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11.08.2022 | Breast Oncology

Disparities in Primary Breast Cancer Stage at Presentation Among Hispanic Subgroups

verfasst von: Nishwant Swami, MPH, Tiffany Nguyen, MD, Edward Christopher Dee, MD, Idalid Franco, MD, MPH, Yefri A. Baez, MD, Kaitlyn Lapen, MD, Lora Wang, MD, Neha Goel, MD, Brandon A. Mahal, MD, Oluwadamilola M. Fayanju, MD, Narjust Duma, MD, Fumiko Chino, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 13/2022

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Abstract

Background

Although the United States (US) Hispanic population consists of diverse communities, prior breast cancer studies often analyze this group in aggregate. Our aim was to identify differences in breast cancer stage at presentation in the US population, with a particular focus on Hispanic subgroups.

Methods

Data from the National Cancer Database (NCDB) from 2004 to 2017 were used to select women with primary breast cancer; individuals were disaggregated by racial and ethnic subgroup and Hispanic country of origin. Ordinal logistic regression was used to create adjusted odds ratios (aORs) with 95% confidence intervals (CIs), with higher odds representing presentation at later-stage breast cancer. Subgroup analysis was conducted based on tumor receptor status.

Results

Overall, among 2,282,691 women (5.2% Hispanic), Hispanic women were more likely to live in low-income and low-educational attainment neighborhoods, and were also more likely to be uninsured. Hispanic women were also more likely to present at later-stage primary breast cancer when compared with non-Hispanic White women (aOR 1.19, 95% CI 1.18–1.21; p < 0.01). Stage disparities were demonstrated when populations were disaggregated by country of origin, particularly for Mexican women (aOR 1.55, 95% CI 1.51–1.60; p < 0.01). Disparities worsened among both racial and country of origin subgroups in women with triple-negative disease.

Conclusion

Later breast cancer stage at presentation was observed among Hispanic populations when disaggregated by racial subgroup and country of origin. Socioeconomic disparities, as well as uncaptured disparities in access and/or differential care, may drive these observed differences. Future studies with disaggregated data are needed to characterize outcomes in Hispanic communities and develop targeted interventions.

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Titel: Disparities in Primary Breast Cancer Stage at Presentation Among Hispanic Subgroups
verfasst von: Nishwant Swami, MPH
Tiffany Nguyen, MD
Edward Christopher Dee, MD
Idalid Franco, MD, MPH
Yefri A. Baez, MD
Kaitlyn Lapen, MD
Lora Wang, MD
Neha Goel, MD
Brandon A. Mahal, MD
Oluwadamilola M. Fayanju, MD
Narjust Duma, MD
Fumiko Chino, MD
Publikationsdatum: 11.08.2022
Verlag: Springer International Publishing
Erschienen in: Annals of Surgical Oncology / Ausgabe 13/2022
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-022-12302-9

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Disparities in Primary Breast Cancer Stage at Presentation Among Hispanic Subgroups