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Cognitive Therapy and Research

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01.08.2015 | Original Article

Modeling the Neuroanatomical and Neurocognitive Mechanisms of Cognitive Insight in Non-clinical Subjects

verfasst von: Lisa Buchy, Martin Lepage

Erschienen in: Cognitive Therapy and Research | Ausgabe 4/2015

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Abstract

Cognitive insight, measured through one’s “Self-Reflectiveness” and “Self-Certainty”, involves the evaluation and correction of distorted beliefs and interpretations, and is important for clinical insight (i.e., awareness of illness) in psychosis. In psychosis, cognitive insight may depend on hippocampal and ventrolateral prefrontal cortical (VLPFC) structure, and verbal memory and executive functions. We explored whether similar relations exist in non-clinical participants. Fifty-one non-clinical subjects completed the Beck Cognitive Insight Scale. Hippocampal volumes and VLPFC thickness were examined using FreeSurfer, and verbal memory and reasoning and problem solving was examined in a subset of the sample (n = 27). Significant correlations emerged between Self-Certainty and left VLPFC thickness, but not Self-Reflectiveness and VLPFC, or either cognitive insight measure and hippocampal volumes. Neither Self-Reflectiveness nor Self-Certainty correlated with neurocognitive functioning. These results provide a framework of mechanisms underlying cognitive insight in non-clinical samples, and allow evaluation of how these process may become dysfunctional in psychosis.

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Titel: Modeling the Neuroanatomical and Neurocognitive Mechanisms of Cognitive Insight in Non-clinical Subjects
verfasst von: Lisa Buchy
Martin Lepage
Publikationsdatum: 01.08.2015
Verlag: Springer US
Erschienen in: Cognitive Therapy and Research / Ausgabe 4/2015
Print ISSN: 0147-5916
Elektronische ISSN: 1573-2819
DOI: https://doi.org/10.1007/s10608-015-9674-8

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