Oral Manifestation of Lymphomatoid Granulomatosis
- 14.03.2018
- Case Report
Erschienen in:
- Verfasst von
- Alessandro Antônio Costa Pereira
- Christian Barros Ferreira
- João Adolfo Costa Hanemann
- Livia Maris Ribeiro Paranaiba
- Patricia Peres Iucif Pereira
- Carla Isabelly Rodrigues-Fernandes
- Celeste Sánchez-Romero
- Oslei Paes de Almeida
- Felipe Paiva Fonseca
- Erschienen in
- Head and Neck Pathology | Ausgabe 2/2019
Abstract
Lymphomatoid granulomatosis (LYG) is a rare B-cell lymphoproliferative disorder driven by Esptein–Barr virus (EBV) that most commonly affects the lungs, although extra pulmonary sites like the central nervous system, skin, liver and kidney can also be involved. It is microscopically characterized by an angiocentric and angiodestructive growth pattern, predominantly composed by small T-cells, although a smaller population of atypical large B-cells is considered the true neoplastic component. Oral cavity involvement of LYG has rarely been described and the diagnosis of this neoplasm is very difficult. The aim of this report is to present a rare case of LYG affecting an 86-year-old female patient that was diagnosed due to an extensive, ulcerated and painful oral lesion affecting the hard palate. Detailed microscopic evaluation together with a large immunohistochemical study were necessary to achieve the correct diagnosis of LYG.
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- Titel
- Oral Manifestation of Lymphomatoid Granulomatosis
- Verfasst von
-
Alessandro Antônio Costa Pereira
Christian Barros Ferreira
João Adolfo Costa Hanemann
Livia Maris Ribeiro Paranaiba
Patricia Peres Iucif Pereira
Carla Isabelly Rodrigues-Fernandes
Celeste Sánchez-Romero
Oslei Paes de Almeida
Felipe Paiva Fonseca
- Publikationsdatum
- 14.03.2018
- Verlag
- Springer US
- Erschienen in
-
Head and Neck Pathology / Ausgabe 2/2019
Elektronische ISSN: 1936-0568 - DOI
- https://doi.org/10.1007/s12105-018-0910-x
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