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Erschienen in: Current Neurology and Neuroscience Reports 7/2021

01.07.2021 | Neurology of Systemic Diseases (J. Biller, Section Editor)

Neurologic Complications of Poverty: the Associations Between Poverty as a Social Determinant of Health and Adverse Neurologic Outcomes

verfasst von: Monica Maalouf, Maureen Fearon, Mary Clare Lipa, Hannah Chow- Johnson, Linda Tayeh, Daniel Lipa

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 7/2021

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Abstract

Purpose of Review

Increasing attention has been paid in recent decades to social determinants of health as a risk factor for disease development and disease severity. While traditionally heart disease, family history, lipid profile, and tobacco use have all been associated with increased risk of neurological disease, numerous studies now show that the influence of poverty may be just as strong a risk factor. This study summarizes the recent literature on poverty as it contributes to neurological disease.

Recent Findings

Children growing up in poverty have increased risk for cognitive deficits and behavioral disorders as reported by Noble et al. (Dev Sci. 9(6):642–54, 2006) and Farah et al. (Brain Res. 1110(1):166–74, 2006) as well as worse outcomes when it comes to epilepsy management and disease course as discussed by Camfield et al. (Epilepsia. 57(11):1826–33, 2016). In adulthood, as the number of social determinants of health increases, the incidence of stroke and severe stroke increases significantly as reported by Reshetnyak et al. (Stroke. 51:2445–53, 2020) as does exposure to neurologically significant infectious diseases and incidence of dementia as reported by Sumilo et al. (Rev Med Virol. 18(2):81–95, 2008) and Zuelsdorff et al. (Alzheimer’s Dement. 6(1):e12039, 2020).

Summary

Social determinants of health including poverty should be considered a risk factor for disease. More attention is needed from clinicians as well as from a public health perspective to address this disparity.
Literatur
3.••
Zurück zum Zitat Reshetnyak E, Ntamatungiro M, Pinheiro LC, Howard VJ, Carson AP, Martin KD, et al. Impact of multiple social determinants of health on incident stroke. Stroke. 2020;51:2445–53. https://doi.org/10.1161/STROKEAHA.120.028530Excellent analysis of the impact of social determinants of health on stroke incidence and severity. This study looked at over 27,000 participants and specifically examined the impact of social determinant of health (SDOH) on stroke incidence. 10 SDOH were examined related to influences from economic, educational, social and health care contexts. Increase in the number of SDOH were independently associated with higher incident stroke risk in adults aged <75 years of age. Reshetnyak E, Ntamatungiro M, Pinheiro LC, Howard VJ, Carson AP, Martin KD, et al. Impact of multiple social determinants of health on incident stroke. Stroke. 2020;51:2445–53. https://​doi.​org/​10.​1161/​STROKEAHA.​120.​028530Excellent analysis of the impact of social determinants of health on stroke incidence and severity. This study looked at over 27,000 participants and specifically examined the impact of social determinant of health (SDOH) on stroke incidence. 10 SDOH were examined related to influences from economic, educational, social and health care contexts. Increase in the number of SDOH were independently associated with higher incident stroke risk in adults aged <75 years of age.
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Zurück zum Zitat Kim DJ, Davis EP, Sandman CA, Glynn L, Sporns O, O’Donnell BF, et al. Childhood poverty and the organization of structural brain connectome. Neuroimage. 2019;184:409–16. https://doi.org/10.1016/j.neuroimage.2018.09.041Excellent investigation of associations between the socioeconomic disparities and structural brain network organization in children. This study investigated associations between the socioeconomic disparities and structural brain network organization in children. Results showed that poverty was associated with increased network inefficiency in multiple cortical regions suggesting that childhood poverty may result in wide-spread neurologic disruptions, particularly at the lowest levels of socioeconomic disparity. Kim DJ, Davis EP, Sandman CA, Glynn L, Sporns O, O’Donnell BF, et al. Childhood poverty and the organization of structural brain connectome. Neuroimage. 2019;184:409–16. https://​doi.​org/​10.​1016/​j.​neuroimage.​2018.​09.​041Excellent investigation of associations between the socioeconomic disparities and structural brain network organization in children. This study investigated associations between the socioeconomic disparities and structural brain network organization in children. Results showed that poverty was associated with increased network inefficiency in multiple cortical regions suggesting that childhood poverty may result in wide-spread neurologic disruptions, particularly at the lowest levels of socioeconomic disparity.
11.••
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Zurück zum Zitat Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A. Individual and area-based socioeconomic factors associated with dementia incidence in England: evidence from a 12-year follow-up in the English longitudinal study of ageing. JAMA Psychiatry. 2018;75(7):723–32. https://doi.org/10.1001/jamapsychiatry.2018.1012Large-scale population analysis demonstrating that risk of dementia correlates with socioeconomic status. This study examined data from the English Longitudinal Study of Ageing, a prospective cohort study representative of the English population. Researchers demonstrated that the hazard of developing dementia was significantly higher for individuals in the lowest socioeconomic quintiles when compared to the highest quintile when controlling for other variables. Cadar D, Lassale C, Davies H, Llewellyn DJ, Batty GD, Steptoe A. Individual and area-based socioeconomic factors associated with dementia incidence in England: evidence from a 12-year follow-up in the English longitudinal study of ageing. JAMA Psychiatry. 2018;75(7):723–32. https://​doi.​org/​10.​1001/​jamapsychiatry.​2018.​1012Large-scale population analysis demonstrating that risk of dementia correlates with socioeconomic status. This study examined data from the English Longitudinal Study of Ageing, a prospective cohort study representative of the English population. Researchers demonstrated that the hazard of developing dementia was significantly higher for individuals in the lowest socioeconomic quintiles when compared to the highest quintile when controlling for other variables.
Metadaten
Titel
Neurologic Complications of Poverty: the Associations Between Poverty as a Social Determinant of Health and Adverse Neurologic Outcomes
verfasst von
Monica Maalouf
Maureen Fearon
Mary Clare Lipa
Hannah Chow- Johnson
Linda Tayeh
Daniel Lipa
Publikationsdatum
01.07.2021
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 7/2021
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-021-01116-z

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