Erschienen in:
01.10.2010 | Case report
Macular vitelliform lesion in desferrioxamine-related retinopathy
verfasst von:
Mohamed A. Genead, Gerald A. Fishman, Anastasios Anastasakis, Martin Lindeman
Erschienen in:
Documenta Ophthalmologica
|
Ausgabe 2/2010
Einloggen, um Zugang zu erhalten
Abstract
To report a case of a macular vitelliform lesion associated with desferrioxamine treatment. Ocular, electrophysiological, psychophysical, perimetric, fluorescein angiographic, fundus autofluorescence, and spectral-domain OCT examinations were obtained on a 45-year-old Caucasian woman with thalassemia major treated with blood transfusions and desferrioxamine. The patient was observed to have a vitelliform macular lesion in the right eye with a hypopigmented macular lesion and retinal pigment mottling in the left. At the most recent follow-up visit, best-corrected visual acuity was 20/70 in the right eye and 20/25 in left. Full-field electroretinogram (ERG) testing showed normal cone and rod responses. Mild localized elevations of rod psychophysical thresholds were found. A vitelliform macular lesion can develop in patients treated with desferrioxamine. Some such patients may not show diffuse photoreceptor cell functional loss as determined by electrophysiological testing.