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Erschienen in:
01.11.2004 | Original article
Modified extraperitoneal endoscopic separation of parts for abdominal compartment syndrome
Erschienen in: Surgical Endoscopy | Ausgabe 11/2004
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Background
Standard therapy for abdominal compartment syndrome (ACS) is laparotomy and temporary abdominal wall closure with significant morbidity. The component separation technique allows for difficult abdominal closure. We studied a modified extraperitoneal endoscopic separation of parts technique on an animal model of ACS.
Methods
Twelve anesthetized pigs were instrumented for measurement of central venous pressure, arterial pressure, pulmonary artery pressure, pulmonary capillary wedge pressure, cardiac output, and intraabdominal pressure (IAP). ACS to 25 mmHg was created by infusing saline into an intraabdominally placed bag. Animals were divided in two equal groups. Pigs in group A underwent minimally invasive resection of the nerves supplying the rectus muscles bilaterally. Pigs in group B underwent minimally invasive modified component separation technique bilaterally. Change in IAP and other physiological parameters were recorded.
Results
(Group A) IAP increased significantly from 7.3 mmHg ± 3.8 to 25.2 mmHg ± 1.5 with infusion of saline. Following nerve transection on the right side there was a nonsignificant decrease in IAP from 25.2 mmHg ± 1.5 to 22.3 mmHg ± 1.4 and following nerve transection on the left side there was a further decrease in IAP to 20.3 mmHg ± 1.9. (Group B) IAP increased significantly from 3.8 mmHg ± 0.4 to 24.7 mmHg ± 0.5 with infusion of saline. Following separation of parts on the right side there was a significant decrease in IAP from 24.7 mmHg ± 0.5 to 15.0 mmHg ± 1.7 and there was a further decrease in IAP to 11.3 mmHg ± 1.4 following separation of parts on the left side. The only significant change in the physiological parameters measured was observed in CVP in both groups.
Conclusion
We present a porcine model of extraperitoneal endoscopic release of abdominal wall components as a treatment option for ACS.