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Die Onkologie

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01.01.2008 | Leitthema

Mikronährstoffsupplemente bei onkologischen Patienten

Rationale für die Empfehlung

verfasst von: Prof. Dr. H.-K. Biesalski

Erschienen in: Die Onkologie | Ausgabe 1/2008

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Zusammenfassung

Vitamine, Minerale und Spurenelemente, insbesondere Antioxidanzien, werden von bis zu 70% der onkologischen Patienten in unterschiedlichsten Kombinationen und Konzentrationen eingenommen. Die Rationale für die Einnahme ist unterschiedlich und oft auch unbegründet. Während normal dosierte Mikronährstoffpräparate aufgrund der oft bestehenden Mangelernährung unkritisch sind, ist bei den vielfach empfohlenen hoch dosierten Präparaten, v. a. den Antioxidanzien, die Datenlage unklar und es ist nicht sicher, inwieweit hier statt des positiven Effekts ein negativer eintreten kann. Die Radio- und Chemotherapie wirkt unter anderem über die Bildung reaktiver Sauerstoffverbindungen (ROS), die wiederum durch Antioxidanzien abgefangen werden. ROS sind aber auch für Nebenwirkungen mitverantwortlich, sodass Antioxidanzien hier eher nützlich sein könnten. Dies gilt es bei der Beurteilung der wissenschaftlichen Evidenz für den Einsatz von Antioxidanzien abzuwägen.

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Titel: Mikronährstoffsupplemente bei onkologischen Patienten
Rationale für die Empfehlung
verfasst von: Prof. Dr. H.-K. Biesalski
Publikationsdatum: 01.01.2008
Verlag: Springer-Verlag
Erschienen in: Die Onkologie / Ausgabe 1/2008
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI: https://doi.org/10.1007/s00761-007-1291-z

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