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Erschienen in: Current Addiction Reports 4/2015

01.12.2015 | Transgenerational Considerations in Addictions (LC Mayes and E McCrory, Section Editors)

Gene-Environment Interplay and Substance Use: A Review of Recent Findings

verfasst von: Izabela Milaniak, Bethany Watson, Sara R. Jaffee

Erschienen in: Current Addiction Reports | Ausgabe 4/2015

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Abstract

Substance use problems are chronic and common public health problems. We review recent studies that implicate genetic and environmental factors in their etiology. Although findings are mixed with respect to specific genotypes, some patterns are evident. For example, exposure to peers or parents who engage in high rates of substance use tends to exacerbate genetic diatheses or eliminate the protective effects of certain genotypes. We discuss reasons for mixed findings and highlight the need for translational research to advance understanding of gene function as well as new methods for using genome-wide data in biologically relevant pathways.
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Metadaten
Titel
Gene-Environment Interplay and Substance Use: A Review of Recent Findings
verfasst von
Izabela Milaniak
Bethany Watson
Sara R. Jaffee
Publikationsdatum
01.12.2015
Verlag
Springer International Publishing
Erschienen in
Current Addiction Reports / Ausgabe 4/2015
Elektronische ISSN: 2196-2952
DOI
https://doi.org/10.1007/s40429-015-0069-4

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