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American Journal of Clinical Dermatology
Erschienen in: American Journal of Clinical Dermatology 1/2000

01.01.2000 | Review Article

Management of Post-Acne Scarring

What are the Options for Treatment?

verfasst von: Dr Greg J. Goodman

Erschienen in: American Journal of Clinical Dermatology | Ausgabe 1/2000

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Abstract

Post-acne scarring is a very distressing and difficult problem for physician and patient alike. Recently, newer techniques and modifications to older ones may make this hitherto refractory problem more manageable. Options for dealing with post-acne scarring are explored. The patient, his or her overall appearance and the morphology of each scar must be assessed and treatment designed accordingly. To adequately address the patient with scarring, a thorough knowledge of the pathophysiology and anatomy of the different types of scars should be sought. Once an understanding of what the pathology is and where it is occurring is attained, the most pertinent treatment for that scar may be devised. A variety of post-acne scars is produced including superficial macules, dermal troughs, ice picks, multi-channelled fistulous tracts and subcutaneous atrophy.
The wide variety of new treatment methods for post-acne scarring includes newer resurfacing tools such as CO2 and erbium infrared lasers, dermasanding and possibly some future techniques such as non-ablative and radiofrequency resurfacing. Dermal and subcutaneous augmentation with autologous and nonautologous tissue augmentation and the advent of tissue undermining have greatly improved treatment of atrophic scars. Use of punch techniques for sharply marginated scars (such as ice picks) is necessary if this scar morphology is to be treated well. One should attempt to match each scar against an available treatment as far as possible. Many of these techniques may be performed in a single treatment session but repeat treatments are often necessary.
The treatment of hypertrophic acne scarring remains difficult, but silastic sheeting, vascular laser, and intralesional cytotoxics are interesting developments. Most often occurring extra-facially and in males these distressing scars often require multiple treatments and modalities before adequate improvement is achieved.
Literatur
1.
Burton J.L., Cunliffe W.J., Stafford I., et al. The prevalence of acne vulgaris in adolescence. Br J Dermatol 1971; 85: 119–126PubMedCrossRef
2.
Munro-Ashman D. Acne vulgaris in a public school. Trans St John’s Hosp Dermatol Soc 1963; 49: 144–148
3.
Rademaker M, Garioch J.J., Simpson N.B. Acne in schoolchildren: no longer a concern for dermatologists. BMJ 1989; 298: 1217–1219PubMedCrossRef
4.
Bloch B. Metabolism, endocrine glands and skin disease, with special reference to acne vulgaris and xanthoma. Br J Dermatol 1931; 43: 61–68CrossRef
5.
Cunliffe W.J. The acnes. London: Dunitz, 1989
6.
Schacter R.J., Pantel E.S., Glassman G., et al. Acne vulgaris and pyschologic impact on high school students. N Y State J Med 1971; 24: 2886–2899
7.
Goulden V., Stables G.I., Cunliffe W.J. Prevalence of facial acne in adults. J Am Acad Dermatol 1999; 41: 577–580PubMed
8.
Kromayer E. Kosmetische resultate bei anwedung des stanverfahrens. Dermatol Wochenschr 1935; 101: 1306
9.
Cotterill J.A., Cunliffe W.J. Suicide in dermatological patients. Br J Dermatol 1997; 137: 246–250PubMedCrossRef
10.
11.
Strauss J.S., Kligman A.M. Pathologic patterns of the sebaceous gland. J Invest Dermatol 1958; 30: 51–61PubMed
12.
Marples R.R., Leyden J.J., Stewart R.N., et al. The skin microflora in acne vulgaris. J Invest Dermatol 1974; 62: 37–41PubMedCrossRef
13.
Webster G.F., Leyden J.J., Nilsson U.R. Complement activation in acne vulgaris: consumption of complement by comedones. Infect Immun 1979; 26: 183–186PubMed
14.
Tucker S.B., Rogers R.S., Winkelmann R.K., et al. Inflammation in acne vulgaris: leukocyte attraction and cytotoxicity by comedonal material. J Invest Dermatol 1980; 74: 21–25PubMedCrossRef
15.
Strauss J.S. Sebaceous glands. In: Fitzpatrick T.B., Eisen A.Z., Wolff K., et al., editors. Dermatology in general medicine. 4th ed. New York: McGraw-Hill, 1993: 709–726
16.
Knutson D. Ultrastructural observations in acne vulgaris. The normal sebaceous follicle and acne lesions. J Invest Dermatol 1974; 62: 288PubMedCrossRef
17.
Laurentaci G., Diaguardi D. HLA antigens in keloids and hypertrophic scars. Arch Dermatol 1971; 113: 1726CrossRef
18.
Oluwasanmi J.O., Otusanya M.O. Human leucocyte antigens (HLA) and keloids. Arch Dermatol 1983; 2: 127–130
19.
Erlich H.P., Desmouliere A., Cohen I.K., et al. Morphological and immunohistochemical differences between keloid and hypertrophic scar. Am J Pathol 1994; 145 (1): 105–113
20.
Erlich H.P., Hunt T.K. Effects of cortisone and vitamin A on wound healing. Am J Pathol 1968; 167: 324–328
21.
22.
Kromayer E. Rotationsinstrurnente. Ein neues technisches. Veffahren in der dermatologischen Kieinchirurgie. Dermatol Z 1995; 12: 26CrossRef
23.
Kromayer E. Die Heilung der Akne durch ein neues narbenloses. Operationsverfahren: Das Stanzen. Illustr Monatsschr Aerztl Polytech 1905; 27: 101
24.
Kromayer E. Die Heilung der Akne durch ein neues narbenloses Operationsveriahren: Das Stanzen. Munch Med Wochenschr 1905; 52: 942
25.
Kromayer E. Eine neues sichere Epitationsmethode: Das Stanzen. Deutsche Med Wochenschr 1905; 31: 179CrossRef
26.
Kromayer E. Cosmetic treatment of skin complaints. English translation of the second German edition (1929). New York: Oxford University Press, 1930: 9
27.
Kromayer E. Das Frasen in der Kosmetik. Kosmetalogische Rundschau 1933; 4: 61
28.
Kurtin A. Corrective surgical planning of the skin. Arch Dermatol Syph 1953; 68: 389–397CrossRef
29.
LeVan P. Mechanical method of freezing the skin for surgical planing. Arch Dermatol Syph 1954; 69: 739–741CrossRef
30.
Burks J. In: Dermabrasion and chemical peeling. Springfield (Ill): Charles C Thomas, 1979
31.
Yarborough J., Alt T. Current concepts in dermabrasion. J Dermatol Surg Oncol 1987; 13: 595–596PubMed
32.
Alt T. Facial dermabrasion: advantages of the diamond fraise technique. J Dermatol Surg Oncol 1987; 13: 618–624PubMed
33.
Alt T.H., Goodman G.J., Coleman III W.P., et al. Dermabrasion. In: Coleman W.P., Hanke C.W., Alt T.H., et al., editors. Cosmetic surgery of the skin. 2nd ed. St. Louis: Mosby-Year Book Inc., 1997: 112–151
34.
Goodman G.J., Richards S. The treatment of facial wrinkles and scars. Mod Med 1994; 37: 50–63
35.
Goodman G.J. Dermabrasion using tumescent anaesthesia. J Dermatol Surg Oncol 1994; 20: 802–807PubMed
36.
Zisser M., Kaplan B., Moy R.L. Surgical pearl: manual dermabrasion. J Am Acad Dermatol 1995; 33: 105–106PubMedCrossRef
37.
Harris D.R., Noodleman F.R. Combining manual dermasanding with low strength trichloroacetic acid to improve actinically injured skin. J Dermatol Surg Oncol 1994; 20: 436–442PubMed
38.
Tsai R.Y., Wang C.N., Chan H.L. Aluminum oxide crystal microdermabrasion. A new technique for treating facial scarring. Dermatol Surg 1995; 21: 539–542PubMedCrossRef
39.
Bridenstine J.B., Dolezal J.F. Standardizing chemical peel solution formulations to avoid mishaps. Great fluctuations in actual concentrations of trichloroacetic acid. J Dermatol Surg Oncol 1994; 20 (12): 813–816PubMed
40.
Monheit G.D. The Jessner’s-trichloroacetic acid peel. An enhanced medium-depth chemical peel. Dermatol Clin 1995; 13 (2): 277–283PubMed
41.
Chiarello S.E., Resnik B.I., Resnik S.S. The TCA Masque. A new cream formulation used alone and in combination with Jessner’s solution Dermatol Surg 1996 Aug; 22 (8): 687–690PubMedCrossRef
42.
Lowe N.J., Lask G., Griffin M.E., et al. Skin resurfacing with the Ultrapulse carbon dioxide laser. Observations on 100 patients. Dermatol Surg 1995; 21(12): 1025–1029PubMedCrossRef
43.
Lask G., Keller G., Lowe N., et al. Laser skin resurfacing with the SilkTouch flash-scanner for facial rhytides. Dermatol Surg 1995; 21 (12): 1021–1024PubMedCrossRef
44.
Ho C., Nguyen Q., Lowe N.J., et al. Laser resurfacing in pigmented skin. Dermatol Surg 1995; 21 (12): 1035–1037PubMedCrossRef
45.
Dover J.S. CO2 laser resurfacing: why all the fuss? [editorial]. Plast Reconstr Surg 1996; 98 (3): 506–509PubMedCrossRef
46.
Alster T.S., West T.B. Resurfacing of atrophic facial acne scars with a high-energy, pulsed carbon dioxide laser. Dermatol Surg 1996; 22: 151–154PubMedCrossRef
47.
Bernstein L.J., Kauvar A.N.B., Grossman M.C., et al. The short and long term side effects of carbon dioxide laser resurfacing. Dermatol Surg 1997; 23: 519PubMedCrossRef
48.
Laws R.A., Finley E.M., McCollough M.L., et al. Alabaster skin after carbon dioxide laser resurfacing with histologic correlation. Dermatol Surg 1998; 24: 633–636PubMedCrossRef
49.
Dzubow L.M. Dermabrasion. J Dermatol Surg Oncol 1994; 20: 302PubMed
50.
Alt T.H., Goodman G.J., Coleman III W.P., et al. Dermabrasion. In: Coleman III W.P., Hanke C.W., Alt T.H., et al., editors. Cosmetic surgery of the skin — principles and techniques. 2nd ed. St Louis: Mosby Year Books, 1997: 112–151
51.
Fitzpatrick R.E., Goldman M.P. Skin resurfacing with carbon dioxide and erbium lasers. In: Goldman M.P., Fitzpatrick R.E., editors. Cutaneous laser surgery, the art and science of selective photothermolysis. 2nd ed. St Louis: Mosby, 1999: 339–436
52.
McDaniel D.H., Lord J., Ash K., et al. Combined CO2/Erbium: YAG laser resurfacing of perioral rhytides and side to side comparison with Carbon Dioxide laser alone. Dermatol Surg 1999; 25: 285–293PubMedCrossRef
53.
Menaker G.M., Wrone D.A., Williams R.M., et al. Treatment of facial rhytides with a nonablative laser: a Clinical and histologic study. Dermatol Surg 1999; 25: 440–444PubMedCrossRef
54.
Goldberg D.J. Non-ablative subsurface remodelling: Clinical and histologic evaluation of a 1320nm Nd: YAG laser. J Cutan Laser Ther 1999; 1: 153–157PubMed
55.
Kelly K.M., Nelson J.S., Lask G., et al. Cryogen spray cooling in combination with non ablative laser treatment of facial rhytides. Arch Dermatol 1999; 135: 691–694PubMedCrossRef
56.
Tope W.D. Multi-electrode radiofrequency resurfacing of ex vivo human skin. Dermatol Surg 1999; 25: 348–352PubMedCrossRef
57.
Burns R.L., Carruthers A., Langtry J.A., et al. Electrosurgical skin resurfacing: a new bipolar instrument. Dermatol Surg 1999; 25: 583–586CrossRef
58.
West T.B., Alster T.S. Commentary (on electrosurgical resurfacing). Dermatol Surg 1999; 25: 586
59.
Solish N., Raman M., Pollack S.V. Approaches to acne scarring: a review. J Cut Med Surg 1998; 2: S3-24–S3-32
60.
Spangler A.S. New treatment for pitted scars. Arch Dermatol 1957; 76: 708–711CrossRef
61.
Gottlieb S. GAP repair technique. Poster exhibit. Annual Meeting of the American of Dermatology, Dallas, Texas, Dec 1977
62.
Cohen I.S. Fibrel®. Semin Dermatol 1987; 6: 228–237
63.
Multicenter study. Treatment of depressed cutaneous scars with gelatin matrix implant. J Am Acad Dermatol 1987; 16: 1155–1162CrossRef
64.
Swinehart J.M. Pocket grafting with dermal grafts: autologous collagen implants for permanent correction of cutaneous depressions. Am J Cosmet Surg 1995; 12 (4): 321–331
65.
Abergel R.P., Schlaak C.M., Garcia L.D., et al. The laser dermal implant: a new technique for preparation and implantation of autologous dermal grafts for the correction of depressed scars, lip augmentation, and nasolabial folds using silk touch laser technology. Am J Cosmet Surg 1996; 13 (1): 15–18
66.
Goodman G.J. Laser assisted dermal grafting for the correction of cutaneous contour defects. Derm Surg 1997; 23 (2): 95–99CrossRef
67.
Orentreich D.S. Subcutaneous incisionless (Subcision) surgery for the correction of depressed scars and wrinkles. Derm Surg 1995; 21: 543–549CrossRef
68.
Branson D.F. Dermal undermining (scarification) of active rhytids and scars: enhancing the results of CO2 laser skin resurfacing. Aesthetic Surg 1998; 18: 36–37CrossRef
69.
Alster T.S. Improvement of erythematous and hypertrophic scars by the 585nm flashlamp-pumped pulse dye laser. Ann Plast Surg 1994; 32: 186PubMedCrossRef
70.
Yarborough J.N. Scar revision by dermabrasion. In: Roenigk R.K., Roenigk H.H., editors. Dermatologic surgery. New York: Marcel Dekker, 1989: 909–933
71.
Weinstein C. Carbon Dioxide laser resurfacing. In: Coleman III W.P., Hanke C.W., Alt T.H., et al., editors. Cosmetic Surgery of the skin — principles and techniques. 2nd ed. St Louis: Mosby Year Books, 1997: 152–177
72.
Goodman G.J. Facial resurfacing using a high-energy, short-pulse carbon dioxide laser. Australas J Dermatol 1996; 37: 125–131PubMedCrossRef
73.
Teikemeier G., Goldberg D.J. Skin resurfacing with the Erbium: YAG laser. Dermatol Surg 1997; 23: 685–687PubMedCrossRef
74.
Kaufmann R., Hibst R. Pulsed erbium: YAG laser ablation in cutaneous surgery. Lasers Surg Med 1996; 19: 324–330PubMedCrossRef
75.
Solotoff S. Treatment for pitted acne scarring — postauricular punch grafts followed by dermabrasion. J Dermatol Surg Oncol 1986; 12: 1079PubMed
76.
Johnson W. Treatment of pitted scars. Punch transplant technique. J Dermatol Surg Oncol 1986; 12: 260PubMed
77.
Hanke C.W., Coleman W.P. Dermal filler substances. In: Coleman III W.P., Hanke C.W., Alt T.H., et al., editors. Cosmetic surgery of the skin — principles and techniques. 2nd ed. St Louis: Mosby Year Books, 1997: 217–230
78.
Melton J.L., Hanke C.W. Soft tissue augmentation. In: Roenigk R.K., Roenigk H.H.R., editors. Dermatologic surgery. 2nd ed. New York: Marcel Dekker, 1996
79.
Boss Jr W.K., Marko O. Isolagen. In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker Inc, 1998: 335–347
80.
Goodman G.J. Autologous fat transfer and dermal grafting. In: Harahap M., editor. Surgical techniques for cutaneous scar revision. New York: Marcel Dekker Inc., In press
81.
Skouge J.W., Ratner D. Autologous fat transplantation. In: Coleman III W.P., Hanke C.W., Alt T.H., et al., editors. Cosmetic surgery of the skin — principles and techniques. 2nd ed. St Louis: Mosby Year Books, 1997: 206–216
82.
Strauss J.S., Kligman A.M. Observations on dermabrasion. Arch Dermatol 1956; 74: 397–403CrossRef
83.
Caver C.V. Versatile dermabrasion. J Dermatol Surg Oncol 1980; 6: 665–667PubMed
84.
Gravelink J.M., White V.R. Concurrent use of laser skin resurfacing and punch excision in the treatment of facial acne scarring. Dermatol Surg 1998; 24: 527–530CrossRef
85.
Katz B.E., Oca A.G. A controlled study of the effectiveness of spot dermabrasion (§carabrasion’) on the appearance of surgical scars. J Am Acad Dermatol 1991; 24: 462–466PubMedCrossRef
86.
Yarborough Jr J.M. Ablation of facial scars by programmed dermabrasion. J Dermatol Surg Oncol 1988; 14: 292–294PubMed
87.
Whitby D.J., Ferguson M.W. The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development 1991; 112: 651–668PubMed
88.
Harmon C.B., Zelickson B.D., Roenigk R.K., et al. Dermabrasive scar revision. Immunohistochemical and ultrastructural evaluation. Dermatol Surg 1995; 21: 503–508PubMedCrossRef
89.
Chiquet-Ehrisman R, Kalla P., Pearson C.A., et al. Tenascin interferes with fibronectin action. Cell 1988; 53: 383–390CrossRef
90.
Johnson W. Treatment of pitted scars. Punch transplant technique. J Dermatol Surg Oncol 1986; 12: 260PubMed
91.
Ellenbogen R. Invited comment on autologous fat injection. Ann Plast Surg 1990; 24: 297
92.
Ersek R.A. Transplantation of purified autologous fat: a 3-year follow up is disappointing. Plast Reconstr Surg 1991; 87 (2): 219–227PubMedCrossRef
93.
Coleman S.R. Long-term survival of fat transplants: controlled demonstrations. Aesth Plast Surg 1995; 19: 421–425CrossRef
94.
Eppley B.L., Snyders Jr R.V., Winkelmann T., et al. Autologous facial fat transplantation: improved graft maintenance by microbead bioactivation. J Oral Maxillofac Surg 1992; 50 (5): 477–482PubMedCrossRef
95.
Pinski K.S., Roenigk Jr H. Autologous fat transplantation. Long term follow-up. J Dermatol Surg Oncol 1992; 18 (3): 179–182PubMed
96.
Coleman S.R. The technique of periorbital lipoinfiltration. Oper Tech Plast Reconstr Surg 1994; 1: 120CrossRef
97.
Fournier P.F. Facial recontouring with fat grafting. Dermatol Clin 1990; 8 (3): 523–537PubMed
98.
Meschik Z. Vitamin E and adipose tissue. Edinburgh Med J 1944; 51: 486
99.
Katocs Jr. A.S., Largis E.E., Allen D.O. Perfused fat cells: effects of lipolytic agents. J Biol Chem 1973; 248 (14): 5089–5094PubMed
100.
Sidman R.L. The direct effect of insulin on organ cultures of brown fat. Anat Rec 1956; 124: 723PubMedCrossRef
101.
Solomon S.S. Comparative studies of the antilipolytic effect of insulin and adenosine in the perfused fat cell. Horm Metab Res 1980; 12: 601PubMedCrossRef
102.
Smith U. Human adipose tissue in culture studies on the metabolic effects of insulin. Diabetologica 1976; 12: 137CrossRef
103.
Solomon S.S., Duckworth W.C. Effect of antecedent hormone administration on lipolysis in the perfused isolated fat cell. J Lab Clin Med 1976; 88: 984PubMed
104.
Berdeguer P. Five years of experience using fat for leg contouring. Am J Cosm Surg 1995; 12: 221–229
105.
Krulig E. Lipo-injection. Am J Cosm Surg 1987; 4: 123–129
106.
Lewis C.M. The current status of autologous fat grafting. Aesth Plast Surg 1993; 17: 109–112CrossRef
107.
Carpaneda C., Ribeiro M. Study of the histologic alterations and viability of the adipose grafts in humans. Aesth Plast Surg 1990; 17: 43–47CrossRef
108.
Horl H.W., Feller A.M., Biemer E. Technique for liposuction fat re-implantation and long term volume evaluation by magnetic resonance imaging. Ann Plast Surg 1991; 26: 248–258PubMedCrossRef
109.
Johnson G.W. Body contouring by macroinjection of autogenous fat. Am J Cosm Surg 1987; 4: 103–109
110.
Argrus J. Autologous fat transplantation: a 3 year study. Am J Cosm Surg 1987; 4: 95–102
111.
Lexer E. Correcion de los dedulos (Mastoptose) por medio de la implantacion de grasa. San Sebastian Guipuzcoa Media 63: 213, 1921. Translated. In: Hinderer U.T., del Rio J.L., editors. Erich Lexer’ Mammaplasty. Aesth Plast Surg 1992; 16: 101–107
112.
Teimourian B. Blindness following fat injections. Plast Reconstr Surg 1988; 82: 361PubMed
113.
Klein A.W. In favour of double skin testing. J Dermatol Surg Oncol 1989; 15: 263PubMed
114.
Klein A.W. Injectable bovine collagen. In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker, 1998: 125–144
115.
Faigen S. Facial soft tissue augmentation with autologous and homologous injectable collagen (Autologen and Dermalogen). In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker, 1998: 97–124
116.
Terino E.O. Alloderm acellular dermal graft: applications in esthetic and reconstructive soft tissue augmentation. In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker, 1998: 349–377
117.
Streit M., Brand C.U., Braathen L.R. Soft tissue augmentation for treatment of wrinkles and scars of the face. Ther Umsch 1999; 56: 212–218PubMedCrossRef
118.
Piacquadio D.J., Larsen N.E., Denlinger J.L., et al. Hylan B Gel (Hylaform) as a soft tissue augmentation material. In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker, 1998: 349–377
119.
Coleman III W.P., Goodman G.J., Lawrence N. Combining skin resurfacing with soft tissue augmentation. In: Coleman III W.P., Lawrence N., editors. Skin resurfacing. Baltimore: Williams and Wilkins, 1998: 217–234
120.
Laurent T.C., Fraser J.R.E. Hyaluronan. FASEB J 1992; 6: 2397–2404PubMed
121.
Orentreich N.O. Soft tissue augmentation with medical grade silicon. In: Rubin L.R., editor. Biomaterials in reconstructive surgery. St Louis: CV Mosby Co, 1983: 853–881
122.
Duffy D.M. Injectable liquid silicone: new perspectives. In: Klein A.W., editor. Tissue augmentation in clinical practice. Procedures and techniques. New York: Marcel Dekker, 1998: 349–377
123.
Angell M. Shattuck lecture — evaluating the health risks of breast implants: the interplay of medical science, the law, and public opinion. N Engl Med J 1996; 334: 1513–1518CrossRef
124.
Sanchez-Guerrero J., Colditz G.A., Karlson E.W., et al. Silicone breast implants and the risk of connective-tissue diseases and symptoms. N Engl J Med 1995; 332: 1666–1670PubMedCrossRef
125.
Golladay E.S. Treatment of keloids by single intraoperative perilesional injection of repository steroid. South J Med 1988 Jun; 81 (6): 736–738CrossRef
126.
English R.S., Shenefelt P.D. Keloids and hypertrophic scars. Dermatol Surg 1999; 25 (8): 631–638PubMedCrossRef
127.
Elson M.L. Treatment of striae distensae with topical tretinoin. J Dermatol Surg Oncol 1990; 16: 267–270PubMed
128.
Kang S., Kim K.J., Griffiths C.E., et al. Topical tretinoin (retinoic acid) improves early stretch marks. Arch Dermatol 1996; 132: 519–526PubMedCrossRef
129.
Panabiere-Castaings M.H. Retinoic acid in the treatment of keloids. J Dermatol Surg Oncol 1988; 14: 1275–1276PubMed
130.
Daly T.J., Golitz L.E., Weston M.L. A double blind placebo controlled efficacy study of tretinoin cream 0.05% in the treatment of keloids and hypertrophic scars. Clin Res 1986; 34: 159A
131.
Janssen de Limpens A.M.P. The local treatment of hypertrophic scars and keloids with topical retinoic acid. Br J Dermatol 1980; 103: 319CrossRef
132.
Fitzpatrick R.E. Treatment of inflamed hypertrophic scars using intralesional 5-FU. Dermatol Surg 1999; 25: 224–232PubMedCrossRef
133.
Sawada Y., Sone K. Hydration and occlusion treatment for hypertrophic scars and keloids. Br J Plast Surg 1992; 45: 599–603PubMedCrossRef
134.
Merecer N.S. Silicon gel in the treatment of keloid scars. Br J Plast Surg 1989; 42: 83–87
135.
Niessen F.B., Spauwen P.H., Robinson P.H., et al. The use of silicone occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation. Plast Reconstr Surg 1998; 102: 1962–1972PubMedCrossRef
136.
Sawada Y., Sone K. Treatment of scars and keloids with a cream containing silicone oil. Br J Plast Surg 1990; 43: 683–688PubMedCrossRef
137.
Rusciani L., Rossi G., Bono R. Use of cryotherapy in the treatment of keloids. J Dermatol Surg Oncol 1993; 19: 529–534PubMed
138.
Ernst K. Hundeiker M. Results of cryotherapy in 394 patients with hypertrophic scars and keloids. Hautarzt 1995; 46: 462–466PubMedCrossRef
139.
Zouboulis C.C., Blume U., Buttner P., et al. Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series. Arch Dermatol 1993; 129: 1146–1151PubMedCrossRef
140.
Layton A.M., Yip J., Cunliffe W.J. A comparison of intralesional Triamcinolone and cryosurgery in the treatment of acne keloids. Br J Dermatol 1994; 130 (4): 498–501PubMedCrossRef
141.
Alster T.S., Williams C.M. Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser. Lancet 1995; 345 (8959): 1198–2000PubMedCrossRef
142.
Goldman M.P., Fitzpatrick R.E. Laser treatment of scars. Dermatol Surg 1995; 21: 685–687PubMed
143.
Alster T.S. Laser treatment of hypertrophic scars, keloids, and striae. Dermatol Clin 1997; 15: 419–429PubMedCrossRef
144.
Wittenberg G.P., Fabian B.G., Bogomilsky J.L., et al. Prospective single-blind, randomized, controlled study to assess the efficacy of the 585-nm flashlamp-pumped pulsed-dye laser and silicone gel sheeting in hypertrophic scar treatment. Arch Dermatol 1999; 135: 1049–55PubMedCrossRef
145.
Abergel R.P. Failure of carbon dioxide laser excision of keloids. Lasers Surg Med 1989; 9: 382–388CrossRef
146.
Apfelberg D.B., Maser M.R., White D.N., et al. Failure of carbon dioxide laser excision of keloids. Lasers Surg Med 1989; 115: 1107–1111
147.
Hulsbergen Henning J.P., Roskam Y., van Gemert M.J. Treatment of keloids and hypertrophic scars with an argon laser. Lasers Surg Med 1986; 6: 72–75CrossRef
148.
Kelly A.P. Keloids and Hypertrophic Scars. In: Parish L.C., Lask G.P., editors. Aesthetic dermatology. New York: McGraw-Hill, 1991: 58–64
149.
Norris J.E. Superficial x-ray therapy in keloid management: a retrospective study of 24 cases and literature review. Plast Reconstr Surg 1995; 95 (6): 1051–1055PubMedCrossRef
150.
Staley M.J., Richard R.L. Use of pressure to treat hypertrophic burn scars. Adv Wound Care 1997; 10: 44–46PubMed
151.
Costa A.M., Peyrol S., Porto L.C., et al. Mechanical forces induce scar remodelling. Study in non-pressure-treated versus pressure-treated hypertrophic scars. Am J Pathol 1999 Nov; 155: 1671–1679PubMedCrossRef
152.
153.
Peacock E.E. Pharmacologic control of surface scarring in human beings. Am Surg 1981; 193: 592–597
154.
Berman B., Duncan M.R. Short-term keloid treatment in vivo with human interferon alpha-2b results in selective and persistent normalization of keloid fibroblast collagen, glycosaminoglycan, and collagenase production in vitro. J Am Acad Dermatol 1989; 21: 694–701PubMedCrossRef
155.
Larrabee Jr W.F, East C.A., Jaffe H.S., et al. Intralesional interferon gamma treatment of keloids and hypertrophic scars. Arch Otolaryngol Head Neck Surg 1990; 116 (10): 1159–1162PubMedCrossRef
156.
Berman B., Duncan M.R. Pentoxyfilline inhibits the proliferation of human fibroblasts derived from keloid, scleroderma and morphoea skin and their production of collagen, glycosaminoglycans and fibronectin. Br J Dermatol 1990; 123 (3): 339–346PubMedCrossRef
Metadaten
Titel
Management of Post-Acne Scarring
What are the Options for Treatment?
verfasst von
Dr Greg J. Goodman
Publikationsdatum
01.01.2000
Verlag
Springer International Publishing
Erschienen in
American Journal of Clinical Dermatology / Ausgabe 1/2000
Print ISSN: 1175-0561
Elektronische ISSN: 1179-1888
DOI
https://doi.org/10.2165/00128071-200001010-00001

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