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Erschienen in: Current Nutrition Reports 3/2014

01.09.2014 | Prenatal, Neonatal, and Maternal Nutrition (DK Tobias and MF Hivert, Section Editors)

Prenatal Dietary Determinants of Asthma and Related Allergic Disorders in Childhood

verfasst von: Ekaterina Maslova, Susanne Hansen

Erschienen in: Current Nutrition Reports | Ausgabe 3/2014

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Abstract

The rise in asthma and allergic disease in recent decades, with accompanying morbidity and healthcare costs, has placed these conditions on the forefront of public health challenges. Allergic disease manifests itself shortly after birth, suggesting that disease development may commence already during fetal life. The early origins of these conditions and the concomitant changes in dietary habits have led to the formulation of several hypotheses relating dietary intake during pregnancy to deviant developmental adaptations in the fetal immune system and lung growth. These hypotheses are further supported by the demonstrated involvement of many nutrients, including fatty acids, antioxidants, and food allergens, in immune system function and maturation. Understanding the potential in utero influence of these nutrients on child allergic disease risk will provide a unique window of opportunity for early prevention by guiding women and their children to better health.
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Zurück zum Zitat Noteboom ML, Mommers M, Jansen EHJM, Penders J, Thijs C. Maternal fatty acid status in pregnancy and childhood atopic manifestations: KOALA Birth Cohort Study. Clin Exp Allergy. 2011;41:407–16. Noteboom ML, Mommers M, Jansen EHJM, Penders J, Thijs C. Maternal fatty acid status in pregnancy and childhood atopic manifestations: KOALA Birth Cohort Study. Clin Exp Allergy. 2011;41:407–16.
57.•
Zurück zum Zitat Pike KC, Calder PC, Inskip HM, Robinson SM, Roberts GC, Cooper C. Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years. Clin Dev Immunol. 2012;2012:474613. This detailed study of 865 mother-child pairs examined maternal levels of n-3 and n-6 PUFAs during pregnancy in relation to wheeze patterns, atopy, airway inflammation, and lung function during the first 6 years of life. The study found both n-3 and n-6 PUFAs to be protective of allergic conditions. Interestingly, the study also implicated the ratio between the substrates (ALA and LA) and the desaturated products in atopy and wheeze development, a finding that awaits replication in other studies. Pike KC, Calder PC, Inskip HM, Robinson SM, Roberts GC, Cooper C. Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years. Clin Dev Immunol. 2012;2012:474613. This detailed study of 865 mother-child pairs examined maternal levels of n-3 and n-6 PUFAs during pregnancy in relation to wheeze patterns, atopy, airway inflammation, and lung function during the first 6 years of life. The study found both n-3 and n-6 PUFAs to be protective of allergic conditions. Interestingly, the study also implicated the ratio between the substrates (ALA and LA) and the desaturated products in atopy and wheeze development, a finding that awaits replication in other studies.
58.
Zurück zum Zitat Standl M, Demmelmair H, Koletzko B, Heinrich J. Cord blood LC-PUFA composition and allergic diseases during the first 10 yr. Pediatr Allergy Immunol: Results from the LISAplus study; 2014. Standl M, Demmelmair H, Koletzko B, Heinrich J. Cord blood LC-PUFA composition and allergic diseases during the first 10 yr. Pediatr Allergy Immunol: Results from the LISAplus study; 2014.
59.
Zurück zum Zitat Nwaru BI, Erkkola M, Lumia M, Kronberg-Kippila C, Ahonen S, Kaila M, et al. Maternal intake of fatty acids during pregnancy and allergies in the offspring. Br J Nutr. 2012;108(4):720–32.PubMed Nwaru BI, Erkkola M, Lumia M, Kronberg-Kippila C, Ahonen S, Kaila M, et al. Maternal intake of fatty acids during pregnancy and allergies in the offspring. Br J Nutr. 2012;108(4):720–32.PubMed
60.
Zurück zum Zitat Oddy WH, de Klerk NH, Kendall GE, Mihrshahi S, Peat JK. Ratio of omega-6 to omega-3 fatty acids and childhood asthma. J Asthma. 2004;41(3):319–26.PubMed Oddy WH, de Klerk NH, Kendall GE, Mihrshahi S, Peat JK. Ratio of omega-6 to omega-3 fatty acids and childhood asthma. J Asthma. 2004;41(3):319–26.PubMed
61.
Zurück zum Zitat Covaci A, Jorens P, Jacquemyn Y, Schepens P. Distribution of PCBs and organochlorine pesticides in umbilical cord and maternal serum. Sci Total Environ. 2002;298(1–3):45–53.PubMed Covaci A, Jorens P, Jacquemyn Y, Schepens P. Distribution of PCBs and organochlorine pesticides in umbilical cord and maternal serum. Sci Total Environ. 2002;298(1–3):45–53.PubMed
62.
Zurück zum Zitat Park JS, Bergman A, Linderholm L, Athanasiadou M, Kocan A, Petrik J, et al. Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia. Chemosphere. 2008;70(9):1676–84.PubMedCentralPubMed Park JS, Bergman A, Linderholm L, Athanasiadou M, Kocan A, Petrik J, et al. Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia. Chemosphere. 2008;70(9):1676–84.PubMedCentralPubMed
63.
Zurück zum Zitat Gascon M, Vrijheid M, Martinez D, Ballester F, Basterrechea M, Blarduni E, et al. Pre-natal exposure to dichlorodiphenyldichloroethylene and infant lower respiratory tract infections and wheeze. Eur Respir J. 2012;39(5):1188–96.PubMed Gascon M, Vrijheid M, Martinez D, Ballester F, Basterrechea M, Blarduni E, et al. Pre-natal exposure to dichlorodiphenyldichloroethylene and infant lower respiratory tract infections and wheeze. Eur Respir J. 2012;39(5):1188–96.PubMed
64.
Zurück zum Zitat Grandjean P, Poulsen LK, Heilmann C, Steuerwald U, Weihe P. Allergy and sensitization during childhood associated with prenatal and lactational exposure to marine pollutants. Environ Health Perspect. 2010;118(10):1429–33.PubMedCentralPubMed Grandjean P, Poulsen LK, Heilmann C, Steuerwald U, Weihe P. Allergy and sensitization during childhood associated with prenatal and lactational exposure to marine pollutants. Environ Health Perspect. 2010;118(10):1429–33.PubMedCentralPubMed
65.
Zurück zum Zitat Hansen S, Strom M, Olsen SF, Maslova E, Rantakokko P, Kiviranta H, et al. Maternal concentrations of persistent organochlorine pollutants and the risk of asthma in offspring: results from a prospective cohort with 20 years of follow-up. Environ Health Perspect. 2014;122(1):93–9.PubMedCentralPubMed Hansen S, Strom M, Olsen SF, Maslova E, Rantakokko P, Kiviranta H, et al. Maternal concentrations of persistent organochlorine pollutants and the risk of asthma in offspring: results from a prospective cohort with 20 years of follow-up. Environ Health Perspect. 2014;122(1):93–9.PubMedCentralPubMed
66.
Zurück zum Zitat Stolevik SB, Nygaard UC, Namork E, Haugen M, Kvalem HE, Meltzer HM, et al. Prenatal exposure to polychlorinated biphenyls and dioxins is associated with increased risk of wheeze and infections in infants. Food Chem Toxicol. 2011;49(8):1843–8.PubMed Stolevik SB, Nygaard UC, Namork E, Haugen M, Kvalem HE, Meltzer HM, et al. Prenatal exposure to polychlorinated biphenyls and dioxins is associated with increased risk of wheeze and infections in infants. Food Chem Toxicol. 2011;49(8):1843–8.PubMed
67.
Zurück zum Zitat Stolevik SB, Nygaard UC, Namork E, Haugen M, Meltzer HM, Alexander J, et al. Prenatal exposure to polychlorinated biphenyls and dioxins from the maternal diet may be associated with immunosuppressive effects that persist into early childhood. Food Chem Toxicol. 2013;51:165–72.PubMed Stolevik SB, Nygaard UC, Namork E, Haugen M, Meltzer HM, Alexander J, et al. Prenatal exposure to polychlorinated biphenyls and dioxins from the maternal diet may be associated with immunosuppressive effects that persist into early childhood. Food Chem Toxicol. 2013;51:165–72.PubMed
68.
Zurück zum Zitat Sunyer J, Torrent M, Garcia-Esteban R, Ribas-Fito N, Carrizo D, Romieu I, et al. Early exposure to dichlorodiphenyldichloroethylene, breastfeeding and asthma at age six. Clin Exp Allergy. 2006;36(10):1236–41.PubMed Sunyer J, Torrent M, Garcia-Esteban R, Ribas-Fito N, Carrizo D, Romieu I, et al. Early exposure to dichlorodiphenyldichloroethylene, breastfeeding and asthma at age six. Clin Exp Allergy. 2006;36(10):1236–41.PubMed
69.
Zurück zum Zitat Sunyer J, Torrent M, Munoz-Ortiz L, Ribas-Fito N, Carrizo D, Grimalt J, et al. Prenatal dichlorodiphenyldichloroethylene (DDE) and asthma in children. Environ Health Perspect. 2005;113(12):1787–90.PubMedCentralPubMed Sunyer J, Torrent M, Munoz-Ortiz L, Ribas-Fito N, Carrizo D, Grimalt J, et al. Prenatal dichlorodiphenyldichloroethylene (DDE) and asthma in children. Environ Health Perspect. 2005;113(12):1787–90.PubMedCentralPubMed
70.
Zurück zum Zitat ten Tusscher GW, de Weerdt J, Roos CM, Griffioen RW, De Jongh FH, Westra M, et al. Decreased lung function associated with perinatal exposure to Dutch background levels of dioxins. Acta Paediatr. 2001;90(11):1292–8.PubMed ten Tusscher GW, de Weerdt J, Roos CM, Griffioen RW, De Jongh FH, Westra M, et al. Decreased lung function associated with perinatal exposure to Dutch background levels of dioxins. Acta Paediatr. 2001;90(11):1292–8.PubMed
71.
Zurück zum Zitat Miyake Y, Tanaka K, Yasutake A, Sasaki S, Hirota Y. Lack of association of mercury with risk of wheeze and eczema in Japanese children: the Osaka Maternal and Child Health Study. Environ Res. 2011;111(8):1180–4.PubMed Miyake Y, Tanaka K, Yasutake A, Sasaki S, Hirota Y. Lack of association of mercury with risk of wheeze and eczema in Japanese children: the Osaka Maternal and Child Health Study. Environ Res. 2011;111(8):1180–4.PubMed
72.
Zurück zum Zitat Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002;56(8):365–79.PubMed Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed Pharmacother. 2002;56(8):365–79.PubMed
73.
Zurück zum Zitat Calvani M, Alessandri C, Sopo S, Panetta V, Pingitore G, Tripodi S, et al. Consumption of fish, butter and margarine during pregnancy and development of allergic sensitizations in the offspring: role of maternal atopy. Pediatr Allergy Immunol. 2006;17(2):94–102.PubMed Calvani M, Alessandri C, Sopo S, Panetta V, Pingitore G, Tripodi S, et al. Consumption of fish, butter and margarine during pregnancy and development of allergic sensitizations in the offspring: role of maternal atopy. Pediatr Allergy Immunol. 2006;17(2):94–102.PubMed
74.
Zurück zum Zitat Butt MS, Sultan MT. Levels of trans fats in diets consumed in developing economies. J AOAC Int. 2009;92(5):1277–83.PubMed Butt MS, Sultan MT. Levels of trans fats in diets consumed in developing economies. J AOAC Int. 2009;92(5):1277–83.PubMed
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Zurück zum Zitat L'Abbe MR, Stender S, Skeaff CM, Ghafoorunissa, Tavella M. Approaches to removing trans fats from the food supply in industrialized and developing countries. Eur J Clin Nutr. 2009;63:S50–S67 L'Abbe MR, Stender S, Skeaff CM, Ghafoorunissa, Tavella M. Approaches to removing trans fats from the food supply in industrialized and developing countries. Eur J Clin Nutr. 2009;63:S50–S67
76.
Zurück zum Zitat Chatzi L, Garcia R, Roumeliotaki T, Basterrechea M, Begiristain H, Iniguez C, et al. Mediterranean diet adherence during pregnancy and risk of wheeze and eczema in the first year of life: INMA (Spain) and RHEA (Greece) mother-child cohort studies. Br J Nutr. 2013;110(11):2058–68.PubMed Chatzi L, Garcia R, Roumeliotaki T, Basterrechea M, Begiristain H, Iniguez C, et al. Mediterranean diet adherence during pregnancy and risk of wheeze and eczema in the first year of life: INMA (Spain) and RHEA (Greece) mother-child cohort studies. Br J Nutr. 2013;110(11):2058–68.PubMed
77.
Zurück zum Zitat Erkkola M, Nwaru BI, Kaila M, Kronberg-Kippila C, Ilonen J, Simell O, et al. Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. Pediatr Allergy Immunol. 2012;23(2):186–94.PubMed Erkkola M, Nwaru BI, Kaila M, Kronberg-Kippila C, Ilonen J, Simell O, et al. Risk of asthma and allergic outcomes in the offspring in relation to maternal food consumption during pregnancy: a Finnish birth cohort study. Pediatr Allergy Immunol. 2012;23(2):186–94.PubMed
78.
Zurück zum Zitat Maslova E, Halldorsson TI, Strøm M, Olsen SF. Low-fat yoghurt intake in pregnancy associated with increased child asthma and allergic rhinitis risk: a prospective cohort study. Journal of Nutritional Science. 2012;1:null-null. Maslova E, Halldorsson TI, Strøm M, Olsen SF. Low-fat yoghurt intake in pregnancy associated with increased child asthma and allergic rhinitis risk: a prospective cohort study. Journal of Nutritional Science. 2012;1:null-null.
79.
Zurück zum Zitat Miyake Y, Sasaki S, Tanaka K, Hirota Y. Dairy food, calcium, and vitamin D intake in pregnancy and wheeze and eczema in infants. ERJ Express. 2009. Miyake Y, Sasaki S, Tanaka K, Hirota Y. Dairy food, calcium, and vitamin D intake in pregnancy and wheeze and eczema in infants. ERJ Express. 2009.
80.•
Zurück zum Zitat Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Jr., et al. Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children. J Allergy Clin Immunol. 2014. Using data from 1,277 mother-child dyads enrolled in a U.S. cohort, this study examined peanut consumption along with other allergenic foods in pregnancy in relation to asthma and related allergic conditions in mid-childhood. There were no associations between maternal peanut intake and child asthma, allergic rhinitis, and allergic dermatitis. However, peanut intake in first, but not second, trimester reduced the odds of peanut allergic reaction in childhood by 47 % (95 % CI: 6–70 %). Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Jr., et al. Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children. J Allergy Clin Immunol. 2014. Using data from 1,277 mother-child dyads enrolled in a U.S. cohort, this study examined peanut consumption along with other allergenic foods in pregnancy in relation to asthma and related allergic conditions in mid-childhood. There were no associations between maternal peanut intake and child asthma, allergic rhinitis, and allergic dermatitis. However, peanut intake in first, but not second, trimester reduced the odds of peanut allergic reaction in childhood by 47 % (95 % CI: 6–70 %).
81.•
Zurück zum Zitat Thijs C, Muller A, Rist L, Kummeling I, Snijders BE, Huber M. Fatty acids in breast milk and development of atopic eczema and allergic sensitisation in infancy. Allergy. 2011;66(1):58–67. The second study to suggest that ruminant fatty acids, including conjugated linoleic acid, in breast milk reduces early life atopic dermatitis and atopy. While these findings are preliminary and await replication from studies with exposure measures during pregnancy, they are nonetheless suggestive of the role of other fatty acids in allergic disease development.PubMed Thijs C, Muller A, Rist L, Kummeling I, Snijders BE, Huber M. Fatty acids in breast milk and development of atopic eczema and allergic sensitisation in infancy. Allergy. 2011;66(1):58–67. The second study to suggest that ruminant fatty acids, including conjugated linoleic acid, in breast milk reduces early life atopic dermatitis and atopy. While these findings are preliminary and await replication from studies with exposure measures during pregnancy, they are nonetheless suggestive of the role of other fatty acids in allergic disease development.PubMed
82.
Zurück zum Zitat Jaudszus A, Krokowski M, Möckel P, Darcan Y, Avagyan A, Matricardi P, et al. Cis-9, trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J Nutr. 2008;138(7):1336–42.PubMed Jaudszus A, Krokowski M, Möckel P, Darcan Y, Avagyan A, Matricardi P, et al. Cis-9, trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J Nutr. 2008;138(7):1336–42.PubMed
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Zurück zum Zitat Kanwar R, MacGibbon A, Black P, Kanwar J, Rowan A, Vale M, et al. Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic airway disease in mice. Clin Exp Allergy. 2007;38:208–18.PubMed Kanwar R, MacGibbon A, Black P, Kanwar J, Rowan A, Vale M, et al. Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic airway disease in mice. Clin Exp Allergy. 2007;38:208–18.PubMed
84.
Zurück zum Zitat Whigham LD, Cook EB, Stahl JL, Saban R, Bjorling DE, Pariza MW, et al. CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae. Am J Physiol Regul Integr Comp Physiol. 2001;280(3):R908–12.PubMed Whigham LD, Cook EB, Stahl JL, Saban R, Bjorling DE, Pariza MW, et al. CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae. Am J Physiol Regul Integr Comp Physiol. 2001;280(3):R908–12.PubMed
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Zurück zum Zitat Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81(3):353–73.PubMed Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006;81(3):353–73.PubMed
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Zurück zum Zitat Lamberg-Allardt C. Vitamin D, in foods and as supplements. Prog Biophys Mol Biol. 2006;92(1):33–8.PubMed Lamberg-Allardt C. Vitamin D, in foods and as supplements. Prog Biophys Mol Biol. 2006;92(1):33–8.PubMed
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Zurück zum Zitat Fleischman AR, Rosen JF, Cole J, Smith CM, Deluca HF. Maternal and fetal serum 1,25-dihydroxyvitamin D levels at term. J Pediatr. 1980;97(4):640–2.PubMed Fleischman AR, Rosen JF, Cole J, Smith CM, Deluca HF. Maternal and fetal serum 1,25-dihydroxyvitamin D levels at term. J Pediatr. 1980;97(4):640–2.PubMed
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Zurück zum Zitat Thomas SD, Fudge AN, Whiting M, Coates PS. The correlation between third-trimester maternal and newborn-serum 25-hydroxy-vitamin D in a selected South Australian group of newborn samples. BMJ Open. 2011;1(2):e000236.PubMedCentralPubMed Thomas SD, Fudge AN, Whiting M, Coates PS. The correlation between third-trimester maternal and newborn-serum 25-hydroxy-vitamin D in a selected South Australian group of newborn samples. BMJ Open. 2011;1(2):e000236.PubMedCentralPubMed
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Zurück zum Zitat Litonjua A. Dietary factors and the development of asthma. Immunol Allergy Clin North Am. 2008;28(3):603–29. ix.PubMedCentralPubMed Litonjua A. Dietary factors and the development of asthma. Immunol Allergy Clin North Am. 2008;28(3):603–29. ix.PubMedCentralPubMed
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Zurück zum Zitat Wjst M. Is vitamin D supplementation responsible for the allergy pandemic? Curr Opin Allergy Clin Immunol. 2012;12(3):257–62.PubMed Wjst M. Is vitamin D supplementation responsible for the allergy pandemic? Curr Opin Allergy Clin Immunol. 2012;12(3):257–62.PubMed
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Zurück zum Zitat Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A. 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol. 2001;167(9):4974–80.PubMed Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A. 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol. 2001;167(9):4974–80.PubMed
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Zurück zum Zitat Cantorna MT, Woodward WD, Hayes CE, DeLuca HF. 1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4. J Immunol. 1998;160(11):5314–9.PubMed Cantorna MT, Woodward WD, Hayes CE, DeLuca HF. 1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4. J Immunol. 1998;160(11):5314–9.PubMed
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Zurück zum Zitat Gregori S, Giarratana N, Smiroldo S, Uskokovic M, Adorini L. A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice. Diabetes. 2002;51(5):1367–74.PubMed Gregori S, Giarratana N, Smiroldo S, Uskokovic M, Adorini L. A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice. Diabetes. 2002;51(5):1367–74.PubMed
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Zurück zum Zitat Matheu V, Back O, Mondoc E, Issazadeh-Navikas S. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease. J Allergy Clin Immunol. 2003;112(3):585–92.PubMed Matheu V, Back O, Mondoc E, Issazadeh-Navikas S. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease. J Allergy Clin Immunol. 2003;112(3):585–92.PubMed
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Zurück zum Zitat Pichler J, Gerstmayr M, Szepfalusi Z, Urbanek R, Peterlik M, Willheim M. 1 alpha,25(OH)2D3 inhibits not only Th1 but also Th2 differentiation in human cord blood T cells. Pediatr Res. 2002;52(1):12–8.PubMed Pichler J, Gerstmayr M, Szepfalusi Z, Urbanek R, Peterlik M, Willheim M. 1 alpha,25(OH)2D3 inhibits not only Th1 but also Th2 differentiation in human cord blood T cells. Pediatr Res. 2002;52(1):12–8.PubMed
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Zurück zum Zitat Camargo CJ, Rifas-Shiman S, Litonjua A, Rich-Edwards J, Weiss S, Gold D, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr. 2007;85(3):788–95.PubMed Camargo CJ, Rifas-Shiman S, Litonjua A, Rich-Edwards J, Weiss S, Gold D, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr. 2007;85(3):788–95.PubMed
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Zurück zum Zitat Devereux G, Litonjua A, Turner S, Craig L, McNeill G, Martindale S, et al. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr. 2007;85(3):853–9.PubMed Devereux G, Litonjua A, Turner S, Craig L, McNeill G, Martindale S, et al. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr. 2007;85(3):853–9.PubMed
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Zurück zum Zitat Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippila C, Ahonen S, Nevalainen J, et al. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy. 2009;39(6):875–82.PubMed Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippila C, Ahonen S, Nevalainen J, et al. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy. 2009;39(6):875–82.PubMed
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Zurück zum Zitat Maslova E, Hansen S, Jensen CB, Thorne-Lyman AL, Strom M, Olsen SF. Vitamin D intake in mid-pregnancy and child allergic disease - a prospective study in 44,825 Danish mother-child pairs. BMC Pregnancy Childbirth. 2013;13:199.PubMedCentralPubMed Maslova E, Hansen S, Jensen CB, Thorne-Lyman AL, Strom M, Olsen SF. Vitamin D intake in mid-pregnancy and child allergic disease - a prospective study in 44,825 Danish mother-child pairs. BMC Pregnancy Childbirth. 2013;13:199.PubMedCentralPubMed
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Zurück zum Zitat Cremers E, Thijs C, Penders J, Jansen E, Mommers M. Maternal and child's vitamin D supplement use and vitamin D level in relation to childhood lung function: the KOALA Birth Cohort Study. Thorax. 2011;66(6):474–80.PubMed Cremers E, Thijs C, Penders J, Jansen E, Mommers M. Maternal and child's vitamin D supplement use and vitamin D level in relation to childhood lung function: the KOALA Birth Cohort Study. Thorax. 2011;66(6):474–80.PubMed
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Zurück zum Zitat Camargo Jr CA, Ingham T, Wickens K, Thadhani R, Silvers KM, Epton MJ, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics. 2011;127(1):e180–7.PubMed Camargo Jr CA, Ingham T, Wickens K, Thadhani R, Silvers KM, Epton MJ, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics. 2011;127(1):e180–7.PubMed
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Zurück zum Zitat Magnus MC, Stene LC, Haberg SE, Nafstad P, Stigum H, London SJ, et al. Prospective Study of Maternal Mid-pregnancy 25-hydroxyvitamin D Level and Early Childhood Respiratory Disorders. Paediatr Perinat Epidemiol. 2013;27(6):532–41.PubMed Magnus MC, Stene LC, Haberg SE, Nafstad P, Stigum H, London SJ, et al. Prospective Study of Maternal Mid-pregnancy 25-hydroxyvitamin D Level and Early Childhood Respiratory Disorders. Paediatr Perinat Epidemiol. 2013;27(6):532–41.PubMed
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Zurück zum Zitat Morales E, Romieu I, Guerra S, Ballester F, Rebagliato M, Vioque J, et al. Maternal vitamin D status in pregnancy and risk of lower respiratory tract infections, wheezing, and asthma in offspring. Epidemiology. 2012;23(1):64–71.PubMed Morales E, Romieu I, Guerra S, Ballester F, Rebagliato M, Vioque J, et al. Maternal vitamin D status in pregnancy and risk of lower respiratory tract infections, wheezing, and asthma in offspring. Epidemiology. 2012;23(1):64–71.PubMed
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Zurück zum Zitat Pike KC, Inskip HM, Robinson S, Lucas JS, Cooper C, Harvey NC, et al. Maternal late-pregnancy serum 25-hydroxyvitamin D in relation to childhood wheeze and atopic outcomes. Thorax. 2012;67(11):950–6.PubMedCentralPubMed Pike KC, Inskip HM, Robinson S, Lucas JS, Cooper C, Harvey NC, et al. Maternal late-pregnancy serum 25-hydroxyvitamin D in relation to childhood wheeze and atopic outcomes. Thorax. 2012;67(11):950–6.PubMedCentralPubMed
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Zurück zum Zitat Wills AK, Shaheen SO, Granell R, Henderson AJ, Fraser WD, Lawlor DA. Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function. Clin Exp Allergy. 2013;43(10):1180–8.PubMedCentralPubMed Wills AK, Shaheen SO, Granell R, Henderson AJ, Fraser WD, Lawlor DA. Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function. Clin Exp Allergy. 2013;43(10):1180–8.PubMedCentralPubMed
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Zurück zum Zitat Maslova E, Granstrom C, Hansen S, Petersen SB, Strom M, Willett WC, et al. Peanut and tree nut consumption during pregnancy and allergic disease in children–should mothers decrease their intake? Longitudinal evidence from the Danish National Birth Cohort. J Allergy Clin Immunol. 2012;130(3):724–32. A study of ̴ 45,000 Danish mothers and children measuring peanut and tree nut intake in mid-pregnancy in relation to wheeze, asthma, and allergic rhinitis. Weekly intake of peanuts and tree nuts reduced the odds of asthma in the first 7 years of life with effect estimates varying between 17 % and 35%; tree nuts also reduced the odds of allergic rhinitis (0.80, 95% CI: 0.64, 1.01 ). These results remain to be replicated in other large cohorts Maslova E, Granstrom C, Hansen S, Petersen SB, Strom M, Willett WC, et al. Peanut and tree nut consumption during pregnancy and allergic disease in children–should mothers decrease their intake? Longitudinal evidence from the Danish National Birth Cohort. J Allergy Clin Immunol. 2012;130(3):724–32. A study of ̴ 45,000 Danish mothers and children measuring peanut and tree nut intake in mid-pregnancy in relation to wheeze, asthma, and allergic rhinitis. Weekly intake of peanuts and tree nuts reduced the odds of asthma in the first 7 years of life with effect estimates varying between 17 % and 35%; tree nuts also reduced the odds of allergic rhinitis (0.80, 95% CI: 0.64, 1.01 ). These results remain to be replicated in other large cohorts
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Metadaten
Titel
Prenatal Dietary Determinants of Asthma and Related Allergic Disorders in Childhood
verfasst von
Ekaterina Maslova
Susanne Hansen
Publikationsdatum
01.09.2014
Verlag
Springer US
Erschienen in
Current Nutrition Reports / Ausgabe 3/2014
Elektronische ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-014-0089-z

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