Lipomatous cortical dysplasia with callosal lipoma: a rare association

Excerpt

Intracranial lipomas are rare benign congenital malformations commonly thought to be related to the abnormal persistence and mal-differentiation of the meninx primitiva during the development of the subarachnoid cisterns, a theory first proposed by Verga [1]. The existence of the lipoma might contribute to the formation of focal cortical dysplasia because of the physical interruption of the cortex and focal perfusion insufficiency [2]. The images are of a 14-year-old girl who presented with a 2-year history of recurrent complex partial seizures. The non-enhanced axial CT image (Fig. 1) shows a linear hypodense area of fat attenuation in the left frontal lobe extending medially to the interhemispheric fissure. Linear calcifications bordering the lipoma are seen posteriorly. Another lesion of fat attenuation is seen in the midline at the region of the corpus callosum. Figure 2 is an axial T1-weighted MR image with a high-signal lesion in the left frontal lobe with a surrounding thickened dysplastic cortex. The pericallosal lipoma is also shown. These images present a rare association of a left frontal lipomatous mass with cortical dysplasia and a hypogenetic corpus callosum with a pericallosal lipoma.

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