Skip to main content
Erschienen in: Pediatric Radiology 9/2015

01.08.2015 | Original Article

Normal values of spleen stiffness in healthy children assessed by acoustic radiation force impulse imaging (ARFI): comparison between two ultrasound transducers

verfasst von: Teresa Cañas, Teresa Fontanilla, María Miralles, Araceli Maciá, Ana Malalana, Enriqueta Román

Erschienen in: Pediatric Radiology | Ausgabe 9/2015

Einloggen, um Zugang zu erhalten

Abstract

Background

Portal hypertension, a major complication of hepatic fibrosis, can affect the stiffness of the spleen.

Objective

To suggest normal values of spleen stiffness determined by acoustic radiation force impulse imaging in healthy children and to compare measurements using two different US probes.

Materials and methods

In a prospective study, 60 healthy children between 1 day and 14 years of age were assigned to four age groups with 15 children in each. Measurements were performed using two transducers (convex 4C1 and linear 9L4), and 10 measurements were obtained in each child, 5 with each probe.

Results

The mean splenic shear wave velocities were 2.17 m/s (SD 0.35, 95% CI 2.08–2.26) with the 4C1 probe and 2.15 m/s (SD 0.23, 95% CI 2.09–2.21) with the 9L4 probe (not significant).

Conclusion

We found normal values for spleen stiffness with no difference in the mean values obtained using two types of US transducers, but with higher variability using a convex compared to a linear transducer.
Literatur
1.
Zurück zum Zitat Rifai K, Cornberg J, Bahr M et al (2011) ARFI elastography of the spleen is inferior to liver elastography for detection of portal hypertension. Ultraschall Med 32:24–30CrossRef Rifai K, Cornberg J, Bahr M et al (2011) ARFI elastography of the spleen is inferior to liver elastography for detection of portal hypertension. Ultraschall Med 32:24–30CrossRef
2.
Zurück zum Zitat Grgurevic I, Cikara I, Horvat J et al (2011) Noninvasive assessment of liver fibrosis with acoustic radiation force imaging: increased liver and splenic stiffness in patients with liver fibrosis and cirrhosis. Ultraschall Med 32:160–166PubMedCrossRef Grgurevic I, Cikara I, Horvat J et al (2011) Noninvasive assessment of liver fibrosis with acoustic radiation force imaging: increased liver and splenic stiffness in patients with liver fibrosis and cirrhosis. Ultraschall Med 32:160–166PubMedCrossRef
3.
Zurück zum Zitat Sporea I, Sirli R, Bota S et al (2011) Is ARFI elastography reliable for predicting fibrosis severity in chronic HCV hepatitis? World J Radiol 3:188–193PubMedCentralPubMedCrossRef Sporea I, Sirli R, Bota S et al (2011) Is ARFI elastography reliable for predicting fibrosis severity in chronic HCV hepatitis? World J Radiol 3:188–193PubMedCentralPubMedCrossRef
4.
Zurück zum Zitat Friedrich-Rust M, Nierhoff J, Lupsor M et al (2012) Performance of acoustic radiation force impulse imaging for the staging of liver fibrosis: a pooled meta-analysis. J Viral Hepat 19:212–219CrossRef Friedrich-Rust M, Nierhoff J, Lupsor M et al (2012) Performance of acoustic radiation force impulse imaging for the staging of liver fibrosis: a pooled meta-analysis. J Viral Hepat 19:212–219CrossRef
5.
Zurück zum Zitat Rizzo L, Calvaruso V, Cacopardo B et al (2011) Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatitis C. Am J Gastroenterol 106:2112–2120PubMedCrossRef Rizzo L, Calvaruso V, Cacopardo B et al (2011) Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatitis C. Am J Gastroenterol 106:2112–2120PubMedCrossRef
6.
Zurück zum Zitat Noruegas MJ, Matos H, Goncalves I et al (2012) Acoustic radiation force impulse-imaging in the assessment of liver fibrosis in children. Pediatr Radiol 42:201–204PubMedCrossRef Noruegas MJ, Matos H, Goncalves I et al (2012) Acoustic radiation force impulse-imaging in the assessment of liver fibrosis in children. Pediatr Radiol 42:201–204PubMedCrossRef
7.
Zurück zum Zitat Marginean CO, Marginean C (2012) Elastographic assessment of liver fibrosis in children: a prospective single center experience. Eur J Radiol 81:e870–e874PubMedCrossRef Marginean CO, Marginean C (2012) Elastographic assessment of liver fibrosis in children: a prospective single center experience. Eur J Radiol 81:e870–e874PubMedCrossRef
8.
Zurück zum Zitat Li Y, Qian L, He W (2009) A study on the relationship between liver fibrosis staging and spleen volume by computed tomography in patients with chronic hepatitis B. Chin J Misdiagnostics 9:7561–7562 Li Y, Qian L, He W (2009) A study on the relationship between liver fibrosis staging and spleen volume by computed tomography in patients with chronic hepatitis B. Chin J Misdiagnostics 9:7561–7562
9.
Zurück zum Zitat Bota S, Sporea I, Sirli R et al (2010) Spleen assessment by acoustic radiation force impulse elastography (ARFI) for prediction of liver cirrhosis and portal hypertension. Med Ultrason 12:213–217PubMed Bota S, Sporea I, Sirli R et al (2010) Spleen assessment by acoustic radiation force impulse elastography (ARFI) for prediction of liver cirrhosis and portal hypertension. Med Ultrason 12:213–217PubMed
10.
Zurück zum Zitat Bota S, Sporea I, Sirli R et al (2012) Can ARFI elastography predict the presence of significant esophageal varices in newly diagnosed cirrhotic patients? Ann Hepatol 11:519–525PubMed Bota S, Sporea I, Sirli R et al (2012) Can ARFI elastography predict the presence of significant esophageal varices in newly diagnosed cirrhotic patients? Ann Hepatol 11:519–525PubMed
11.
Zurück zum Zitat Furuichi Y, Moriyasu F, Taira J et al (2012) Noninvasive diagnostic method for idiopathic portal hypertension based on measurements of liver and spleen stiffness by ARFI elastography. J Gastroenterol 48:1061–1068PubMedCrossRef Furuichi Y, Moriyasu F, Taira J et al (2012) Noninvasive diagnostic method for idiopathic portal hypertension based on measurements of liver and spleen stiffness by ARFI elastography. J Gastroenterol 48:1061–1068PubMedCrossRef
12.
Zurück zum Zitat Chen S, Li Y, Lai H et al (2012) Noninvasive assessment of liver fibrosis via spleen stiffness measurement using acoustic radiation force impulse sonoelastography in patients with chronic hepatitis B or C. J Viral Hepat 19:654–663PubMedCrossRef Chen S, Li Y, Lai H et al (2012) Noninvasive assessment of liver fibrosis via spleen stiffness measurement using acoustic radiation force impulse sonoelastography in patients with chronic hepatitis B or C. J Viral Hepat 19:654–663PubMedCrossRef
13.
Zurück zum Zitat Ye X, Ran H, Cheng J et al (2012) Liver and spleen stiffness measured by acoustic radiation force impulse elastography for noninvasive assessment of liver fibrosis and esophageal varices in patients with chronic hepatitis B. J Ultrasound Med 31:1245–1253PubMed Ye X, Ran H, Cheng J et al (2012) Liver and spleen stiffness measured by acoustic radiation force impulse elastography for noninvasive assessment of liver fibrosis and esophageal varices in patients with chronic hepatitis B. J Ultrasound Med 31:1245–1253PubMed
14.
Zurück zum Zitat Lee M-J, Kim MJ, Han KH et al (2013) Age-related changes in liver, kidney, and spleen stiffness in healthy children measured with acoustic radiation force impulse imaging. Eur J Radiol 82:290–294CrossRef Lee M-J, Kim MJ, Han KH et al (2013) Age-related changes in liver, kidney, and spleen stiffness in healthy children measured with acoustic radiation force impulse imaging. Eur J Radiol 82:290–294CrossRef
16.
Zurück zum Zitat Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMedCrossRef Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310PubMedCrossRef
17.
Zurück zum Zitat Takahashi H, Ono N, Eguchi Y et al (2010) Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study. Liver Int 30:538–545PubMedCrossRef Takahashi H, Ono N, Eguchi Y et al (2010) Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study. Liver Int 30:538–545PubMedCrossRef
18.
Zurück zum Zitat Sirli R, Bota S, Sporea I et al (2013) Liver stiffness measurements by means of supersonic shear imaging in patients without known liver pathology. Ultrasound Med Biol 8:1362–1367CrossRef Sirli R, Bota S, Sporea I et al (2013) Liver stiffness measurements by means of supersonic shear imaging in patients without known liver pathology. Ultrasound Med Biol 8:1362–1367CrossRef
19.
Zurück zum Zitat Pariente D, Franchi-Abella S (2010) Paediatric chronic liver diseases: how to investigate and follow up? Role of imaging in the diagnosis of fibrosis. Pediatr Radiol 40:906–919PubMedCrossRef Pariente D, Franchi-Abella S (2010) Paediatric chronic liver diseases: how to investigate and follow up? Role of imaging in the diagnosis of fibrosis. Pediatr Radiol 40:906–919PubMedCrossRef
20.
Zurück zum Zitat Ma JJ, Ding H, Mao F et al (2014) Assessment of liver fibrosis with elastography point quantification technique in chronic hepatitis B virus patients: a comparison with liver pathological results. J Gastroenterol Hepatol 29:814–819PubMedCrossRef Ma JJ, Ding H, Mao F et al (2014) Assessment of liver fibrosis with elastography point quantification technique in chronic hepatitis B virus patients: a comparison with liver pathological results. J Gastroenterol Hepatol 29:814–819PubMedCrossRef
21.
Zurück zum Zitat Chongsrisawat V, Vejapipat P, Siripon NB (2011) Transient elastography for predicting esophageal/gastric varices in children with biliary atresia. BMC Gastroenterol 18:41CrossRef Chongsrisawat V, Vejapipat P, Siripon NB (2011) Transient elastography for predicting esophageal/gastric varices in children with biliary atresia. BMC Gastroenterol 18:41CrossRef
22.
Zurück zum Zitat Gallotti A, D’Onofrio M, Pozzi Mucelli R (2010) Acoustic radiation force impulse-imaging (ARFI) technique in ultrasound with virtual touch tissue quantification of the upper abdomen. Radiol Med 115:889–897PubMedCrossRef Gallotti A, D’Onofrio M, Pozzi Mucelli R (2010) Acoustic radiation force impulse-imaging (ARFI) technique in ultrasound with virtual touch tissue quantification of the upper abdomen. Radiol Med 115:889–897PubMedCrossRef
23.
Zurück zum Zitat Fontanilla T, Canas T, Macia A et al (2014) Normal values of liver shear wave velocity in healthy children assessed by acoustic radiation force impulse imaging using a convex probe and a linear probe. Ultrasound Med Biol 40:470–477PubMedCrossRef Fontanilla T, Canas T, Macia A et al (2014) Normal values of liver shear wave velocity in healthy children assessed by acoustic radiation force impulse imaging using a convex probe and a linear probe. Ultrasound Med Biol 40:470–477PubMedCrossRef
24.
Zurück zum Zitat Mannelli L, Godfrey E, Joubert I et al (2010) MR elastography: spleen stiffness measurements in healthy volunteers — preliminary experience. AJR Am J Roentgenol 195:387–392PubMedCrossRef Mannelli L, Godfrey E, Joubert I et al (2010) MR elastography: spleen stiffness measurements in healthy volunteers — preliminary experience. AJR Am J Roentgenol 195:387–392PubMedCrossRef
25.
Zurück zum Zitat Hanquinet S, Courvoisier D, Kanavaki A et al (2013) Acoustic radiation force impulse imaging — normal values of liver stiffness in healthy children. Pediatr Radiol 43:539–544PubMedCrossRef Hanquinet S, Courvoisier D, Kanavaki A et al (2013) Acoustic radiation force impulse imaging — normal values of liver stiffness in healthy children. Pediatr Radiol 43:539–544PubMedCrossRef
Metadaten
Titel
Normal values of spleen stiffness in healthy children assessed by acoustic radiation force impulse imaging (ARFI): comparison between two ultrasound transducers
verfasst von
Teresa Cañas
Teresa Fontanilla
María Miralles
Araceli Maciá
Ana Malalana
Enriqueta Román
Publikationsdatum
01.08.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 9/2015
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-015-3306-z

Weitere Artikel der Ausgabe 9/2015

Pediatric Radiology 9/2015 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.