ, Jomehzadeh N, Jafar Sameri M, Noorshahi N (2014) Seroprevalence of anti-Toxoplasma gondii antibodies among pregnant woman in South Khuzestan, Iran. Jundishapur J Microbiol 7(5):e9998. https://doi.org/10.5812/jjm.9998 CrossRefPubMedPubMedCentral

Yousefi E, Foroutan M, Salehi R, Khademvatan S (2017) Detection of acute and chronic toxoplasmosis amongst multi-transfused thalassemia patients in southwest of Iran. J Acute Dis 6(3):120–125. https://doi.org/10.12980/jad.6.2017JADWEB-2017-0008 CrossRef

Titel: Seroepidemiological evaluation of Toxoplasma gondii immunity among the general population in southwest of Iran
verfasst von: Shahrzad Soltani
Masoud Foroutan
Hamed Afshari
Maryam Hezarian
Mehdi Sagha Kahvaz
Publikationsdatum: 23.10.2018
Verlag: Springer India
Erschienen in: Journal of Parasitic Diseases / Ausgabe 4/2018
Print ISSN: 0971-7196
Elektronische ISSN: 0975-0703
DOI: https://doi.org/10.1007/s12639-018-1047-2

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