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Erschienen in: Journal of Nephrology 2/2019

01.04.2019 | Review

Myeloma light chain cast nephropathy, a review

verfasst von: Insara Jaffer Sathick, Maria Eleni Drosou, Nelson Leung

Erschienen in: Journal of Nephrology | Ausgabe 2/2019

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Abstract

Multiple Myeloma is a plasma cell proliferative disorder that commonly involves the kidney. Renal impairment is a serious complication during the course of the disease that is associated with increased morbidity and mortality. Light chain cast nephropathy is the predominant pattern of renal injury in Multiple Myeloma. This review article focuses on the pathophysiology and diagnostic approach of myeloma cast nephropathy. The management of precipitating factors as well as anti-plasma cell treatment modalities in the context of renal impairment are also discussed.
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Metadaten
Titel
Myeloma light chain cast nephropathy, a review
verfasst von
Insara Jaffer Sathick
Maria Eleni Drosou
Nelson Leung
Publikationsdatum
01.04.2019
Verlag
Springer International Publishing
Erschienen in
Journal of Nephrology / Ausgabe 2/2019
Print ISSN: 1121-8428
Elektronische ISSN: 1724-6059
DOI
https://doi.org/10.1007/s40620-018-0492-4

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