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Social Psychiatry and Psychiatric Epidemiology

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01.06.2007 | ORIGINAL PAPER

Neighbourhood variation in the incidence of psychotic disorders in Southeast London

verfasst von: James B. Kirkbride, Paul Fearon, Craig Morgan, Paola Dazzan, Kevin Morgan, Robin M. Murray, Peter B. Jones

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 6/2007

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Abstract

Background

Urbanicity is a risk factor for schizophrenia, but it is unclear whether this risk is homogenous across urban areas.

Aims

To determine whether the incidence of psychotic disorders varied within an urban area, beyond variation attributable to individual-level characteristics.

Methods

All incident cases of ICD-10 psychoses from a large, 2-year, epidemiological study of first-episode psychoses in Southeast London were identified. Incidence rates for 33 wards were standardised for age, sex and ethnicity. Bayesian models produced accurate relative risk estimates that were then mapped.

Results

295 cases were identified during 565,000 person-years of follow-up. We observed significant heterogeneity in relative risks for broad and non-affective psychoses (schizophrenia), but not for affective psychoses. Highest risks were observed in contiguous wards.

Conclusions

Neighbourhood variation in the incidence of non-affective psychoses could not be explained by individual-level risk, implicating neighbourhood-level socioenvironmental factors in their aetiology. The findings are consistent with classical sociological models of mental disorders.

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Titel: Neighbourhood variation in the incidence of psychotic disorders in Southeast London
verfasst von: James B. Kirkbride
Paul Fearon
Craig Morgan
Paola Dazzan
Kevin Morgan
Robin M. Murray
Peter B. Jones
Publikationsdatum: 01.06.2007
Verlag: D. Steinkopff-Verlag
Erschienen in: Social Psychiatry and Psychiatric Epidemiology / Ausgabe 6/2007
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI: https://doi.org/10.1007/s00127-007-0193-0

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Abstract

Background

Aims

Methods

Results

Conclusions

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