nach oben

Clinical Reviews in Allergy & Immunology

Erschienen in:

03.03.2016

Medical Complications of Tattoos: A Comprehensive Review

verfasst von: Parvez S. Islam, Christopher Chang, Carlo Selmi, Elena Generali, Arthur Huntley, Suzanne S. Teuber, M. Eric Gershwin

Erschienen in: Clinical Reviews in Allergy & Immunology | Ausgabe 2/2016

Einloggen, um Zugang zu erhalten

Abstract

Tattoos are defined as the introduction of exogenous pigments into the dermis in order to produce a permanent design. This process may occur unintentional or may be deliberately administered for cosmetic or medical reasons. Tattoos have been around for over 5000 years and over time have evolved to represent a common cosmetic practice worldwide. Currently, adverse reactions are relatively rare and generally unpredictable and predominantly include immune-mediated reactions and skin infections. Along with better healthcare standards and more stringent public health mandates such as the provision of disposable needles, major infectious complications related to hepatitis and human retroviral infections have decreased significantly. When they do occur, skin infections are most frequently associated with Staphylococcus aureus or Streptococcus pyogenes. The aim of this study is to review the types and rates of medical complications of permanent tattoos. PubMed search and search dates were open ended. Acute local inflammation is the most common complication, but infections, allergic contact dermatitis, and other inflammatory or immune responses that are not well-characterized may occur. As many patients with immune reactions to tattoos do not react on skin or patch testing, it is postulated that the antigens contained in dyes or pigments are such small molecules that they need to be haptenized in order to become immunogenic. Red ink is associated more frequently with long-term reactions, including granulomatous and pseudolymphomatous phenomena or morphea-like lesions and vasculitis. Exacerbation of preexisting psoriasis, atopic dermatitis, and pyoderma gangrenosum may occur after tattooing. There is no well-defined association between cancer and tattoos. The treatment of tattoo-related complications may include local destructive measures (cryotherapy, electro-surgery, dermabrasion, chemical destruction, ablative laser destruction), surgical excision, and thermolysis of the pigment using Q-switched laser therapy.

Sperry K (1991) Tattoos and tattooing. Part I: history and methodology. Am J Forensic Med Pathol 12:313–319CrossRefPubMed

Kluger N, Koljonen V (2012) Tattoos, inks, and cancer. Lancet Oncol 13:e161–e168CrossRefPubMed

Wenzel SM, Welzel J, Hafner C, Landthaler M, Baumler W (2010) Permanent make-up colorants may cause severe skin reactions. Contact Dermatitis 63:223–227CrossRefPubMed

Kierstein L, Kjelskau KC (2015) Tattoo as art, the drivers behind the fascination and the decision to become tattooed. Curr Probl Dermatol 48:37–40CrossRefPubMed

Kean WF, Tocchio S, Kean M, Rainsford KD (2013) The musculoskeletal abnormalities of the Similaun Iceman (“OTZI”): clues to chronic pain and possible treatments. Inflammopharmacology 21:11–20CrossRefPubMedPubMedCentral

Pesapane F, Nazzaro G, Gianotti R, Coggi A (2014) A short history of tattoo. JAMA Dermatol 150:145CrossRefPubMed

Laumann AE, Derick AJ (2006) Tattoos and body piercings in the United States: a national data set. J Am Acad Dermatol 55:413–421CrossRefPubMed

Cegolon L, Mastrangelo G, Mazzoleni F et al (2010) Body art in 4,277 Italian secondary school adolescents: prevalence and associations with personal and family characteristics. Fam Med 42:273–279PubMed

Laux P, Tralau T, Tentschert J et al (2015) A medical-toxicological view of tattooing. Lancet 387(10016):395-402

10.

Klugl I, Hiller KA, Landthaler M, Baumler W (2010) Incidence of health problems associated with tattooed skin: a nation-wide survey in German-speaking countries. Dermatology 221:43–50CrossRefPubMed

11.

Simunovic C, Shinohara MM (2014) Complications of decorative tattoos: recognition and management. Am J Clin Dermatol 15:525–536CrossRefPubMed

12.

Korner R, Pfohler C, Vogt T, Muller CS (2013) Histopathology of body art revisited - analysis and discussion of 19 cases. J Dtsch Dermatol Ges 11:1073–1080PubMed

13.

Mayers LB, Judelson DA, Moriarty BW, Rundell KW (2002) Prevalence of body art (body piercing and tattooing) in university undergraduates and incidence of medical complications. Mayo Clin Proc 77:29–34CrossRefPubMed

14.

Forbes GB (2001) College students with tattoos and piercings: motives, family experiences, personality factors, and perception by others. Psychol Rep 89:774–786CrossRefPubMed

15.

LeBlanc PM, Hollinger KA, Klontz KC (2012) Tattoo ink-related infections—awareness, diagnosis, reporting, and prevention. N Engl J Med 367:985–987CrossRefPubMed

16.

Beute TC, Miller CH, Timko AL, Ross EV (2008) In vitro spectral analysis of tattoo pigments. Dermatol Surg 34:508–515, discussion 515–506PubMed

17.

Forte G, Petrucci F, Cristaudo A, Bocca B (2009) Market survey on toxic metals contained in tattoo inks. Sci Total Environ 407:5997–6002CrossRefPubMed

18.

Maeda N (1964) Histologic study of the tattoo mark. Dermatol Trop Ecol Geogr 18:207–216PubMed

19.

Lea PJ, Pawlowski A (1987) Human tattoo. Electron microscopic assessment of epidermis, epidermal-dermal junction, and dermis. Int J Dermatol 26:453–458CrossRefPubMed

20.

Fujita H, Nishii Y, Yamashita K, Kawamata S, Yoshikawa K (1988) The uptake and long-term storage of India ink particles and latex beads by fibroblasts in the dermis and subcutis of mice, with special regard to the non-inflammatory defense reaction by fibroblasts. Arch Histol Cytol 51:285–294CrossRefPubMed

21.

Liszewski W, Kream E, Helland S, Cavigli A, Lavin BC, Murina A (2015) The demographics and rates of tattoo complications, regret, and unsafe tattooing practices: a cross-sectional study. Dermatol Surg 41:1283–1289CrossRefPubMed

22.

Nishioka S, Gyorkos TW (2001) Tattoos as risk factors for transfusion-transmitted diseases. Int J Infect Dis 5:27–34CrossRefPubMed

23.

Khunger N, Molpariya A, Khunger A (2015) Complications of tattoos and tattoo removal: stop and think before you ink. J Cutan Aesthet Surg 8:30–36CrossRefPubMedPubMedCentral

24.

Kluger N (2009) Bacterial endocarditis and body art: suggestions for an active prevention. Int J Cardiol 136:112–113CrossRefPubMed

25.

Kluger N (2012) Acute complications of tattooing presenting in the ED. Am J Emerg Med 30:2055–2063CrossRefPubMed

26.

Conaglen PD, Laurenson IF, Sergeant A, Thorn SN, Rayner A, Stevenson J (2013) Systematic review of tattoo-associated skin infection with rapidly growing mycobacteria and public health investigation of a cluster in Scotland, 2010. Euro Surveill 18:20553

27.

Falsey RR, Kinzer MH, Hurst S et al (2013) Cutaneous inoculation of nontuberculous mycobacteria during professional tattooing: a case series and epidemiologic study. Clin Infect Dis 57:e143–e147CrossRefPubMed

28.

Sergeant A, Conaglen P, Laurenson IF et al (2013) Mycobacterium chelonae infection: a complication of tattooing. Clin Exp Dermatol 38:140–142CrossRefPubMed

29.

Mittal RR, Singla A, Gupta R (2002) Inoculation leprosy after tattooing. Indian Journal of Dermatology, Venereology and Leprology. 68:116

30.

Singh G, Tutakne MA, Tiwari VD, Dutta RK (1985) Inoculation leprosy developing after tattooing—a case report. Indian J Lepr 57:887–888PubMed

31.

Cowan RK, Martens MG (1993) Toxic shock syndrome mimicking pelvic inflammatory disease presumably resulting from tattoo. South Med J 86:1427–1431CrossRefPubMed

32.

Chowfin A, Potti A, Paul A, Carson P (1999) Spinal epidural abscess after tattooing. Clin Infect Dis 29:225–226CrossRefPubMed

33.

Satchithananda DK, Walsh J, Schofield PM (2001) Bacterial endocarditis following repeated tattooing. Heart 85:11–12CrossRefPubMedPubMedCentral

34.

Tse D, Khan S, Clarke S (2009) Bacterial endocarditis complicating body art. Int J Cardiol 133:e28–e29CrossRefPubMed

35.

Korman TM, Grayson ML, Turnidge JD (1997) Polymicrobial septicaemia with Pseudomonas aeruginosa and Streptococcus pyogenes following traditional tattooing. J Infect 35:203CrossRefPubMed

36.

Kluger N, Saarinen K (2014) Aspergillus fumigatus infection on a home-made tattoo. Br J Dermatol 170:1373–1375CrossRefPubMed

37.

Wanat KA, Tyring S, Rady P, Kovarik CL (2014) Human papillomavirus type 27 associated with multiple verruca within a tattoo: report of a case and review of the literature. Int J Dermatol 53:882–884CrossRefPubMed

38.

Lee-Wong M, Karagic M, Silverberg N (2009) Anaphylactic reaction to permanent tattoo ink. Ann Allergy Asthma Immunol 103:88–89CrossRefPubMed

39.

Clark RA, Chong B, Mirchandani N et al (2006) The vast majority of CLA+ T cells are resident in normal skin. J Immunol 176:4431–4439CrossRefPubMed

40.

Schaerli P, Ebert L, Willimann K et al (2004) A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med 199:1265–1275CrossRefPubMedPubMedCentral

41.

Brady BG, Gold H, Leger EA, Leger MC (2015) Self-reported adverse tattoo reactions: a New York City Central Park study. Contact Dermatitis 73:91–99CrossRefPubMed

42.

Thum CK, Biswas A (2015) Inflammatory complications related to tattooing: a histopathological approach based on pattern analysis. Am J Dermatopathol 37:54–66CrossRefPubMed

43.

Winkelmann RK, Harris RB (1979) Lichenoid delayed hypersensitivity reactions in tattoos. J Cutan Pathol 6:59–65CrossRefPubMed

44.

Garcovich S, Carbone T, Avitabile S, Nasorri F, Fucci N, Cavani A (2012) Lichenoid red tattoo reaction: histological and immunological perspectives. Eur J Dermatol 22:93–96PubMed

45.

Anolik R, Mandal R, Franks AG Jr (2010) Sarcoidal tattoo granuloma. Dermatol Online J 16:19PubMed

46.

Madan NK, Vallonthaiel AG, Arava S, Ali MF, Goyal M, Singh MK (2015) Perforating granuloma annulare in a young male following application of the tattoo. Ind Dermatol Online J 6:296–298CrossRef

47.

Wood A, Hamilton SA, Wallace WA, Biswas A (2014) Necrobiotic granulomatous tattoo reaction: report of an unusual case showing features of both necrobiosis lipoidica and granuloma annulare patterns. Am J Dermatopathol 36:e152–e155CrossRefPubMed

48.

Gaudron S, Ferrier-Le Bouedec MC, Franck F, D’Incan M (2015) Azo pigments and quinacridones induce delayed hypersensitivity in red tattoos. Contact Dermatitis 72:97–105CrossRefPubMed

49.

Ortiz AE, Alster TS (2012) Rising concern over cosmetic tattoos. Dermatol Surg 38:424–429CrossRefPubMed

50.

Bernstein EF (2015) A widespread allergic reaction to black tattoo ink caused by laser treatment. Lasers Surg Med 47:180–182CrossRefPubMed

51.

Jacob SE, Castanedo-Tardan MP, Blyumin ML (2008) Inflammation in green (chromium) tattoos during patch testing. Dermatitis 19:E33–E34PubMed

52.

Yoong C, Vun YY, Spelman L, Muir J (2010) True blue football fan: tattoo reaction confined to blue pigment. Australas J Dermatol 51:21–22CrossRefPubMed

53.

Chapman G, Hildyard CA (2014) Two decades later: a delayed red ink tattoo reaction. BMJ Case Rep 2014 doi:10.1136/bcr-2013-201726

54.

Sonnen G (2007) Type IV hypersensitivity reaction to a temporary tattoo. Proc Bayl Univ Med Cent 20:36–38PubMedPubMedCentral

55.

Hessert MJ, Devlin J (2011) Ink sick: tattoo ink hypersensitivity vasculitis. Am J Emerg Med 29:1237.e1233–1234

56.

Serup J, Hutton Carlsen K (2014) Patch test study of 90 patients with tattoo reactions: negative outcome of allergy patch test to baseline batteries and culprit inks suggests allergen(s) are generated in the skin through haptenization. Contact Dermatitis 71:255–263CrossRefPubMed

57.

Hutton Carlsen K, Serup J (2014) Photosensitivity and photodynamic events in black, red and blue tattoos are common: a ‘Beach Study’. J Eur Acad Dermatol Venereol 28:231–237CrossRefPubMed

58.

Bassi A, Campolmi P, Cannarozzo G et al (2014) Tattoo-associated skin reaction: the importance of an early diagnosis and proper treatment. Biomed Res Int 2014:354608

59.

Kaplan DH, Igyarto BZ, Gaspari AA (2012) Early immune events in the induction of allergic contact dermatitis. Nat Rev Immunol 12:114–124PubMedPubMedCentral

60.

Aptula AO, Roberts DW, Pease CK (2007) Haptens, prohaptens and prehaptens, or electrophiles and proelectrophiles. Contact Dermatitis 56:54–56CrossRefPubMed

61.

Kaur RR, Kirby W, Maibach H (2009) Cutaneous allergic reactions to tattoo ink. J Cosmet Dermatol 8:295–300CrossRefPubMed

62.

Cruz FA, Lage D, Frigerio RM, Zaniboni MC, Arruda LH (2010) Reactions to the different pigments in tattoos: a report of two cases. An Bras Dermatol 85:708–711CrossRefPubMed

63.

Huynh TN, Jackson JD, Brodell RT (2014) Tattoo and vaccination sites: possible nest for opportunistic infections, tumors, and dysimmune reactions. Clin Dermatol 32:678–684CrossRefPubMed

64.

Antony FC, Harland CC (2003) Red ink tattoo reactions: successful treatment with the Q-switched 532 nm Nd:YAG laser. Br J Dermatol 149:94–98CrossRefPubMed

65.

Kluger N (2013) Sarcoidosis on tattoos: a review of the literature from 1939 to 2011. Sarcoidosis Vasc Diffuse Lung Dis 30:86–102PubMed

66.

Shinohara MM, Nguyen J, Gardner J, Rosenbach M, Elenitsas R (2012) The histopathologic spectrum of decorative tattoo complications. J Cutan Pathol 39:1110–1118CrossRefPubMed

67.

Kazandjieva J, Tsankov N (2007) Tattoos: dermatological complications. Clin Dermatol 25:375–382CrossRefPubMed

68.

Marchesi A, Parodi PC, Brioschi M et al (2014) Tattoo ink-related cutaneous pseudolymphoma: a rare but significant complication. Case report and review of the literature. Aesthetic Plast Surg 38:471–478CrossRefPubMed

69.

Kluger N, Vermeulen C, Moguelet P et al (2010) Cutaneous lymphoid hyperplasia (pseudolymphoma) in tattoos: a case series of seven patients. J Eur Acad Dermatol Venereol 24:208–213CrossRefPubMed

70.

Kluger N, Phan A, Debarbieux S, Balme B, Thomas L (2008) Skin cancers arising in tattoos: coincidental or not? Dermatology 217:219–221CrossRefPubMed

71.

Kluger N, Minier-Thoumin C, Plantier F (2008) Keratoacanthoma occurring within the red dye of a tattoo. J Cutan Pathol 35:504–507CrossRefPubMed

72.

Kluger N, Mathelier-Fusade P, Moguelet P (2009) Scleroderma-like reaction restricted to the red parts of a tattoo. Acta Derm Venereol 89:95–96CrossRefPubMed

73.

Lobato-Berezo A, Churruca-Grijelmo M, Martinez-Perez M et al (2014) Dermatofibroma arising within a black tattoo. Case Rep Dermatol Med 2014:745304

74.

Bittencourt Mde J, Miranda MF, Parijos AM, Mesquita LB, Fonseca DM, Jambo DA (2013) Dermatofibroma in a black tattoo: report of a case. An Bras Dermatol 88:614–616CrossRefPubMed

75.

Reddy KK, Hanke CW, Tierney EP (2011) Malignancy arising within cutaneous tattoos: case of dermatofibrosarcoma protuberans and review of literature. J Drugs Dermatol 10:837–842PubMed

76.

Baker PA, O’Dowd GJ, Khan IU (2005) Dermatofibrosarcoma protuberans arising in a decorative tattoo. Sarcoma 9:37–41CrossRefPubMedPubMedCentral

77.

Ghorpade A (2015) Tattoo-induced psoriasis. Int J Dermatol 54:1180–11822

78.

Litvinov IV, Sasseville D (2014) Pyoderma gangrenosum triggered by red tattoo dye. CMAJ 186:935CrossRefPubMedPubMedCentral

79.

Tendas A, Niscola P, Barbati R et al (2011) Tattoo related pyoderma/ectyma gangrenous as presenting feature of relapsed acute myeloid leukaemia: an exceptionally rare observation. Injury 42:546–547CrossRefPubMed

80.

Jacobson S, Martin DB, Deng A, Cooper JZ (2008) Pyoderma gangrenosum following tattoo placement in a patient with acute myelogenous leukemia. J Dermatolog Treat 19:58–60CrossRefPubMed

81.

Deeken A, Jefferson J, Hawkinson D, Fraga GR (2014) Localized chronic fibrosing vasculitis in a tattoo: a unique adverse tattoo reaction. Am J Dermatopathol 36:e81–e83CrossRefPubMed

82.

Guy GP Jr, Thomas CC, Thompson T, Watson M, Massetti GM, Richardson LC (2015) Vital signs: melanoma incidence and mortality trends and projections—United States, 1982–2030. MMWR Morb Mortal Wkly Rep 64:591–596PubMed

83.

Rogers HW, Weinstock MA, Feldman SR, Coldiron BM (2015) Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012. JAMA Dermatol 151:1081–1086CrossRefPubMed

84.

Birnie AJ, Kulkarni K, Varma S (2006) Basal cell carcinoma arising in a tattoo. Clin Exp Dermatol 31:820–821CrossRefPubMed

85.

Souza ES, Rocha Bde O, Batista Eda S, Oliveira RF, Farre L, Bittencourt AL (2014) T-cell-predominant lymphoid hyperplasia in a tattoo. An Bras Dermatol 89:1019–1021CrossRefPubMedPubMedCentral

86.

Sweeney SA, Hicks LD, Ranallo N, Snyder N t, Soldano AC (2013) Perforating granulomatous dermatitis reaction to exogenous tattoo pigment: a case report and review of the literature. Am J Dermatopathol 35:754–756CrossRefPubMed

87.

Luebberding S, Alexiades-Armenakas M (2014) New tattoo approaches in dermatology. Dermatol Clin 32:91–96CrossRefPubMed

88.

England RW, Vogel P, Hagan L (2002) Immediate cutaneous hypersensitivity after treatment of tattoo with Nd:YAG laser: a case report and review of the literature. Ann Allergy Asthma Immunol 89:215–217CrossRefPubMed

89.

Sperry K (1992) Tattoos and tattooing. Part II: gross pathology, histopathology, medical complications, and applications. Am J Forensic Med Pathol 13:7–17CrossRefPubMed

90.

Ho DD, London R, Zimmerman GB, Young DA (2002) Laser-tattoo removal—a study of the mechanism and the optimal treatment strategy via computer simulations. Lasers Surg Med 30:389–397CrossRefPubMed

91.

Weiss ET, Geronemus RG (2011) Combining fractional resurfacing and Q-switched ruby laser for tattoo removal. Dermatol Surg 37:97–99CrossRefPubMed

92.

Ho SG, Goh CL (2015) Laser tattoo removal: a clinical update. J Cutan Aesthet Surg 8:9–15CrossRefPubMedPubMedCentral

93.

Douglas MJ, Swenerton JE (2002) Epidural anesthesia in three parturients with lumbar tattoos: a review of possible implications. Can J Anaesth 49:1057–1060CrossRefPubMed

94.

Ferraz IL, Barros GA, Ferreira Neto PG et al (2015) Does spinal block through tattooed skin cause histological changes in nervous tissue and meninges?: an experimental model in rabbits. Reg Anesth Pain Med 40:533–538CrossRefPubMed

95.

Serup J (2015) Seamless prevention of adverse events from tattooing: integrated strategy emphasising the customer-tattooist interaction. Curr Probl Dermatol 48:236–247CrossRefPubMed

Titel: Medical Complications of Tattoos: A Comprehensive Review
verfasst von: Parvez S. Islam
Christopher Chang
Carlo Selmi
Elena Generali
Arthur Huntley
Suzanne S. Teuber
M. Eric Gershwin
Publikationsdatum: 03.03.2016
Verlag: Springer US
Erschienen in: Clinical Reviews in Allergy & Immunology / Ausgabe 2/2016
Print ISSN: 1080-0549
Elektronische ISSN: 1559-0267
DOI: https://doi.org/10.1007/s12016-016-8532-0

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

Medical Complications of Tattoos: A Comprehensive Review

Abstract

Neu im Fachgebiet HNO

Akuter Schwindel: Wann lohnt sich eine MRT?

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Update HNO

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2016

Eosinophilic Gastroenteritis and Colitis: a Comprehensive Review

The Eosinophil in Infection

The Eosinophil in Health and Disease: from Bench to Bedside and Back

Biological Modulators in Eosinophilic Diseases

The Role and Immunobiology of Eosinophils in the Respiratory System: a Comprehensive Review

Eosinophilic Skin Diseases: A Comprehensive Review

Neu im Fachgebiet HNO

Akuter Schwindel: Wann lohnt sich eine MRT?

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

HNO-Op. auch mit über 90?

Intrakapsuläre Tonsillektomie gewinnt an Boden

Update HNO