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Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 1/2024

13.10.2023 | Original Article

Outcomes of Central Neck Dissection for Papillary Thyroid Carcinoma in Primary Versus Revision Setting

verfasst von: Hasan Alansari, Nalin Mathur, Husain Ahmadi, Zaki Hassan AlWatban, Naji Alamuddin, Omar Sabra

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Ausgabe 1/2024

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Abstract

Introduction

Surgery in the central compartment after previous thyroidectomy involves an increased risk of injury to critical organs, including the parathyroids and recurrent laryngeal nerve. Contrastingly, primary central neck dissection involves a relatively low operative risk.

Objective

This study aimed to compare the outcomes of central neck dissection in primary versus revision settings with respect to the lymph node yield and complication rates.

Methods

This single-center prospective study included patients who underwent primary or revision neck dissection surgery for histologically confirmed thyroid malignancy between January 2018 and January 2022.

Results

We included 30 patients who underwent total thyroidectomy with primary central neck dissection and 29 patients who underwent central neck dissection following remote thyroidectomy with or without previous central dissection. There was no significant between-group difference in postoperative complications, including permanent hypocalcemia and recurrent laryngeal nerve injury. However, both groups showed a significant postoperative decrease in calcium levels even though calcium and parathyroid hormone levels were within reference range.

Conclusion

Although many surgeons fear revision central neck dissection, it appears to have similar therapeutic outcomes and complication rates as primary neck dissection for papillary thyroid cancer. Specifically, there were no between-group differences in the lymph node yield, hypoparathyroidism, or recurrent laryngeal nerve paralysis. Patients with normocalcemia showed a significant postoperative reduction in calcium levels, suggesting subclinical parathyroid insufficiency.
Literatur
1.
Zurück zum Zitat Carty SE, Cooper DS, Doherty GM, Duh Q-Y, Kloos RT, Mandel SJ et al (2009) Consensus Statement on the Terminology and Classification of Central Neck Dissection for Thyroid Cancer [Internet]. Available from: www.liebertpub.com Carty SE, Cooper DS, Doherty GM, Duh Q-Y, Kloos RT, Mandel SJ et al (2009) Consensus Statement on the Terminology and Classification of Central Neck Dissection for Thyroid Cancer [Internet]. Available from: www.​liebertpub.​com
2.
Zurück zum Zitat Hall CM, LaSeur DC, Snyder SK, Lairmore TC (2018) Reoperative central lymph node dissection for incidental papillary thyroid cancer can be performed safely: a retrospective review. Int J Surg 56:102–107CrossRefPubMed Hall CM, LaSeur DC, Snyder SK, Lairmore TC (2018) Reoperative central lymph node dissection for incidental papillary thyroid cancer can be performed safely: a retrospective review. Int J Surg 56:102–107CrossRefPubMed
3.
Zurück zum Zitat Lim H, Devesa SS, Sosa JA, Check D, Kitahara CM, JAMA - Journal of the American Medical Association (2017) Trends in thyroid cancer incidence and mortality in the United States, 1974–2013 [Internet]. Vol. 317,. American Medical Association; [cited 2021 Apr 19]. p. 1338–48. Available from: https://pubmed.ncbi.nlm.nih.gov/28362912/ Lim H, Devesa SS, Sosa JA, Check D, Kitahara CM, JAMA - Journal of the American Medical Association (2017) Trends in thyroid cancer incidence and mortality in the United States, 1974–2013 [Internet]. Vol. 317,. American Medical Association; [cited 2021 Apr 19]. p. 1338–48. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​28362912/​
4.
Zurück zum Zitat Aljabri KS, Bokhari SA, al Shareef MA, Khan PM An 18-year study of thyroid carcinoma in the western region of Saudi Arabia: A retrospective single-center study in a community hospital. Annals of Saudi Medicine [Internet]. 2018 Sep 1 [cited 2021 Apr 19];38(5):336–43. Available from: https://pubmed.ncbi.nlm.nih.gov/30284988/ Aljabri KS, Bokhari SA, al Shareef MA, Khan PM An 18-year study of thyroid carcinoma in the western region of Saudi Arabia: A retrospective single-center study in a community hospital. Annals of Saudi Medicine [Internet]. 2018 Sep 1 [cited 2021 Apr 19];38(5):336–43. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​30284988/​
5.
Zurück zum Zitat Hughes DT, Doherty GM (2011) Central neck dissection for papillary thyroid cancer. Cancer Control 18(2):83–88CrossRefPubMed Hughes DT, Doherty GM (2011) Central neck dissection for papillary thyroid cancer. Cancer Control 18(2):83–88CrossRefPubMed
6.
Zurück zum Zitat Kim MK, Mandel SH, Baloch Z, Livolsi VA, Langer JE, Didonato L et al (2004) Morbidity Following Central Compartment Reoperation for Recurrent or Persistent Thyroid Cancer [Internet]. Vol. 130, Arch Otolaryngol Head Neck Surg. Available from: http://archotol.jamanetwork.com/ Kim MK, Mandel SH, Baloch Z, Livolsi VA, Langer JE, Didonato L et al (2004) Morbidity Following Central Compartment Reoperation for Recurrent or Persistent Thyroid Cancer [Internet]. Vol. 130, Arch Otolaryngol Head Neck Surg. Available from: http://​archotol.​jamanetwork.​com/​
7.
Zurück zum Zitat Urken ML, Milas M, Randolph GW, Tufano R, Bergman D, Bernet V et al (2015) Management of recurrent and persistent metastatic lymph nodes in well-differentiated thyroid cancer: a multifactorial decision-making guide for the thyroid cancer care collaborative. Head and Neck, vol 37. John Wiley and Sons Inc., pp 605–614 Urken ML, Milas M, Randolph GW, Tufano R, Bergman D, Bernet V et al (2015) Management of recurrent and persistent metastatic lymph nodes in well-differentiated thyroid cancer: a multifactorial decision-making guide for the thyroid cancer care collaborative. Head and Neck, vol 37. John Wiley and Sons Inc., pp 605–614
8.
Zurück zum Zitat Chisholm EJ, Kulinskaya E, Tolley NS (2009) Systematic review and meta-analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy alone. Laryngoscope 119(6):1135–1139CrossRefPubMed Chisholm EJ, Kulinskaya E, Tolley NS (2009) Systematic review and meta-analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy alone. Laryngoscope 119(6):1135–1139CrossRefPubMed
9.
Zurück zum Zitat Lamartina L, Borget I, Mirghani H, al Ghuzlan A, Berdelou A, Bidault F et al (2017) Surgery for neck recurrence of differentiated thyroid cancer: outcomes and risk factors. J Clin Endocrinol Metab 102(3):1020–1031PubMed Lamartina L, Borget I, Mirghani H, al Ghuzlan A, Berdelou A, Bidault F et al (2017) Surgery for neck recurrence of differentiated thyroid cancer: outcomes and risk factors. J Clin Endocrinol Metab 102(3):1020–1031PubMed
10.
Zurück zum Zitat Orloff LA, Wiseman SM, Bernet VJ, Fahey TJ 3rd, Shaha AR, Shindo ML, Snyder SK, Stack BC Jr, Sunwoo JB, Wang MB (2018) Thyroid 28(7):830–841 American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in AdultsCrossRefPubMed Orloff LA, Wiseman SM, Bernet VJ, Fahey TJ 3rd, Shaha AR, Shindo ML, Snyder SK, Stack BC Jr, Sunwoo JB, Wang MB (2018) Thyroid 28(7):830–841 American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, Prevention, and Management in AdultsCrossRefPubMed
11.
Zurück zum Zitat Haugen B, Alexander E, Bible K, Doherty G, Mandel S, Nikiforov Y, Pacini F, Randolph G, Sawka A, Schlumberger M, Schuff K, Sherman S, Sosa J, Steward D, Tuttle R, Wartofsky L (2016) 2015 american thyroid Association Management Guidelines for adult patients with thyroid nodules and differentiated thyroid Cancer: the american thyroid Association Guidelines Task Force on thyroid nodules and differentiated thyroid Cancer. Thyroid 26(1):1–133CrossRefPubMedPubMedCentral Haugen B, Alexander E, Bible K, Doherty G, Mandel S, Nikiforov Y, Pacini F, Randolph G, Sawka A, Schlumberger M, Schuff K, Sherman S, Sosa J, Steward D, Tuttle R, Wartofsky L (2016) 2015 american thyroid Association Management Guidelines for adult patients with thyroid nodules and differentiated thyroid Cancer: the american thyroid Association Guidelines Task Force on thyroid nodules and differentiated thyroid Cancer. Thyroid 26(1):1–133CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Lindblom P, Valdemarsson S, Lindergård B, Westerdahl J, Bergenfelz A (2001) Decreased levels of Ionized Calcium One Year after Hemithyroidectomy: importance of reduced thyroid hormones. Hormone Res Paediatrics 55(2):81–87CrossRef Lindblom P, Valdemarsson S, Lindergård B, Westerdahl J, Bergenfelz A (2001) Decreased levels of Ionized Calcium One Year after Hemithyroidectomy: importance of reduced thyroid hormones. Hormone Res Paediatrics 55(2):81–87CrossRef
16.
Zurück zum Zitat Bergenfelz A, Ahr, eacuten B (1993) Calcium metabolism after Hemithyroidectomy. Horm Res 39(1–2):56–60CrossRefPubMed Bergenfelz A, Ahr, eacuten B (1993) Calcium metabolism after Hemithyroidectomy. Horm Res 39(1–2):56–60CrossRefPubMed
Metadaten
Titel
Outcomes of Central Neck Dissection for Papillary Thyroid Carcinoma in Primary Versus Revision Setting
verfasst von
Hasan Alansari
Nalin Mathur
Husain Ahmadi
Zaki Hassan AlWatban
Naji Alamuddin
Omar Sabra
Publikationsdatum
13.10.2023
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe 1/2024
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-023-04261-8

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