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Pediatric Nephrology
Erschienen in: Pediatric Nephrology 5/2012

01.05.2012 | Review

Monitoring and managing viral infections in pediatric renal transplant recipients

verfasst von: Patrizia Comoli, Fabrizio Ginevri

Erschienen in: Pediatric Nephrology | Ausgabe 5/2012

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Abstract

Viral infections remain a significant cause of morbidity and mortality following renal transplantation. The pediatric cohort is at high risk of developing virus-related complications due to immunological naiveté and the increased alloreactivity risk that requires maintaining a heavily immunosuppressive environment. Although cytomegalovirus is the most common opportunistic pathogen seen in transplant recipients, numerous other viruses may affect clinical outcome. Recent technological advances and novel antiviral therapy have allowed implementation of viral and immunological monitoring protocols and adoption of prophylactic or preemptive treatment approaches in high-risk groups. These strategies have led to improved viral infection management in the immunocompromised host, with significant impact on outcome. We review the major viral infections seen following kidney transplantation and discuss strategies for preventing and managing these pathogens.
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Metadaten
Titel
Monitoring and managing viral infections in pediatric renal transplant recipients
verfasst von
Patrizia Comoli
Fabrizio Ginevri
Publikationsdatum
01.05.2012
Verlag
Springer-Verlag
Erschienen in
Pediatric Nephrology / Ausgabe 5/2012
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-011-1812-2

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