Introduction
Materials and methods
Patients
Physical and biochemical findings
Definition of metabolic syndrome
Statistical analyses
Results
Total (n=557) | Fatty pancreas (n=72) | Normal pancreas (n=485) | |
---|---|---|---|
Gender (M:F) | 315:342 | 30:42 | 285:200 |
Age (years)* | 50.8±12.4 | 57.3±12.4 | 20.7±12.8 |
FBG (mg/dl) | 104.7±29.4 | 95.1±20.6 | |
AG (cm)* | 89.8±8.1 | 84.3±9.4 | |
SBP (mm HG)# | 123.2±18.1 | 118.3±16.8 | |
DBP (mm Hg) | 72.7±11.2 | 70.1±11.1 | |
TG (mg/dl)* | 142.5±81.8 | 111.5±70.9 | |
HDL-C (mg/dl) | 46.8±10.4 | 48.8±11.5 | |
Amylase(U/L)* | 93.2±26.6 | 102.3±36.2 | |
HbA1c (%)* | 5.8±0.9 | 5.5±0.7 | |
BMI* | 25.3±2.7 | 23.7±3.5 | |
Girth/Height* | 0.56±0.05 | 0.50±0.06 | |
PLT (×10)* | 263.7±64.7 | 242.3±56.9 |
Metabolic parameters | Fatty pancreas n (%) | Normal pancreas n (%) |
---|---|---|
Abdominal obesity* | 52 (72.2%) | 214 (44.1%) |
TG* | 28 (38.9%) | 93 (19.2%) |
HDL* | 32 (44.4%) | 161 (33.2%) |
HTN* | 24 (33.3%) | 128 (26.4%) |
FBG* | 34 (47.2%) | 95 (19.6%) |
Number of metabolic | Fatty pancreas | Normal pancreas |
---|---|---|
Syndrome parameters | n (%) | n (%) |
0 | 4 (5.6%) | 156 (32.2%) |
1 | 22 (30.6%) | 132 (27.2%) |
2 | 21 (29.2%) | 112 (23.1%) |
3 | 16 (22.2%) | 54 (11.1%) |
4 | 7 (9.7%) | 27 (5.6%) |
5 | 2 (2.8%) | 4 (0.8%) |
Meet ≥ 3 criteria* | 25 (34.7%) | 85 (17.5%) |
Mean number* | 2.1 ± 1.2 | 1.3 ± 1.2 |
Discussion
Association between NAFPD and the parameter of metabolic syndrome
Association between NAFPD and NAFLD
Association between NAPFD and pancreatic enzymes
Previous studies focused on NAFPD
Study | Sample size (FP:NP) | Method of detection | Associated factors | No correlation |
---|---|---|---|---|
Al-Haddad M, et al.[11] | 120 (60/60) | EUS | BMI, hepatic steatosis, alcohol | |
Sepe PS, et al.[10] | 230 (64/166) | EUS | BMI, fatty liver, hyperlipidemia, MetS | DM, pancreatits, pancreatic cancer, age, alcohol, tobacco amylase |
284 (174/110) | EUS | Hepatic steatosis, HTN, Alcohol, tobacco male, age>60 | ||
Lee JS, et al.[13] | 293 (180/113) | Trans-abd ominal US | IR, VAT, ALT, MetS | FBG, LDL-C |
Heni M et al.[12] | 51 | MRI | BMI, VAT, waist circumference | Fatty liver |
Lingvay I, et al. [14] | 79 | MRI | BMI, hyperglycemia | |
Sijens PE, et al.[15] | 36 | MRI | BMI, liver fat | |
Tushuizen ME, et al.[16] | 36 (12/24) | MRI | Beta-cell dysfunction | Fatty liver, VAT |