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European Radiology
Erschienen in: European Radiology 8/2010

01.08.2010 | Interventional

MR-guided liver tumor ablation employing open high-field 1.0T MRI for image-guided brachytherapy

Erschienen in: European Radiology | Ausgabe 8/2010

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Abstract

Objective

To determine the feasibility and safety of image-guided brachytherapy employing a modified open high-field MR system.

Methods

This is a follow-up study of a development project enabling technologies for interventional use of 1.0T open MRI. Modifications included coils and in-bore visualization, fluoroscopic sequences and user interfaces. We recruited 104 patients with 224 liver malignancies to receive MR-guided brachytherapy. Interventions were performed >20 min after Gd-EOB-DTPA. We recorded interventional parameters including the intervention time (from acquisition of the first scout until the final sequence for brachytherapy treatment planning). Two reviewers assessed MR-fluoroscopic images in comparison to plain CT as used in CT intervention, applying a rating scale of 1–10. Statistical analysis included Friedman and Kendall’s W tests.

Results

We employed freehand puncture with interactive dynamic imaging for navigation. Technical success rate was 218 complete ablations in 224 tumours (97%). The median intervention time was 61 min. We recorded no adverse events related to the use of MRI. No major complications occurred. The rate of minor complications was 4%. Local control at 3 months was 96%. Superiority of MR-fluoroscopic, Gd-EOB-DTPA-enhanced images over plain CT was highly significant (P < 0.001).

Conclusion

MR-guided brachytherapy employing open high-field MRI is feasible and safe.
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Metadaten
Titel
MR-guided liver tumor ablation employing open high-field 1.0T MRI for image-guided brachytherapy
Publikationsdatum
01.08.2010
Erschienen in
European Radiology / Ausgabe 8/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1751-5

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