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Arthritis Research & Therapy

Erschienen in:

01.02.2003 | Commentary

Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis

verfasst von: Erik R Vossenaar, Albert JW Zendman, Walther J van Venrooij

Erschienen in: Arthritis Research & Therapy | Ausgabe 1/2003

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Abstract

Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.

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Titel: Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
verfasst von: Erik R Vossenaar
Albert JW Zendman
Walther J van Venrooij
Publikationsdatum: 01.02.2003
Verlag: BioMed Central
Erschienen in: Arthritis Research & Therapy / Ausgabe 1/2003
Elektronische ISSN: 1478-6362
DOI: https://doi.org/10.1186/ar1027

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