Skip to main content
Erschienen in: Obesity Surgery 3/2016

01.03.2016 | Review Article

Obstructive Sleep Apnea and Smoking as a Risk Factor for Venous Thromboembolism Events: Review of the Literature on the Common Pathophysiological Mechanisms

verfasst von: Eric Deflandre, Stephanie Degey, Natacha Opsomer, Jean-Francois Brichant, Jean Joris

Erschienen in: Obesity Surgery | Ausgabe 3/2016

Einloggen, um Zugang zu erhalten

Abstract

Venous thromboembolism events (VTE) are a common and preventable cause of postoperative complications. Interestingly, smoking and obstructive sleep apnea syndrome (OSA) affecting a large part of our population (and especially obese patients) are two underestimated predisposing factors of VTE. Many coagulation disorders favoring thromboembolism have been identified in the case of OSA and smoking and are reviewed in this article. They can be divided into two entities: endothelial dysfunction and hemostasis disorders. Interestingly OSA and smoking share common pathways to the prothrombotic state. The interactions with others comorbidities will also be discussed. This article provides pathophysiological mechanisms of the increased risk of thromboembolism in OSA patients and smokers, which should help manage these patients more adequately during the perioperative period.
Literatur
1.
Zurück zum Zitat Gould MK, Garcia DA, Wren SM, et al. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e227S–77.PubMedCentralCrossRefPubMed Gould MK, Garcia DA, Wren SM, et al. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e227S–77.PubMedCentralCrossRefPubMed
3.
Zurück zum Zitat Kahn SR, Lim W, Dunn AS, et al. Prevention of VTE in nonsurgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e195S–226.PubMedCentralCrossRefPubMed Kahn SR, Lim W, Dunn AS, et al. Prevention of VTE in nonsurgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e195S–226.PubMedCentralCrossRefPubMed
5.
Zurück zum Zitat Garvey JF, Pengo MF, Drakatos P, et al. Epidemiological aspects of obstructive sleep apnea. J Thorac Dis. 2015;7:920–9.PubMedCentralPubMed Garvey JF, Pengo MF, Drakatos P, et al. Epidemiological aspects of obstructive sleep apnea. J Thorac Dis. 2015;7:920–9.PubMedCentralPubMed
7.
Zurück zum Zitat Bosanquet JP, Bade BC, Zia MF, et al. Patients with venous thromboembolism appear to have higher prevalence of obstructive sleep apnea than the general population. Clin Appl Thromb Hemost. 2011;17:E119–24.CrossRefPubMed Bosanquet JP, Bade BC, Zia MF, et al. Patients with venous thromboembolism appear to have higher prevalence of obstructive sleep apnea than the general population. Clin Appl Thromb Hemost. 2011;17:E119–24.CrossRefPubMed
8.
Zurück zum Zitat Horlander KT, Mannino DM, Leeper KV. Pulmonary embolism mortality in the United States, 1979–1998: an analysis using multiple-cause mortality data. Arch Intern Med. 2003;163:1711–7.CrossRefPubMed Horlander KT, Mannino DM, Leeper KV. Pulmonary embolism mortality in the United States, 1979–1998: an analysis using multiple-cause mortality data. Arch Intern Med. 2003;163:1711–7.CrossRefPubMed
9.
Zurück zum Zitat Falck-Ytter Y, Francis CW, Johanson NA, et al. Prevention of VTE in orthopedic surgery patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e278S–325.PubMedCentralCrossRefPubMed Falck-Ytter Y, Francis CW, Johanson NA, et al. Prevention of VTE in orthopedic surgery patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e278S–325.PubMedCentralCrossRefPubMed
10.
Zurück zum Zitat Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol. 2004;43:1731–7.CrossRefPubMed Ambrose JA, Barua RS. The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol. 2004;43:1731–7.CrossRefPubMed
11.
Zurück zum Zitat Law MR, Morris JK, Wald NJ. Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence. BMJ. 1997;315:973–80.PubMedCentralCrossRefPubMed Law MR, Morris JK, Wald NJ. Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence. BMJ. 1997;315:973–80.PubMedCentralCrossRefPubMed
12.
Zurück zum Zitat Cheng YJ, Liu ZH, Yao FJ, et al. Current and former smoking and risk for venous thromboembolism: a systematic review and meta-analysis. PLoS Med. 2013;10:e1001515.PubMedCentralCrossRefPubMed Cheng YJ, Liu ZH, Yao FJ, et al. Current and former smoking and risk for venous thromboembolism: a systematic review and meta-analysis. PLoS Med. 2013;10:e1001515.PubMedCentralCrossRefPubMed
13.
Zurück zum Zitat Budhiraja R, Parthasarathy S, Quan SF. Endothelial dysfunction in obstructive sleep apnea. J Clin Sleep Med. 2007;3:409–15.PubMedCentralPubMed Budhiraja R, Parthasarathy S, Quan SF. Endothelial dysfunction in obstructive sleep apnea. J Clin Sleep Med. 2007;3:409–15.PubMedCentralPubMed
15.
Zurück zum Zitat Nieto FJ, Herrington DM, Redline S, et al. Sleep apnea and markers of vascular endothelial function in a large community sample of older adults. Am J Respir Crit Care Med. 2004;169:354–60.CrossRefPubMed Nieto FJ, Herrington DM, Redline S, et al. Sleep apnea and markers of vascular endothelial function in a large community sample of older adults. Am J Respir Crit Care Med. 2004;169:354–60.CrossRefPubMed
16.
Zurück zum Zitat Korcarz CE, Gepner AD, Peppard PE, et al. The effects of sleep-disordered breathing on arterial stiffness are modulated by age. Sleep. 2010;33:1081–5.PubMedCentralPubMed Korcarz CE, Gepner AD, Peppard PE, et al. The effects of sleep-disordered breathing on arterial stiffness are modulated by age. Sleep. 2010;33:1081–5.PubMedCentralPubMed
17.
Zurück zum Zitat Ip MS, Tse HF, Lam B, et al. Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med. 2004;169:348–53.CrossRefPubMed Ip MS, Tse HF, Lam B, et al. Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med. 2004;169:348–53.CrossRefPubMed
18.
Zurück zum Zitat Namtvedt SK, Hisdal J, Randby A, Agewall S, Stranden E, Somers VK, Røsjø H, Omland T. Impaired endothelial function in persons with obstructive sleep apnoea: impact of obesity. Heart. 2012. Namtvedt SK, Hisdal J, Randby A, Agewall S, Stranden E, Somers VK, Røsjø H, Omland T. Impaired endothelial function in persons with obstructive sleep apnoea: impact of obesity. Heart. 2012.
19.
Zurück zum Zitat Wannamethee SG, Lowe GD, Shaper AG, et al. Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. Eur Heart J. 2005;26:1765–73.CrossRefPubMed Wannamethee SG, Lowe GD, Shaper AG, et al. Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. Eur Heart J. 2005;26:1765–73.CrossRefPubMed
20.
Zurück zum Zitat Blitzer ML, Loh E, Roddy MA, et al. Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans. J Am Coll Cardiol. 1996;28:591–6.CrossRefPubMed Blitzer ML, Loh E, Roddy MA, et al. Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans. J Am Coll Cardiol. 1996;28:591–6.CrossRefPubMed
22.
23.
Zurück zum Zitat Deanfield J, Donald A, Ferri C, et al. Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. J Hypertens. 2005;23:7–17.CrossRefPubMed Deanfield J, Donald A, Ferri C, et al. Endothelial function and dysfunction. Part I: methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. J Hypertens. 2005;23:7–17.CrossRefPubMed
24.
Zurück zum Zitat Jelic S, Padeletti M, Kawut SM, et al. Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation. 2008;117:2270–8.PubMedCentralCrossRefPubMed Jelic S, Padeletti M, Kawut SM, et al. Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation. 2008;117:2270–8.PubMedCentralCrossRefPubMed
25.
Zurück zum Zitat Kugiyama K, Yasue H, Ohgushi M, et al. Deficiency in nitric oxide bioactivity in epicardial coronary arteries of cigarette smokers. J Am Coll Cardiol. 1996;28:1161–7.CrossRefPubMed Kugiyama K, Yasue H, Ohgushi M, et al. Deficiency in nitric oxide bioactivity in epicardial coronary arteries of cigarette smokers. J Am Coll Cardiol. 1996;28:1161–7.CrossRefPubMed
26.
Zurück zum Zitat Buchner NJ, Quack I, Woznowski M, et al. Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy. Respiration. 2011;82:409–17.CrossRefPubMed Buchner NJ, Quack I, Woznowski M, et al. Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy. Respiration. 2011;82:409–17.CrossRefPubMed
27.
Zurück zum Zitat Yanbaeva DG, Dentener MA, Creutzberg EC, et al. Systemic effects of smoking. CHEST J. 2007;131:1557–66.CrossRef Yanbaeva DG, Dentener MA, Creutzberg EC, et al. Systemic effects of smoking. CHEST J. 2007;131:1557–66.CrossRef
28.
Zurück zum Zitat Barua RS, Ambrose JA. Mechanisms of coronary thrombosis in cigarette smoke exposure. Arterioscler Thromb Vasc Biol. 2013;33:1460–7.CrossRefPubMed Barua RS, Ambrose JA. Mechanisms of coronary thrombosis in cigarette smoke exposure. Arterioscler Thromb Vasc Biol. 2013;33:1460–7.CrossRefPubMed
29.
Zurück zum Zitat Phillips BG, Hisel TM, Kato M, et al. Recent weight gain in patients with newly diagnosed obstructive sleep apnea. J Hypertens. 1999;17:1297–300.CrossRefPubMed Phillips BG, Hisel TM, Kato M, et al. Recent weight gain in patients with newly diagnosed obstructive sleep apnea. J Hypertens. 1999;17:1297–300.CrossRefPubMed
30.
Zurück zum Zitat Rahman MM, Elmi S, Chang TK, et al. Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release. Vasc Pharmacol. 2007;46:35–42.CrossRef Rahman MM, Elmi S, Chang TK, et al. Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release. Vasc Pharmacol. 2007;46:35–42.CrossRef
31.
Zurück zum Zitat Moller DS, Lind P, Strunge B, et al. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea. Am J Hypertens. 2003;16:274–80.CrossRefPubMed Moller DS, Lind P, Strunge B, et al. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea. Am J Hypertens. 2003;16:274–80.CrossRefPubMed
32.
Zurück zum Zitat Ohga E, Nagase T, Tomita T, et al. Increased levels of circulating ICAM-1, VCAM-1, and L-selectin in obstructive sleep apnea syndrome. J Appl Physiol (Bethesda, Md: 1985). 1999;87:10–4. Ohga E, Nagase T, Tomita T, et al. Increased levels of circulating ICAM-1, VCAM-1, and L-selectin in obstructive sleep apnea syndrome. J Appl Physiol (Bethesda, Md: 1985). 1999;87:10–4.
33.
Zurück zum Zitat El-Solh AA, Mador MJ, Sikka P, et al. Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea. Chest. 2002;121:1541–7.CrossRefPubMed El-Solh AA, Mador MJ, Sikka P, et al. Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea. Chest. 2002;121:1541–7.CrossRefPubMed
34.
Zurück zum Zitat Mazzone A, Cusa C, Mazzucchelli I, et al. Cigarette smoking and hypertension influence nitric oxide release and plasma levels of adhesion molecules. Clin Chem Lab Med CCLM/FESCC. 2001;39:822–6. Mazzone A, Cusa C, Mazzucchelli I, et al. Cigarette smoking and hypertension influence nitric oxide release and plasma levels of adhesion molecules. Clin Chem Lab Med CCLM/FESCC. 2001;39:822–6.
35.
Zurück zum Zitat Adams MR, Jessup W, Celermajer DS. Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells: reversibility with oral L-arginine but not vitamin C. J Am Coll Cardiol. 1997;29:491–7.CrossRefPubMed Adams MR, Jessup W, Celermajer DS. Cigarette smoking is associated with increased human monocyte adhesion to endothelial cells: reversibility with oral L-arginine but not vitamin C. J Am Coll Cardiol. 1997;29:491–7.CrossRefPubMed
36.
Zurück zum Zitat Dyugovskaya L, Lavie P, Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med. 2002;165:934–9.CrossRefPubMed Dyugovskaya L, Lavie P, Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med. 2002;165:934–9.CrossRefPubMed
37.
Zurück zum Zitat Oudijk EJ, Lammers JW, Koenderman L. Systemic inflammation in chronic obstructive pulmonary disease. Eur Respir J Suppl. 2003;46:5s–13.CrossRefPubMed Oudijk EJ, Lammers JW, Koenderman L. Systemic inflammation in chronic obstructive pulmonary disease. Eur Respir J Suppl. 2003;46:5s–13.CrossRefPubMed
38.
Zurück zum Zitat Dyugovskaya L, Polyakov A, Lavie P, et al. Delayed neutrophil apoptosis in patients with sleep apnea. Am J Respir Crit Care Med. 2008;177:544–54.CrossRefPubMed Dyugovskaya L, Polyakov A, Lavie P, et al. Delayed neutrophil apoptosis in patients with sleep apnea. Am J Respir Crit Care Med. 2008;177:544–54.CrossRefPubMed
39.
Zurück zum Zitat Luc G, Bard JM, Juhan-Vague I, et al. C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study. Arterioscler Thromb Vasc Biol. 2003;23:1255–61.CrossRefPubMed Luc G, Bard JM, Juhan-Vague I, et al. C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study. Arterioscler Thromb Vasc Biol. 2003;23:1255–61.CrossRefPubMed
40.
Zurück zum Zitat Lavie L, Polotsky V. Cardiovascular aspects in obstructive sleep apnea syndrome--molecular issues, hypoxia and cytokine profiles. Respiration. 2009;78:361–70.CrossRefPubMed Lavie L, Polotsky V. Cardiovascular aspects in obstructive sleep apnea syndrome--molecular issues, hypoxia and cytokine profiles. Respiration. 2009;78:361–70.CrossRefPubMed
41.
Zurück zum Zitat Craig WY, Palomaki GE, Haddow JE. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data. BMJ. 1989;298:784–8.PubMedCentralCrossRefPubMed Craig WY, Palomaki GE, Haddow JE. Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data. BMJ. 1989;298:784–8.PubMedCentralCrossRefPubMed
42.
43.
Zurück zum Zitat Peppard PE, Young T, Palta M, et al. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA J Am Med Assoc. 2000;284:3015–21.CrossRef Peppard PE, Young T, Palta M, et al. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA J Am Med Assoc. 2000;284:3015–21.CrossRef
45.
Zurück zum Zitat Bouloumie A, Marumo T, Lafontan M, et al. Leptin induces oxidative stress in human endothelial cells. FASEB J Off Publ Fed Am Soc Exp Biol. 1999;13:1231–8. Bouloumie A, Marumo T, Lafontan M, et al. Leptin induces oxidative stress in human endothelial cells. FASEB J Off Publ Fed Am Soc Exp Biol. 1999;13:1231–8.
46.
Zurück zum Zitat Bouloumie A, Drexler HC, Lafontan M, et al. Leptin, the product of Ob gene, promotes angiogenesis. Circ Res. 1998;83:1059–66.CrossRefPubMed Bouloumie A, Drexler HC, Lafontan M, et al. Leptin, the product of Ob gene, promotes angiogenesis. Circ Res. 1998;83:1059–66.CrossRefPubMed
47.
Zurück zum Zitat Luo JD, Zhang GS, Chen MS. Leptin and cardiovascular diseases. Drug News Perspect. 2005;18:427–31.CrossRefPubMed Luo JD, Zhang GS, Chen MS. Leptin and cardiovascular diseases. Drug News Perspect. 2005;18:427–31.CrossRefPubMed
48.
Zurück zum Zitat Oda A, Taniguchi T, Yokoyama M. Leptin stimulates rat aortic smooth muscle cell proliferation and migration. Kobe J Med Sci. 2001;47:141–50.PubMed Oda A, Taniguchi T, Yokoyama M. Leptin stimulates rat aortic smooth muscle cell proliferation and migration. Kobe J Med Sci. 2001;47:141–50.PubMed
49.
Zurück zum Zitat Nishimura M, Izumiya Y, Higuchi A, et al. Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms. Circulation. 2008;117:216–23.CrossRefPubMed Nishimura M, Izumiya Y, Higuchi A, et al. Adiponectin prevents cerebral ischemic injury through endothelial nitric oxide synthase dependent mechanisms. Circulation. 2008;117:216–23.CrossRefPubMed
50.
Zurück zum Zitat Zhang XL, Yin KS, Wang H, et al. Serum adiponectin levels in adult male patients with obstructive sleep apnea hypopnea syndrome. Respiration. 2006;73:73–7.CrossRefPubMed Zhang XL, Yin KS, Wang H, et al. Serum adiponectin levels in adult male patients with obstructive sleep apnea hypopnea syndrome. Respiration. 2006;73:73–7.CrossRefPubMed
51.
Zurück zum Zitat Preckel D, von Kanel R. Regulation of hemostasis by the sympathetic nervous system: any contribution to coronary artery disease? Heartdrug Excell Cardiovasc Trials. 2004;4:123–30. Preckel D, von Kanel R. Regulation of hemostasis by the sympathetic nervous system: any contribution to coronary artery disease? Heartdrug Excell Cardiovasc Trials. 2004;4:123–30.
52.
Zurück zum Zitat Marrone O, Riccobono L, Salvaggio A, et al. Catecholamines and blood pressure in obstructive sleep apnea syndrome. Chest. 1993;103:722–7.CrossRefPubMed Marrone O, Riccobono L, Salvaggio A, et al. Catecholamines and blood pressure in obstructive sleep apnea syndrome. Chest. 1993;103:722–7.CrossRefPubMed
53.
Zurück zum Zitat Adamopoulos D, van de Borne P, Argacha JF. New insights into the sympathetic, endothelial and coronary effects of nicotine. Clin Exp Pharmacol Physiol. 2008;35:458–63.CrossRefPubMed Adamopoulos D, van de Borne P, Argacha JF. New insights into the sympathetic, endothelial and coronary effects of nicotine. Clin Exp Pharmacol Physiol. 2008;35:458–63.CrossRefPubMed
54.
Zurück zum Zitat Millar PJ, Murai H, Floras JS. Neurogenic retrograde arterial flow during obstructive sleep apnea: a novel mechanism for endothelial dysfunction? Hypertension. 2011. Millar PJ, Murai H, Floras JS. Neurogenic retrograde arterial flow during obstructive sleep apnea: a novel mechanism for endothelial dysfunction? Hypertension. 2011.
55.
Zurück zum Zitat Riha RL, Brander P, Vennelle M, et al. Tumour necrosis factor-alpha (−308) gene polymorphism in obstructive sleep apnoea-hypopnoea syndrome. Eur Respir J. 2005;26:673–8.CrossRefPubMed Riha RL, Brander P, Vennelle M, et al. Tumour necrosis factor-alpha (−308) gene polymorphism in obstructive sleep apnoea-hypopnoea syndrome. Eur Respir J. 2005;26:673–8.CrossRefPubMed
56.
Zurück zum Zitat Lin L, Finn L, Zhang J, et al. Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. Am J Respir Crit Care Med. 2004;170:1349–53.CrossRefPubMed Lin L, Finn L, Zhang J, et al. Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. Am J Respir Crit Care Med. 2004;170:1349–53.CrossRefPubMed
57.
Zurück zum Zitat Wang XL, Sim AS, Wang MX, et al. Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity. FEBS Lett. 2000;471:45–50.CrossRefPubMed Wang XL, Sim AS, Wang MX, et al. Genotype dependent and cigarette specific effects on endothelial nitric oxide synthase gene expression and enzyme activity. FEBS Lett. 2000;471:45–50.CrossRefPubMed
58.
Zurück zum Zitat Wang XL, Greco M, Sim AS, et al. Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. Atherosclerosis. 2002;162:391–7.CrossRefPubMed Wang XL, Greco M, Sim AS, et al. Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes. Atherosclerosis. 2002;162:391–7.CrossRefPubMed
59.
Zurück zum Zitat Wang XL, Raveendran M, Wang J. Genetic influence on cigarette-induced cardiovascular disease. Prog Cardiovasc Dis. 2003;45:361–82.CrossRefPubMed Wang XL, Raveendran M, Wang J. Genetic influence on cigarette-induced cardiovascular disease. Prog Cardiovasc Dis. 2003;45:361–82.CrossRefPubMed
60.
Zurück zum Zitat Bokinsky G, Miller M, Ault K, et al. Spontaneous platelet activation and aggregation during obstructive sleep apnea and its response to therapy with nasal continuous positive airway pressure. A preliminary investigation. Chest. 1995;108:625–30.CrossRefPubMed Bokinsky G, Miller M, Ault K, et al. Spontaneous platelet activation and aggregation during obstructive sleep apnea and its response to therapy with nasal continuous positive airway pressure. A preliminary investigation. Chest. 1995;108:625–30.CrossRefPubMed
61.
Zurück zum Zitat Fusegawa Y, Goto S, Handa S, et al. Platelet spontaneous aggregation in platelet-rich plasma is increased in habitual smokers. Thromb Res. 1999;93:271–8.CrossRefPubMed Fusegawa Y, Goto S, Handa S, et al. Platelet spontaneous aggregation in platelet-rich plasma is increased in habitual smokers. Thromb Res. 1999;93:271–8.CrossRefPubMed
62.
Zurück zum Zitat Takajo Y, Ikeda H, Haramaki N, et al. Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability. J Am Coll Cardiol. 2001;38:1320–7.CrossRefPubMed Takajo Y, Ikeda H, Haramaki N, et al. Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability. J Am Coll Cardiol. 2001;38:1320–7.CrossRefPubMed
63.
Zurück zum Zitat Freedman JE. Molecular regulation of platelet-dependent thrombosis. Circulation. 2005;112:2725–34.CrossRefPubMed Freedman JE. Molecular regulation of platelet-dependent thrombosis. Circulation. 2005;112:2725–34.CrossRefPubMed
64.
Zurück zum Zitat Sambola A, Osende J, Hathcock J, et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity. Circulation. 2003;107:973–7.CrossRefPubMed Sambola A, Osende J, Hathcock J, et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity. Circulation. 2003;107:973–7.CrossRefPubMed
65.
Zurück zum Zitat El Solh AA, Akinnusi ME, Berim IG, et al. Hemostatic implications of endothelial cell apoptosis in obstructive sleep apnea. Sleep Breath. 2008;12:331–7.CrossRefPubMed El Solh AA, Akinnusi ME, Berim IG, et al. Hemostatic implications of endothelial cell apoptosis in obstructive sleep apnea. Sleep Breath. 2008;12:331–7.CrossRefPubMed
66.
Zurück zum Zitat Barua RS, Ambrose JA, Saha DC, et al. Smoking is associated with altered endothelial-derived fibrinolytic and antithrombotic factors: an in vitro demonstration. Circulation. 2002;106:905–8.CrossRefPubMed Barua RS, Ambrose JA, Saha DC, et al. Smoking is associated with altered endothelial-derived fibrinolytic and antithrombotic factors: an in vitro demonstration. Circulation. 2002;106:905–8.CrossRefPubMed
67.
Zurück zum Zitat Dotevall A, Johansson S, Wilhelmsen L. Association between fibrinogen and other risk factors for cardiovascular disease in men and women. Results from the Goteborg MONICA survey 1985. Ann Epidemiol. 1994;4:369–74.CrossRefPubMed Dotevall A, Johansson S, Wilhelmsen L. Association between fibrinogen and other risk factors for cardiovascular disease in men and women. Results from the Goteborg MONICA survey 1985. Ann Epidemiol. 1994;4:369–74.CrossRefPubMed
68.
Zurück zum Zitat Wessendorf TE, Thilmann AF, Wang YM, et al. Fibrinogen levels and obstructive sleep apnea in ischemic stroke. Am J Respir Crit Care Med. 2000;162:2039–42.CrossRefPubMed Wessendorf TE, Thilmann AF, Wang YM, et al. Fibrinogen levels and obstructive sleep apnea in ischemic stroke. Am J Respir Crit Care Med. 2000;162:2039–42.CrossRefPubMed
69.
Zurück zum Zitat Chin K, Ohi M, Kita H, et al. Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome. Am J Respir Crit Care Med. 1996;153:1972–6.CrossRefPubMed Chin K, Ohi M, Kita H, et al. Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome. Am J Respir Crit Care Med. 1996;153:1972–6.CrossRefPubMed
70.
Zurück zum Zitat Shitrit D, Peled N, Shitrit AB, et al. An association between oxygen desaturation and D-dimer in patients with obstructive sleep apnea syndrome. Thromb Haemost. 2005;94:544–7.PubMed Shitrit D, Peled N, Shitrit AB, et al. An association between oxygen desaturation and D-dimer in patients with obstructive sleep apnea syndrome. Thromb Haemost. 2005;94:544–7.PubMed
71.
Zurück zum Zitat von Kanel R, Loredo JS, Ancoli-Israel S, et al. Association between polysomnographic measures of disrupted sleep and prothrombotic factors. Chest. 2007;131:733–9.CrossRef von Kanel R, Loredo JS, Ancoli-Israel S, et al. Association between polysomnographic measures of disrupted sleep and prothrombotic factors. Chest. 2007;131:733–9.CrossRef
72.
Zurück zum Zitat Robinson GV, Pepperell JCT, Segal HC, et al. Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials. Thorax. 2004;59:777–82.PubMedCentralCrossRefPubMed Robinson GV, Pepperell JCT, Segal HC, et al. Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials. Thorax. 2004;59:777–82.PubMedCentralCrossRefPubMed
73.
Zurück zum Zitat von Kanel R, Loredo JS, Powell FL, et al. Short-term isocapnic hypoxia and coagulation activation in patients with sleep apnea. Clin Hemorheol Microcirc. 2005;33:369–77. von Kanel R, Loredo JS, Powell FL, et al. Short-term isocapnic hypoxia and coagulation activation in patients with sleep apnea. Clin Hemorheol Microcirc. 2005;33:369–77.
74.
Zurück zum Zitat Barceló A, Piérola J, de la Peña M, et al. Day–night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea. Eur Respir J. 2012;39:913–8.CrossRefPubMed Barceló A, Piérola J, de la Peña M, et al. Day–night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea. Eur Respir J. 2012;39:913–8.CrossRefPubMed
75.
Zurück zum Zitat von Kanel R, Loredo JS, Ancoli-Israel S, et al. Association between sleep apnea severity and blood coagulability: treatment effects of nasal continuous positive airway pressure. Sleep Breath. 2006;10:139–46.CrossRef von Kanel R, Loredo JS, Ancoli-Israel S, et al. Association between sleep apnea severity and blood coagulability: treatment effects of nasal continuous positive airway pressure. Sleep Breath. 2006;10:139–46.CrossRef
76.
Zurück zum Zitat Simpson AJ, Gray RS, Moore NR, et al. The effects of chronic smoking on the fibrinolytic potential of plasma and platelets. Br J Haematol. 1997;97:208–13.CrossRefPubMed Simpson AJ, Gray RS, Moore NR, et al. The effects of chronic smoking on the fibrinolytic potential of plasma and platelets. Br J Haematol. 1997;97:208–13.CrossRefPubMed
77.
Zurück zum Zitat Newby DE, Wright RA, Labinjoh C, et al. Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction. Circulation. 1999;99:1411–5.CrossRefPubMed Newby DE, Wright RA, Labinjoh C, et al. Endothelial dysfunction, impaired endogenous fibrinolysis, and cigarette smoking: a mechanism for arterial thrombosis and myocardial infarction. Circulation. 1999;99:1411–5.CrossRefPubMed
78.
Zurück zum Zitat Lippi G, Mattiuzzi C, Franchini M. Sleep apnea and venous thromboembolism. A systematic review. Thromb Haemost. 2015;114:885–9.CrossRef Lippi G, Mattiuzzi C, Franchini M. Sleep apnea and venous thromboembolism. A systematic review. Thromb Haemost. 2015;114:885–9.CrossRef
79.
Zurück zum Zitat Peng YH, Liao WC, Chung WS, et al. Association between obstructive sleep apnea and deep vein thrombosis / pulmonary embolism: a population-based retrospective cohort study. Thromb Res. 2014;134:340–5.CrossRefPubMed Peng YH, Liao WC, Chung WS, et al. Association between obstructive sleep apnea and deep vein thrombosis / pulmonary embolism: a population-based retrospective cohort study. Thromb Res. 2014;134:340–5.CrossRefPubMed
80.
Zurück zum Zitat D’Apuzzo MR, Browne JA. Obstructive sleep apnea as a risk factor for postoperative complications after revision joint arthroplasty. J Arthroplast. 2012;27:95–8.CrossRef D’Apuzzo MR, Browne JA. Obstructive sleep apnea as a risk factor for postoperative complications after revision joint arthroplasty. J Arthroplast. 2012;27:95–8.CrossRef
81.
Zurück zum Zitat Sapala JA, Wood MH, Schuhknecht MP, et al. Fatal pulmonary embolism after bariatric operations for morbid obesity: a 24-year retrospective analysis. Obes Surg. 2003;13:819–25.CrossRefPubMed Sapala JA, Wood MH, Schuhknecht MP, et al. Fatal pulmonary embolism after bariatric operations for morbid obesity: a 24-year retrospective analysis. Obes Surg. 2003;13:819–25.CrossRefPubMed
82.
Zurück zum Zitat Louis JM, Mogos MF, Salemi JL, et al. Obstructive sleep apnea and severe maternal-infant morbidity/mortality in the United States, 1998–2009. Sleep. 2014;37:843–9.PubMedCentralPubMed Louis JM, Mogos MF, Salemi JL, et al. Obstructive sleep apnea and severe maternal-infant morbidity/mortality in the United States, 1998–2009. Sleep. 2014;37:843–9.PubMedCentralPubMed
83.
Zurück zum Zitat Mraovic B, Hipszer BR, Epstein RH, et al. Preadmission hyperglycemia is an independent risk factor for in-hospital symptomatic pulmonary embolism after major orthopedic surgery. J Arthroplast. 2010;25:64–70.CrossRef Mraovic B, Hipszer BR, Epstein RH, et al. Preadmission hyperglycemia is an independent risk factor for in-hospital symptomatic pulmonary embolism after major orthopedic surgery. J Arthroplast. 2010;25:64–70.CrossRef
84.
Zurück zum Zitat Memtsoudis S, Liu S, Ma Y, et al. Perioperative pulmonary outcomes in patients with sleep apnea after noncardiac surgery. Anesth Analg. 2011;112:113–21.CrossRefPubMed Memtsoudis S, Liu S, Ma Y, et al. Perioperative pulmonary outcomes in patients with sleep apnea after noncardiac surgery. Anesth Analg. 2011;112:113–21.CrossRefPubMed
85.
Zurück zum Zitat Hansson PO, Eriksson H, Welin L, et al. Smoking and abdominal obesity: risk factors for venous thromboembolism among middle-aged men: “the study of men born in 1913”. Arch Intern Med. 1999;159:1886–90.CrossRefPubMed Hansson PO, Eriksson H, Welin L, et al. Smoking and abdominal obesity: risk factors for venous thromboembolism among middle-aged men: “the study of men born in 1913”. Arch Intern Med. 1999;159:1886–90.CrossRefPubMed
86.
Zurück zum Zitat Zhang G, Xu X, Su W, et al. Smoking and risk of venous thromboembolism: a systematic review. Southeast Asian J Trop Med Publ Health. 2014;45:736–45. Zhang G, Xu X, Su W, et al. Smoking and risk of venous thromboembolism: a systematic review. Southeast Asian J Trop Med Publ Health. 2014;45:736–45.
87.
Zurück zum Zitat Hawn MT, Houston TK, Campagna EJ, et al. The attributable risk of smoking on surgical complications. Ann Surg. 2011;254:914–20.CrossRefPubMed Hawn MT, Houston TK, Campagna EJ, et al. The attributable risk of smoking on surgical complications. Ann Surg. 2011;254:914–20.CrossRefPubMed
88.
Zurück zum Zitat Krishnan V, Dixon-Williams S, Thornton JD. Where there is smoke…there is sleep apnea: exploring the relationship between smoking and sleep apnea. Chest. 2014;146:1673–80.PubMedCentralCrossRefPubMed Krishnan V, Dixon-Williams S, Thornton JD. Where there is smoke…there is sleep apnea: exploring the relationship between smoking and sleep apnea. Chest. 2014;146:1673–80.PubMedCentralCrossRefPubMed
89.
Zurück zum Zitat Tzischinsky O, Cohen A, Doveh E, et al. Screening for sleep disordered breathing among applicants for a professional driver’s license. J Occup Environ Med/Am Coll Occup Environ Med. 2012;54:1275–80.CrossRef Tzischinsky O, Cohen A, Doveh E, et al. Screening for sleep disordered breathing among applicants for a professional driver’s license. J Occup Environ Med/Am Coll Occup Environ Med. 2012;54:1275–80.CrossRef
90.
Zurück zum Zitat Wetter DW, Young TB, Bidwell TR, et al. Smoking as a risk factor for sleep-disordered breathing. Arch Intern Med. 1994;154:2219–24.CrossRefPubMed Wetter DW, Young TB, Bidwell TR, et al. Smoking as a risk factor for sleep-disordered breathing. Arch Intern Med. 1994;154:2219–24.CrossRefPubMed
91.
Zurück zum Zitat Varol Y, Anar C, Tuzel OE, et al. The impact of active and former smoking on the severity of obstructive sleep apnea. Sleep Breath. 2015;19(4):1279–84.CrossRefPubMed Varol Y, Anar C, Tuzel OE, et al. The impact of active and former smoking on the severity of obstructive sleep apnea. Sleep Breath. 2015;19(4):1279–84.CrossRefPubMed
92.
Zurück zum Zitat Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA. 2000;283:1829–36.CrossRefPubMed Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA. 2000;283:1829–36.CrossRefPubMed
93.
Zurück zum Zitat Samama CM, Godier A. Perioperative deep vein thrombosis prevention: what works, what does not work and does it improve outcome? Curr Opin Anaesthesiol. 2011;24:166–70.CrossRefPubMed Samama CM, Godier A. Perioperative deep vein thrombosis prevention: what works, what does not work and does it improve outcome? Curr Opin Anaesthesiol. 2011;24:166–70.CrossRefPubMed
94.
Zurück zum Zitat Guyatt GH, Eikelboom JW, Gould MK, et al. Approach to outcome measurement in the prevention of thrombosis in surgical and medical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e185S–94.PubMedCentralCrossRefPubMed Guyatt GH, Eikelboom JW, Gould MK, et al. Approach to outcome measurement in the prevention of thrombosis in surgical and medical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e185S–94.PubMedCentralCrossRefPubMed
95.
Zurück zum Zitat Deflandre E, Degey S, Bonhomme V, Donneau AF, Poirrier R, Brichant JF, Hans P. Preoperative adherence to continuous positive airway pressure among obstructive sleep apnea patients. Minerva Anestesiol. 2014. Deflandre E, Degey S, Bonhomme V, Donneau AF, Poirrier R, Brichant JF, Hans P. Preoperative adherence to continuous positive airway pressure among obstructive sleep apnea patients. Minerva Anestesiol. 2014.
96.
Zurück zum Zitat Deflandre E, Brichant JF, Bonhomme V. Obstructive sleep apnea and detection of non-adherence to CPAP in OSA: limits of the pre-anesthesia visit. Minerva Anestesiol. 2015. Deflandre E, Brichant JF, Bonhomme V. Obstructive sleep apnea and detection of non-adherence to CPAP in OSA: limits of the pre-anesthesia visit. Minerva Anestesiol. 2015.
97.
Zurück zum Zitat Jiang X, Yongxiang W, Wei Z, et al. Higher dose of warfarin for patients with pulmonary embolism complicated by obstructive sleep apnea hypopnea syndrome. Heart Lung J Crit Care. 2014;43:358–62.CrossRef Jiang X, Yongxiang W, Wei Z, et al. Higher dose of warfarin for patients with pulmonary embolism complicated by obstructive sleep apnea hypopnea syndrome. Heart Lung J Crit Care. 2014;43:358–62.CrossRef
98.
Zurück zum Zitat Thomsen T, Villebro N, Moller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev. 2014;3:CD002294.PubMed Thomsen T, Villebro N, Moller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev. 2014;3:CD002294.PubMed
99.
Zurück zum Zitat Khullar D, Maa J. The impact of smoking on surgical outcomes. J Am Coll Surg. 2012;215:418–26.CrossRefPubMed Khullar D, Maa J. The impact of smoking on surgical outcomes. J Am Coll Surg. 2012;215:418–26.CrossRefPubMed
100.
Zurück zum Zitat Deflandre E, Degey S, Clerdain AM, et al. Perioperative tobacco cessation: a crucial period to overcome clinical inertia and poor compliance. Rev Med Liege. 2010;65:332–7.PubMed Deflandre E, Degey S, Clerdain AM, et al. Perioperative tobacco cessation: a crucial period to overcome clinical inertia and poor compliance. Rev Med Liege. 2010;65:332–7.PubMed
101.
Zurück zum Zitat Wong J, Lam DP, Abrishami A, et al. Short-term preoperative smoking cessation and postoperative complications: a systematic review and meta-analysis. Can J Anaesth J Can Anesth. 2012;59:268–79.CrossRef Wong J, Lam DP, Abrishami A, et al. Short-term preoperative smoking cessation and postoperative complications: a systematic review and meta-analysis. Can J Anaesth J Can Anesth. 2012;59:268–79.CrossRef
102.
Zurück zum Zitat Colrain IM, Trinder J, Swan GE. The impact of smoking cessation on objective and subjective markers of sleep: review, synthesis, and recommendations. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2004;6:913–25.CrossRef Colrain IM, Trinder J, Swan GE. The impact of smoking cessation on objective and subjective markers of sleep: review, synthesis, and recommendations. Nicotine Tob Res Off J Soc Res Nicotine Tob. 2004;6:913–25.CrossRef
Metadaten
Titel
Obstructive Sleep Apnea and Smoking as a Risk Factor for Venous Thromboembolism Events: Review of the Literature on the Common Pathophysiological Mechanisms
verfasst von
Eric Deflandre
Stephanie Degey
Natacha Opsomer
Jean-Francois Brichant
Jean Joris
Publikationsdatum
01.03.2016
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 3/2016
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-015-2012-0

Weitere Artikel der Ausgabe 3/2016

Obesity Surgery 3/2016 Zur Ausgabe

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

23.04.2024 Ablationstherapie Nachrichten

Nach der Katheterablation von Vorhofflimmern kommt es bei etwa einem Drittel der Patienten zu Rezidiven, meist binnen eines Jahres. Wie sich spätere Rückfälle auf die Erfolgschancen einer erneuten Ablation auswirken, haben Schweizer Kardiologen erforscht.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

23.04.2024 Operationsvorbereitung Nachrichten

Derzeit wird empfohlen, eine Therapie mit GLP-1-Rezeptoragonisten präoperativ zu unterbrechen. Eine neue Studie nährt jedoch Zweifel an der Notwendigkeit der Maßnahme.

Ureterstriktur: Innovative OP-Technik bewährt sich

19.04.2024 EAU 2024 Kongressbericht

Die Ureterstriktur ist eine relativ seltene Komplikation, trotzdem bedarf sie einer differenzierten Versorgung. In komplexen Fällen wird dies durch die roboterassistierte OP-Technik gewährleistet. Erste Resultate ermutigen.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.