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Arthritis Research & Therapy
Erschienen in: Arthritis Research & Therapy 2/2005

01.03.2005 | Review

Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?

verfasst von: Vivianne Malmström, Christina Trollmo, Lars Klareskog

Erschienen in: Arthritis Research & Therapy | Sonderheft 2/2005

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Abstract

Rheumatoid arthritis (RA) is a common destructive inflammatory disease that affects 0.5–1% of the population in many countries. Even though several new treatments have been introduced for patients with RA, a considerable proportion of patients do not benefit from these, and the need for alternative treatment strategies is clear. This review explores the potential for a therapy targeting the adaptive immune system by modulating co-stimulation of T cells with a CTLA4–Ig fusion protein (abatacept).
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Metadaten
Titel
Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?
verfasst von
Vivianne Malmström
Christina Trollmo
Lars Klareskog
Publikationsdatum
01.03.2005
Verlag
BioMed Central
Erschienen in
Arthritis Research & Therapy / Ausgabe Sonderheft 2/2005
Elektronische ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar1505

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