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Urolithiasis

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23.03.2021 | Original Paper

Patients’ poor performance status is an independent risk factor for urosepsis induced by kidney and ureteral stones

verfasst von: Mika Kino, Takumi Hayashi, Daichi Hino, Takako Nakada, Hiroki Kitoh, Koichiro Akakura

Erschienen in: Urolithiasis | Ausgabe 5/2021

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Abstract

This study was aimed to identify the risk factors for urosepsis caused by kidney and ureteral stones. One hundred and nine patients who had kidney or ureteral stones and who were treated with trans-ureteral lithotripsy (TUL) at our institution from 2016 to 2020 were included. We investigated the risk factors for urosepsis caused by kidney or ureteral stones that occurred prior to TUL. Thirty patients (28%) had urosepsis prior to TUL. Patients were divided into a urosepsis group (n = 30, 28%) and a non-urosepsis group (n = 79, 72%). Patients’ characteristics (gender, age, performance status [PS] score, presence of diabetes mellitus, and skeletal muscle mass), as well as their stone and urine characteristics (stone size, presence of obstructive ureteral stones, stone composition, and urine and stone cultures), were compared between the two groups. When compared to the non-urosepsis group, patients with urosepsis were more likely to be older (p < 0.001), female (p < 0.001), with lower skeletal muscle mass (p < 0.001) and with poor PSs (p < 0.001). For stone and urine characteristics, infection stones (p = 0.01), positive urine (p < 0.001) and stone culture (p = 0.007) were more often detected in patients with urosepsis. A multivariate analysis showed patients’ poor PS to be an independent risk factor for urosepsis due to kidney and ureteral stones (OR = 15.7; 95% CI = 2.2–115, p = 0.007). Our study revealed that the most significant risk factor for urosepsis caused by kidney and ureteral stones was the patients’ poor PS.

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Titel: Patients’ poor performance status is an independent risk factor for urosepsis induced by kidney and ureteral stones
verfasst von: Mika Kino
Takumi Hayashi
Daichi Hino
Takako Nakada
Hiroki Kitoh
Koichiro Akakura
Publikationsdatum: 23.03.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Urolithiasis / Ausgabe 5/2021
Print ISSN: 2194-7228
Elektronische ISSN: 2194-7236
DOI: https://doi.org/10.1007/s00240-021-01256-4

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